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G5EC23

- G5EC23_CAEEL

UniProt

G5EC23 - G5EC23_CAEEL

Protein
Submitted name:

Host cell factor 1

Gene

hcf-1

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: IntAct
    2. transcription factor binding Source: WormBase

    GO - Biological processi

    1. dauer exit Source: WormBase
    2. determination of adult lifespan Source: WormBase
    3. negative regulation of transcription by transcription factor localization Source: WormBase
    4. response to cadmium ion Source: WormBase
    5. response to oxidative stress Source: WormBase

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Host cell factor 1Imported
    Submitted name:
    Protein HCF-1Imported
    Gene namesi
    Name:hcf-1Imported
    ORF Names:C46A5.9Imported, CELE_C46A5.9Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome IV

    Organism-specific databases

    WormBaseiC46A5.9; CE26914; WBGene00001827; hcf-1.

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: WormBase

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00720000108539.
    KOiK14966.
    OMAiHTSANIG.
    OrthoDBiEOG790G05.

    Family and domain databases

    Gene3Di2.120.10.80. 1 hit.
    2.130.10.80. 1 hit.
    2.60.40.10. 2 hits.
    InterProiIPR003961. Fibronectin_type3.
    IPR015916. Gal_Oxidase_b-propeller.
    IPR013783. Ig-like_fold.
    IPR015915. Kelch-typ_b-propeller.
    [Graphical view]
    SMARTiSM00060. FN3. 2 hits.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 2 hits.
    PROSITEiPS50853. FN3. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G5EC23-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDEDVGLEAT NYSRGDESRS EEQEKNVVRW RIVQQSTGPN PKPRHGHRAV    50
    VLKELIVIFG GGNEGMIDEL HAYNTQKREW TAPQCCGDVP TPAAAFGAIS 100
    LGNKIYRFGG MTEYGKYTND LYELQSTRWE WRRLNPRVHS NGHLPCPRIG 150
    HSFVVSQKSQ KAYVFGGLSN DLNDPKRNVP HYLDDLYVIN LSGPQHLIWE 200
    KLNATGPGPI SRESHTAVIY EKDSISRMVV YGGMNGVRLG DLWYLNLNTL 250
    HWTEIKFDDP RTGIPPMPRS LHSSVLIGDK MFVYGGWVPL LEHASTEQQT 300
    EKEWKCTSSL GCWNITEDRW VPLHLYCSDE DTIPRGRAGH CAAAVGDRMY 350
    IWSGRDGYRK AWSNQVCCRD MWLLDTILPE QPGKVQLGRA GFNSLEISWP 400
    IVQGASGYFL QIGFGDAKEQ SVSPIKRATT SPRKQPSIVP PSQKETEQSP 450
    KKPQGTAPSI ISTQGTTYTA PADPKPATDE GGLPQDLFED TEKNETASPK 500
    RSNDAQSADS STCEQKKTDE SGLEEDSEKD QKPSDAGETD EMKEENGDDD 550
    LPWFDVGIID KATINVTHYF NDRQQSLEKQ LNDLIDHNAF KCVNDSVFTT 600
    EDKIPLINGQ SYRFRVSAIN GLGKGAWSET ASCKTCVPGY PSAPSSIRIT 650
    KSHEGAQLTW EPPSNTNISG KIIEYSVYLA VKNQSANSAD SQLAFMRVYC 700
    GPQADCQVLQ SNLGTAFVDQ TNKPAIIFRI AARNEKGYGP ATQVRWLQDQ 750
    QKIPVRTNYP NNSGFIYQQH GGQQKRARFD HQ 782
    Length:782
    Mass (Da):87,359
    Last modified:December 14, 2011 - v1
    Checksum:i1DF7775CA82B8309
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF072907 mRNA. Translation: AAD12580.1.
    FO080769 Genomic DNA. Translation: CCD66593.1.
    PIRiT29816.
    T43277.
    RefSeqiNP_501279.1. NM_068878.4.
    UniGeneiCel.17455.

    Genome annotation databases

    EnsemblMetazoaiC46A5.9; C46A5.9; WBGene00001827.
    GeneIDi177560.
    KEGGicel:CELE_C46A5.9.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF072907 mRNA. Translation: AAD12580.1 .
    FO080769 Genomic DNA. Translation: CCD66593.1 .
    PIRi T29816.
    T43277.
    RefSeqi NP_501279.1. NM_068878.4.
    UniGenei Cel.17455.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai C46A5.9 ; C46A5.9 ; WBGene00001827 .
    GeneIDi 177560.
    KEGGi cel:CELE_C46A5.9.

    Organism-specific databases

    CTDi 177560.
    WormBasei C46A5.9 ; CE26914 ; WBGene00001827 ; hcf-1.

    Phylogenomic databases

    GeneTreei ENSGT00720000108539.
    KOi K14966.
    OMAi HTSANIG.
    OrthoDBi EOG790G05.

    Miscellaneous databases

    NextBioi 897368.
    PROi G5EC23.

    Family and domain databases

    Gene3Di 2.120.10.80. 1 hit.
    2.130.10.80. 1 hit.
    2.60.40.10. 2 hits.
    InterProi IPR003961. Fibronectin_type3.
    IPR015916. Gal_Oxidase_b-propeller.
    IPR013783. Ig-like_fold.
    IPR015915. Kelch-typ_b-propeller.
    [Graphical view ]
    SMARTi SM00060. FN3. 2 hits.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 2 hits.
    PROSITEi PS50853. FN3. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. WormBase Consortium
      Johnson D., Stellyes L.
      Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Bristol N2Imported.
    2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      Caenorhabditis elegans Sequencing Consortium
      Science 282:2012-2018(1998)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: Bristol N2Imported.
    3. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.
    4. "Selected elements of herpes simplex virus accessory factor HCF are highly conserved in Caenorhabditis elegans."
      Liu Y., Hengartner M.O., Herr W.
      Mol. Cell. Biol. 19:909-915(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiG5EC23_CAEEL
    AccessioniPrimary (citable) accession number: G5EC23
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3