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Protein
Submitted name:

NF-kappa-B inhibitor beta

Gene

NFKBIB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
NF-kappa-B inhibitor betaImported
Gene namesi
Name:NFKBIBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:7798. NFKBIB.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000104825.

PTM / Processingi

Proteomic databases

PaxDbiG5E9C2.
PeptideAtlasiG5E9C2.
PRIDEiG5E9C2.

Expressioni

Gene expression databases

BgeeiENSG00000104825.
ExpressionAtlasiG5E9C2. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000312988.

Structurei

3D structure databases

ProteinModelPortaliG5E9C2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 212ANK_REP_REGIONInterPro annotationAdd BLAST212

Sequence similaritiesi

Contains 3 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00550000074527.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 5 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5E9C2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLQNDLGQT ALHLAAILGE TSTVEKLYAA GAGLCVAERR GHTALHLACR
60 70 80 90 100
VGAHACARAL LQPRPRRPRE APDTYLAQGP DRTPDTNHTP VALYPDSDLE
110 120 130 140 150
KEEEESEEDW KLQLEAENYE GHTPLHVAVI HKDVEMVRLL RDAGADLDKP
160 170 180 190 200
EPTCGRSPLH LAVEAQAADV LELLLRAGAN PAARMYGGRT PLGSAMLRPN
210 220 230 240 250
PILARLLRAH GAPEPEGEDE KSGPCSSSSD SDSGDEGDEY DDIVVHSSRS
260 270
QTRLPPTPAS KPLPDDPRPV
Length:270
Mass (Da):29,145
Last modified:October 29, 2014 - v2
Checksum:iAB74380323EA4CC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011455 Genomic DNA. No translation available.
RefSeqiNP_001230045.1. NM_001243116.1.
UniGeneiHs.9731.

Genome annotation databases

EnsembliENST00000392079; ENSP00000375929; ENSG00000104825.
GeneIDi4793.
UCSCiuc010egk.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011455 Genomic DNA. No translation available.
RefSeqiNP_001230045.1. NM_001243116.1.
UniGeneiHs.9731.

3D structure databases

ProteinModelPortaliG5E9C2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000312988.

Proteomic databases

PaxDbiG5E9C2.
PeptideAtlasiG5E9C2.
PRIDEiG5E9C2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000392079; ENSP00000375929; ENSG00000104825.
GeneIDi4793.
UCSCiuc010egk.3. human.

Organism-specific databases

CTDi4793.
HGNCiHGNC:7798. NFKBIB.
OpenTargetsiENSG00000104825.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0504. Eukaryota.
COG0666. LUCA.
GeneTreeiENSGT00550000074527.

Miscellaneous databases

ChiTaRSiNFKBIB. human.
GenomeRNAii4793.

Gene expression databases

BgeeiENSG00000104825.
ExpressionAtlasiG5E9C2. baseline and differential.

Family and domain databases

Gene3Di1.25.40.20. 2 hits.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
[Graphical view]
PfamiPF12796. Ank_2. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 5 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG5E9C2_HUMAN
AccessioniPrimary (citable) accession number: G5E9C2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: October 29, 2014
Last modified: November 2, 2016
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.