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Protein
Submitted name:

ERM-1B

Gene

erm-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • actin binding Source: InterPro
  • structural molecule activity Source: WormBase

GO - Biological processi

  • actin filament organization Source: WormBase
  • morphogenesis of an epithelium Source: WormBase
  • nematode larval development Source: WormBase
  • protein localization to basolateral plasma membrane Source: WormBase
  • tube formation Source: WormBase

Enzyme and pathway databases

ReactomeiR-CEL-373752 Netrin-1 signaling
R-CEL-437239 Recycling pathway of L1

Names & Taxonomyi

Protein namesi
Submitted name:
ERM-1BImported
Submitted name:
Ezrin/Radixin/MoesinImported
Gene namesi
Name:erm-1Imported
ORF Names:C01G8.5Imported, CELE_C01G8.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome I

Organism-specific databases

WormBaseiC01G8.5b ; CE07806 ; WBGene00001333 ; erm-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiWBGene00001333

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
nrfl-1G5EC642EBI-313664,EBI-313674

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6239.C01G8.5b

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 297FERMInterPro annotationAdd BLAST291

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili308 – 404Sequence analysisAdd BLAST97
Coiled coili502 – 522Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3529 Eukaryota
ENOG410XQFP LUCA
GeneTreeiENSGT00920000148976
OMAiDEQDENH
OrthoDBiEOG091G06UO

Family and domain databases

CDDicd14473 FERM_B-lobe, 1 hit
Gene3Di1.20.80.10, 1 hit
1.25.40.1020, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR019749 Band_41_domain
IPR011174 ERM
IPR011259 ERM_C_dom
IPR000798 Ez/rad/moesin-like
IPR014352 FERM/acyl-CoA-bd_prot_sf
IPR035963 FERM_2
IPR019748 FERM_central
IPR019747 FERM_CS
IPR000299 FERM_domain
IPR018979 FERM_N
IPR018980 FERM_PH-like_C
IPR008954 Moesin_tail_sf
IPR011993 PH-like_dom_sf
IPR029071 Ubiquitin-like_domsf
PfamiView protein in Pfam
PF00769 ERM, 1 hit
PF09380 FERM_C, 1 hit
PF00373 FERM_M, 1 hit
PF09379 FERM_N, 1 hit
PIRSFiPIRSF002305 ERM, 1 hit
PRINTSiPR00935 BAND41
PR00661 ERMFAMILY
SMARTiView protein in SMART
SM00295 B41, 1 hit
SM01196 FERM_C, 1 hit
SUPFAMiSSF47031 SSF47031, 1 hit
SSF48678 SSF48678, 1 hit
SSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS00660 FERM_1, 1 hit
PS00661 FERM_2, 1 hit
PS50057 FERM_3, 1 hit

Sequencei

Sequence statusi: Complete.

G5EBK3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAAGDINVR VTSMDSELEF AIQSSTTGKQ LFDQVVKTIG LREIWYFGLQ
60 70 80 90 100
YTDNKGFPTW LKLNKKVLSQ DVKKDPTLVF KFRAKFYPED VAEEIIQDVT
110 120 130 140 150
MRLFYLQVKD GILSDEIYCP PETSVLLASY AMQAKYGDYV PETHVAGCLT
160 170 180 190 200
ADRLLPQRVL GQFKLNSEEW ERRIMTWWAD HRATTREQAM LEYLKIAQDL
210 220 230 240 250
EMYGVNYFEI RNKKGTDLYL GVDALGLNIY DKADRLSPKV GFPWSEIRNI
260 270 280 290 300
SFNDKKFVIK PIDKKAHDFV FYAPRLRINK RILALCMGNH ELYMRRRKPD
310 320 330 340 350
TIEVQQMKQQ AREDRALKIA EQEKLTREMS AREEAEQRQR DAEKRMAQMQ
360 370 380 390 400
EDMERARLEL AEAHNTIHSL EAQLKQLQLA KQALEQKEYE LRELTAQLQS
410 420 430 440 450
EKAMSDGERR HLRDQVDARE REVFSMREEV ERQTTVTRQL QTQIHSQQHT
460 470 480 490 500
QHYSNSHHVS NGHAHDETAT DDEDNGATEL TNDADQNVPQ HELERVTAAE
510 520 530 540 550
KNIQIKNKLD MLTRELDSVK DQNAVTDYDV LHMENKKAGR DKYKTLRQIR
560
GGNTKRRIDQ YENM
Length:564
Mass (Da):66,000
Last modified:December 14, 2011 - v1
Checksum:i06E157B354BD3FA0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB107269 mRNA Translation: BAC98355.1
AB107270 Genomic DNA Translation: BAC98358.1
BX284601 Genomic DNA Translation: CCD62463.1
PIRiT29263
RefSeqiNP_491560.1, NM_059159.3
UniGeneiCel.5070

Genome annotation databases

EnsemblMetazoaiC01G8.5b; C01G8.5b; WBGene00001333
GeneIDi172174

Similar proteinsi

Entry informationi

Entry nameiG5EBK3_CAEEL
AccessioniPrimary (citable) accession number: G5EBK3
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: June 20, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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