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G5ECN9

- G5ECN9_CAEEL

UniProt

G5ECN9 - G5ECN9_CAEEL

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Protein
Submitted name: Prohormone convertase 2
Gene
egl-3, pc2, C51E3.7, CELE_C51E3.7
Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. serine-type endopeptidase activity Source: RefGenome

GO - Biological processi

  1. negative regulation of turning behavior involved in mating Source: WormBase
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotations

Protein family/group databases

MEROPSiS08.109.

Names & Taxonomyi

Protein namesi
Submitted name:
Prohormone convertase 2Imported
Submitted name:
Protein EGL-3, isoform aImported
Gene namesi
Name:egl-3Imported
Synonyms:pc2Imported
ORF Names:C51E3.7Imported, CELE_C51E3.7Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome V

Organism-specific databases

WormBaseiC51E3.7a; CE08940; WBGene00001172; egl-3.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: WormBase
  2. extracellular space Source: RefGenome
Complete GO annotation...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00750000117358.
KOiK01360.
OMAiHKIQSGN.
OrthoDBiEOG7BW0JD.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5ECN9-1 [UniParc]FASTAAdd to Basket

« Hide

MKNTHVDLIC VFLSIFIGIG EAVDVYTNHF HVHLKEGGGL EDAHRIAKRH    50
GFINRGQVAA SDNEYHFVQP ALVHARTRRS AGHHAKLHND DEVLHVEQLK 100
GYTRTKRGYR PLEQRLESQF DFSAVMSPSD PLYGYQWYLK NTGQAGGKAR 150
LDLNVERAWA MGFTGKNITT AIMDDGVDYM HPDIKNNFNA EASYDFSSND 200
PFPYPRYTDD WFNSHGTRCA GEIVAARDNG VCGVGVAYDG KVAGIRMLDQ 250
PYMTDLIEAN SMGHEPSKIH IYSASWGPTD DGKTVDGPRN ATMRAIVRGV 300
NEGRNGLGSI FVWASGDGGE DDDCNCDGYA ASMWTISINS AINNGENAHY 350
DESCSSTLAS TFSNGGRNPE TGVATTDLYG RCTRSHSGTS AAAPEAAGVF 400
ALALEANPSL TWRDLQHLTV LTSSRNSLFD GRCRDFPSLG INDNHRDSHG 450
NCSHFEWQMN GVGLEYNHLF GFGVLDAAEM VMLAMAWKTS PPRYHCTAGL 500
IDTPHEIPAD GNLILEINTD GCAGSQFEVR YLEHVQAVVS FNSTRRGDTT 550
LYLISPMGTR TMILSRRPKD DDSKDGFTNW PFMTTHTWGE NPTGKWRLVA 600
RFQGPGAHAG TLKKFELMLH GTREAPYNLI EPIVGQTNKK LDTVQKAHKR 650
SH 652
Length:652
Mass (Da):72,046
Last modified:December 14, 2011 - v1
Checksum:i39E378E75C081A2B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U04995 mRNA. Translation: AAA56868.1.
Z78410 Genomic DNA. Translation: CAB01635.1.
PIRiT20131.
RefSeqiNP_001023732.1. NM_001028561.3.
UniGeneiCel.18027.

Genome annotation databases

EnsemblMetazoaiC51E3.7a; C51E3.7a; WBGene00001172.
GeneIDi179412.
KEGGicel:CELE_C51E3.7.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U04995 mRNA. Translation: AAA56868.1 .
Z78410 Genomic DNA. Translation: CAB01635.1 .
PIRi T20131.
RefSeqi NP_001023732.1. NM_001028561.3.
UniGenei Cel.18027.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi S08.109.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai C51E3.7a ; C51E3.7a ; WBGene00001172 .
GeneIDi 179412.
KEGGi cel:CELE_C51E3.7.

Organism-specific databases

CTDi 179412.
WormBasei C51E3.7a ; CE08940 ; WBGene00001172 ; egl-3.

Phylogenomic databases

GeneTreei ENSGT00750000117358.
KOi K01360.
OMAi HKIQSGN.
OrthoDBi EOG7BW0JD.

Miscellaneous databases

NextBioi 905280.
PROi G5ECN9.

Family and domain databases

Gene3Di 2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProi IPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view ]
PANTHERi PTHR10795. PTHR10795. 1 hit.
Pfami PF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view ]
PRINTSi PR00723. SUBTILISIN.
SUPFAMi SSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Isolation of CELPC2, a cDNA that encodes a putative Kex2-like prohormone convertase in C. elegans."
    Gomez-Saladin E., Wilson D.L., Dickerson I.M.
    Worm Breed. Gaz. 13:51-51(1993)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BA713Imported.
    Tissue: Whole organismImported.
  2. "Isolation and in situ localization of a cDNA encoding a Kex2-like prohormone convertase in the nematode Caenorhabditis elegans."
    Gomez-Saladin E., Wilson D.L., Dickerson I.M.
    Cell. Mol. Neurobiol. 14:9-25(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BA713Imported.
    Tissue: Whole organismImported.
  3. WormBase Consortium
    Wilkinson J.
    Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.
  4. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  5. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Science 282:2012-2018(1998)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiG5ECN9_CAEEL
AccessioniPrimary (citable) accession number: G5ECN9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: September 3, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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