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G5EC23

- G5EC23_CAEEL

UniProt

G5EC23 - G5EC23_CAEEL

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Protein
Submitted name: Host cell factor 1
Gene
hcf-1, C46A5.9, CELE_C46A5.9
Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: IntAct
  2. transcription factor binding Source: WormBase

GO - Biological processi

  1. dauer exit Source: WormBase
  2. determination of adult lifespan Source: WormBase
  3. negative regulation of transcription by transcription factor localization Source: WormBase
  4. response to cadmium ion Source: WormBase
  5. response to oxidative stress Source: WormBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Host cell factor 1Imported
Submitted name:
Protein HCF-1Imported
Gene namesi
Name:hcf-1Imported
ORF Names:C46A5.9Imported, CELE_C46A5.9Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome IV

Organism-specific databases

WormBaseiC46A5.9; CE26914; WBGene00001827; hcf-1.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: WormBase
Complete GO annotation...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00720000108539.
KOiK14966.
OMAiHTSANIG.
OrthoDBiEOG790G05.

Family and domain databases

Gene3Di2.120.10.80. 1 hit.
2.130.10.80. 1 hit.
2.60.40.10. 2 hits.
InterProiIPR003961. Fibronectin_type3.
IPR015916. Gal_Oxidase_b-propeller.
IPR013783. Ig-like_fold.
IPR015915. Kelch-typ_b-propeller.
[Graphical view]
SMARTiSM00060. FN3. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 2 hits.
PROSITEiPS50853. FN3. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5EC23-1 [UniParc]FASTAAdd to Basket

« Hide

MDEDVGLEAT NYSRGDESRS EEQEKNVVRW RIVQQSTGPN PKPRHGHRAV    50
VLKELIVIFG GGNEGMIDEL HAYNTQKREW TAPQCCGDVP TPAAAFGAIS 100
LGNKIYRFGG MTEYGKYTND LYELQSTRWE WRRLNPRVHS NGHLPCPRIG 150
HSFVVSQKSQ KAYVFGGLSN DLNDPKRNVP HYLDDLYVIN LSGPQHLIWE 200
KLNATGPGPI SRESHTAVIY EKDSISRMVV YGGMNGVRLG DLWYLNLNTL 250
HWTEIKFDDP RTGIPPMPRS LHSSVLIGDK MFVYGGWVPL LEHASTEQQT 300
EKEWKCTSSL GCWNITEDRW VPLHLYCSDE DTIPRGRAGH CAAAVGDRMY 350
IWSGRDGYRK AWSNQVCCRD MWLLDTILPE QPGKVQLGRA GFNSLEISWP 400
IVQGASGYFL QIGFGDAKEQ SVSPIKRATT SPRKQPSIVP PSQKETEQSP 450
KKPQGTAPSI ISTQGTTYTA PADPKPATDE GGLPQDLFED TEKNETASPK 500
RSNDAQSADS STCEQKKTDE SGLEEDSEKD QKPSDAGETD EMKEENGDDD 550
LPWFDVGIID KATINVTHYF NDRQQSLEKQ LNDLIDHNAF KCVNDSVFTT 600
EDKIPLINGQ SYRFRVSAIN GLGKGAWSET ASCKTCVPGY PSAPSSIRIT 650
KSHEGAQLTW EPPSNTNISG KIIEYSVYLA VKNQSANSAD SQLAFMRVYC 700
GPQADCQVLQ SNLGTAFVDQ TNKPAIIFRI AARNEKGYGP ATQVRWLQDQ 750
QKIPVRTNYP NNSGFIYQQH GGQQKRARFD HQ 782
Length:782
Mass (Da):87,359
Last modified:December 14, 2011 - v1
Checksum:i1DF7775CA82B8309
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF072907 mRNA. Translation: AAD12580.1.
FO080769 Genomic DNA. Translation: CCD66593.1.
PIRiT29816.
T43277.
RefSeqiNP_501279.1. NM_068878.4.
UniGeneiCel.17455.

Genome annotation databases

EnsemblMetazoaiC46A5.9; C46A5.9; WBGene00001827.
GeneIDi177560.
KEGGicel:CELE_C46A5.9.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF072907 mRNA. Translation: AAD12580.1 .
FO080769 Genomic DNA. Translation: CCD66593.1 .
PIRi T29816.
T43277.
RefSeqi NP_501279.1. NM_068878.4.
UniGenei Cel.17455.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai C46A5.9 ; C46A5.9 ; WBGene00001827 .
GeneIDi 177560.
KEGGi cel:CELE_C46A5.9.

Organism-specific databases

CTDi 177560.
WormBasei C46A5.9 ; CE26914 ; WBGene00001827 ; hcf-1.

Phylogenomic databases

GeneTreei ENSGT00720000108539.
KOi K14966.
OMAi HTSANIG.
OrthoDBi EOG790G05.

Miscellaneous databases

NextBioi 897368.
PROi G5EC23.

Family and domain databases

Gene3Di 2.120.10.80. 1 hit.
2.130.10.80. 1 hit.
2.60.40.10. 2 hits.
InterProi IPR003961. Fibronectin_type3.
IPR015916. Gal_Oxidase_b-propeller.
IPR013783. Ig-like_fold.
IPR015915. Kelch-typ_b-propeller.
[Graphical view ]
SMARTi SM00060. FN3. 2 hits.
[Graphical view ]
SUPFAMi SSF49265. SSF49265. 2 hits.
PROSITEi PS50853. FN3. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. WormBase Consortium
    Johnson D., Stellyes L.
    Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.
  2. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Science 282:2012-2018(1998)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Bristol N2Imported.
  3. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.
  4. "Selected elements of herpes simplex virus accessory factor HCF are highly conserved in Caenorhabditis elegans."
    Liu Y., Hengartner M.O., Herr W.
    Mol. Cell. Biol. 19:909-915(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiG5EC23_CAEEL
AccessioniPrimary (citable) accession number: G5EC23
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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