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Protein
Submitted name:

Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6C, isoform CRA_a

Gene

Sema6c

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Sema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6C, isoform CRA_aImported
Submitted name:
Semaphorin-6CImported
Gene namesi
Name:Sema6cImported
ORF Names:mCG_13711Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1338032 Sema6c

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei598 – 622HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_501409197526 – 923Sequence analysisAdd BLAST898

Proteomic databases

MaxQBiG5E8N4

Expressioni

Gene expression databases

BgeeiENSMUSG00000038777

Structurei

3D structure databases

SMRiG5E8N4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 477SemaInterPro annotationAdd BLAST447

Sequence similaritiesi

Belongs to the semaphorin family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000119134
TreeFamiTF316102

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR001627 Semap_dom
IPR036352 Semap_dom_sf
IPR027231 Semaphorin
IPR015514 Semaphorin_6C
IPR015943 WD40/YVTN_repeat-like_dom_sf
PANTHERiPTHR11036 PTHR11036, 2 hits
PTHR11036:SF11 PTHR11036:SF11, 2 hits
PfamiView protein in Pfam
PF01403 Sema, 2 hits
SMARTiView protein in SMART
SM00630 Sema, 1 hit
SUPFAMiSSF101912 SSF101912, 1 hit
PROSITEiView protein in PROSITE
PS51004 SEMA, 1 hit

Sequencei

Sequence statusi: Complete.

G5E8N4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRAPHSMPL LLLLLLLSSL PQAQAAFPQD PTPLLTSDLQ GASPSSWFRG
60 70 80 90 100
LEDDAVAAEL GLDFQRFLTL NRTLLVAARD HVFSFDLQAQ EEGEGLVPNK
110 120 130 140 150
FLTWRSQDME NCAVRGKLTD ECYNYIRVLV PWNSQTLLAC GTNSFSPMCR
160 170 180 190 200
SYGITSLQQE GEELSGQARC PFDATQSTVA IFAEPHFVYA LEHGEHVYFF
210 220 230 240 250
FREVSVEDAR LGRVQFSRVA RVCKRDMGGS PRALDRHWTS FLKLRLNCSV
260 270 280 290 300
PGDSTFYFDV LQSLTGPVNL HGRSALFGVF TTQTNSIPGS AVCAFYLDDI
310 320 330 340 350
ERGFEGKFKE QRSLDGAWTP VSEDKVPSPR PGSCAGVGAA ASFSSSQDLP
360 370 380 390 400
DDVLLFIKAH PLLDPAVPPA THQPLLTLTS RALLTQVAVD GMAGPHRNTT
410 420 430 440 450
VLFLGSNDGT VLKVLPPGGQ SLGSEPIVLE EIDAYSHARC SGKRSPRAAR
460 470 480 490 500
RIIGLELDTE GHRLFVAFPG CIVYLSLSRC ARHGACQRSC LASLDPYCGW
510 520 530 540 550
HRSRGCMSIR GPGGTDVDLT GNQESTEHGD CQDGATGSQS GPGDSAYVLL
560 570 580 590 600
GPGPSPETPS SPSDAQQGPQ SSTLGAHTQG VRRDLSPASA SRSIPIPLLL
610 620 630 640 650
ACVAAAFALG ASVSGLLVSC ACRRANRRRS KDIETPGLPR PLSLRSLARL
660 670 680 690 700
HGGGPEPPPP PKDGDAAQTP QLYTTFLPPP DGGSPPELAC LPTPETTPEL
710 720 730 740 750
PVKHLRASGG PWEWNQNGNN ASEGPGRPPR GCSGAGGPAP RVLVRPPPPG
760 770 780 790 800
CPGQAVEVTT LEELLRYLHG PQPPRKGSEP LASAPFTSRP PASEPGASLF
810 820 830 840 850
VDSSPMPRDG VPPLRLDVPP EGKRAAPSGR PALSAPAPRL GVGGSRRLPF
860 870 880 890 900
PTHRAPPGLL TRVPSGGPAR YSGGPGRHLL YLGRPEGHRG RSLKRVDVKS
910 920
PLSPKPPLAS PPQPAPHGGH FNF
Length:923
Mass (Da):98,264
Last modified:December 14, 2011 - v1
Checksum:i1B081DD77BE428E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC131769 Genomic DNA No translation available.
AC140190 Genomic DNA No translation available.
CH466620 Genomic DNA Translation: EDL38780.1
UniGeneiMm.23662

Genome annotation databases

EnsembliENSMUST00000107217; ENSMUSP00000102835; ENSMUSG00000038777
UCSCiuc008qil.2 mouse

Similar proteinsi

Entry informationi

Entry nameiG5E8N4_MOUSE
AccessioniPrimary (citable) accession number: G5E8N4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 25, 2018
This is version 62 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health