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Protein
Submitted name:

Cytotoxic granule-associated RNA binding protein 1, isoform CRA_f

Gene

Tia1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cytotoxic granule-associated RNA binding protein 1, isoform CRA_fImported
Submitted name:
Nucleolysin TIA-1Imported
Gene namesi
Name:Tia1Imported
ORF Names:mCG_130509Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:107914 Tia1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiG5E8L2
PeptideAtlasiG5E8L2

Expressioni

Gene expression databases

BgeeiENSMUSG00000071337

Structurei

3D structure databases

SMRiG5E8L2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 83RRMInterPro annotationAdd BLAST77
Domaini95 – 173RRMInterPro annotationAdd BLAST79
Domaini203 – 275RRMInterPro annotationAdd BLAST73

Phylogenomic databases

eggNOGiKOG0148 Eukaryota
ENOG410XQ8U LUCA
GeneTreeiENSGT00910000144106

Family and domain databases

CDDicd12615 RRM1_TIA1, 1 hit
cd12618 RRM2_TIA1, 1 hit
cd12621 RRM3_TIA1, 1 hit
Gene3Di3.30.70.330, 3 hits
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR003954 RRM_dom_euk
IPR034827 TIA-1_RRM1
IPR034830 TIA1_RRM2
IPR034832 TIA1_RRM3
PfamiView protein in Pfam
PF00076 RRM_1, 3 hits
SMARTiView protein in SMART
SM00360 RRM, 3 hits
SM00361 RRM_1, 3 hits
SUPFAMiSSF54928 SSF54928, 3 hits
PROSITEiView protein in PROSITE
PS50102 RRM, 3 hits

Sequencei

Sequence statusi: Complete.

G5E8L2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDEMPKTLY VGNLSRDVTE ALILQLFSQI GPCKNCKMIM DTAGNDPYCF
60 70 80 90 100
VEFHEHRHAA AALAAMNGRK IMGKEVKVNW ATTPSSQKKD TSNHFHVFVG
110 120 130 140 150
DLSPEITTED IKAAFAPFGR ISDARVVKDM ATGKSKGYGF VSFFNKWDAE
160 170 180 190 200
NAIQQMGGQW LGGRQIRTNW ATRKPPAPKS TYESNTKQLS YDEVVSQSSP
210 220 230 240 250
NNCTVYCGGV TSGLTEQLMR QTFSPFGQIM EIRVFPDKGY SFVRFSSHES
260 270 280 290 300
AAHAIVSVNG TTIEGHVVKC YWGKETLDMI NPVQQQNQIG YPPTYGQWGQ
310 320 330 340 350
WYGNAQQIGQ YVPNGWQVPA YGVYGQPWSQ QGFNQTQSSA PWMGPNYSVP
360 370
PPQGQNGSML PSQPAGYRVA GYETQ
Length:375
Mass (Da):41,638
Last modified:December 14, 2011 - v1
Checksum:i1811A08F4E47467D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153374 Genomic DNA No translation available.
CH466523 Genomic DNA Translation: EDK99172.1
RefSeqiXP_006505952.1, XM_006505889.2
UniGeneiMm.333219

Genome annotation databases

EnsembliENSMUST00000095752; ENSMUSP00000093424; ENSMUSG00000071337
GeneIDi21841

Similar proteinsi

Entry informationi

Entry nameiG5E8L2_MOUSE
AccessioniPrimary (citable) accession number: G5E8L2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 25, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health