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Protein
Submitted name:

CUG triplet repeat, RNA binding protein 1, isoform CRA_c

Gene

CELF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CUG triplet repeat, RNA binding protein 1, isoform CRA_cImported
Submitted name:
CUGBP Elav-like family member 1Imported
Gene namesi
Name:CELF1Imported
Synonyms:CUGBP1Imported
ORF Names:hCG_25183Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149187.17
HGNCiHGNC:2549 CELF1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149187

PTM / Processingi

Proteomic databases

MaxQBiG5EA30
PeptideAtlasiG5EA30
PRIDEiG5EA30

Expressioni

Gene expression databases

BgeeiENSG00000149187
ExpressionAtlasiG5EA30 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 126RRMInterPro annotationAdd BLAST84
Domaini135 – 215RRMInterPro annotationAdd BLAST81
Domaini429 – 507RRMInterPro annotationAdd BLAST79

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili218 – 238Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0146 Eukaryota
ENOG410XNTW LUCA
GeneTreeiENSGT00560000076837
OMAiSKCFGHT
OrthoDBiEOG091G19O1

Family and domain databases

CDDicd12631 RRM1_CELF1_2_Bruno, 1 hit
cd12634 RRM2_CELF1_2, 1 hit
cd12638 RRM3_CELF1_2, 1 hit
Gene3Di3.30.70.330, 3 hits
InterProiView protein in InterPro
IPR034196 CELF1/2_RRM1
IPR034198 CELF1/2_RRM2
IPR034199 CELF1/2_RRM3
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 3 hits
SMARTiView protein in SMART
SM00360 RRM, 3 hits
SUPFAMiSSF54928 SSF54928, 3 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 3 hits

Sequencei

Sequence statusi: Complete.

G5EA30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAFKLDFLP EMMVDHCSLN SSPVSKKMNG TLDHPDQPDL DAIKMFVGQV
60 70 80 90 100
PRTWSEKDLR ELFEQYGAVY EINVLRDRSQ NPPQSKGCCF VTFYTRKAAL
110 120 130 140 150
EAQNALHNMK VLPGMHHPIQ MKPADSEKNN AVEDRKLFIG MISKKCTEND
160 170 180 190 200
IRVMFSSFGQ IEECRILRGP DGLSRGCAFV TFTTRAMAQT AIKAMHQAQT
210 220 230 240 250
MEGCSSPMVV KFADTQKDKE QKRMAQQLQQ QMQQISAASV WGNLAGLNTL
260 270 280 290 300
GPQYLALYLQ LLQQTASSGN LNTLSSLHPM GGLNAMQLQN LAALAAAASA
310 320 330 340 350
AQNTPSGTNA LTTSSSPLSV LTSSAGSSPS SSSSNSVNPI ASLGALQTLA
360 370 380 390 400
GATAGLNVGS LAGMAALNGG LGSSGLSNGT GSTMEALTQA YSGIQQYAAA
410 420 430 440 450
ALPTLYNQNL LTQQSIGAAG SQKEGPEGAN LFIYHLPQEF GDQDLLQMFM
460 470 480 490 500
PFGNVVSAKV FIDKQTNLSK CFGFVSYDNP VSAQAAIQSM NGFQIGMKRL
510
KVQLKRSKND SKPY
Length:514
Mass (Da):55,143
Last modified:December 14, 2011 - v1
Checksum:i31E7DF974827F9B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC090559 Genomic DNA No translation available.
CH471064 Genomic DNA Translation: EAW67908.1
RefSeqiNP_001317201.1, NM_001330272.1
XP_011518154.1, XM_011519852.2
XP_016872590.1, XM_017017101.1
XP_016872592.1, XM_017017103.1
XP_016872593.1, XM_017017104.1
UniGeneiHs.595333

Genome annotation databases

EnsembliENST00000531165; ENSP00000436864; ENSG00000149187
GeneIDi10658
UCSCiuc001nfp.4 human

Similar proteinsi

Entry informationi

Entry nameiG5EA30_HUMAN
AccessioniPrimary (citable) accession number: G5EA30
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health