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Protein
Submitted name:

Cytotoxic granule-associated RNA binding protein 1, isoform CRA_f

Gene

Tia1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cytotoxic granule-associated RNA binding protein 1, isoform CRA_fImported
Submitted name:
Nucleolysin TIA-1Imported
Gene namesi
Name:Tia1Imported
ORF Names:mCG_130509Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:107914. Tia1.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSMUSG00000071337.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 83RRM (RNA recognition motif)InterPro annotationAdd BLAST77
Domaini95 – 173RRM (RNA recognition motif)InterPro annotationAdd BLAST79
Domaini203 – 275RRM (RNA recognition motif)InterPro annotationAdd BLAST73

Phylogenomic databases

eggNOGiKOG0148. Eukaryota.
ENOG410XQ8U. LUCA.
GeneTreeiENSGT00870000136413.

Family and domain databases

CDDicd12615. RRM1_TIA1. 1 hit.
cd12618. RRM2_TIA1. 1 hit.
cd12621. RRM3_TIA1. 1 hit.
InterProiView protein in InterPro
IPR000504. RRM_dom.
IPR003954. RRM_dom_euk.
IPR034827. TIA-1_RRM1.
IPR034830. TIA1_RRM2.
IPR034832. TIA1_RRM3.
PfamiView protein in Pfam
PF00076. RRM_1. 3 hits.
SMARTiView protein in SMART
SM00360. RRM. 3 hits.
SM00361. RRM_1. 3 hits.
SUPFAMiSSF54928. SSF54928. 3 hits.
PROSITEiView protein in PROSITE
PS50102. RRM. 3 hits.

Sequencei

Sequence statusi: Complete.

G5E8L2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDEMPKTLY VGNLSRDVTE ALILQLFSQI GPCKNCKMIM DTAGNDPYCF
60 70 80 90 100
VEFHEHRHAA AALAAMNGRK IMGKEVKVNW ATTPSSQKKD TSNHFHVFVG
110 120 130 140 150
DLSPEITTED IKAAFAPFGR ISDARVVKDM ATGKSKGYGF VSFFNKWDAE
160 170 180 190 200
NAIQQMGGQW LGGRQIRTNW ATRKPPAPKS TYESNTKQLS YDEVVSQSSP
210 220 230 240 250
NNCTVYCGGV TSGLTEQLMR QTFSPFGQIM EIRVFPDKGY SFVRFSSHES
260 270 280 290 300
AAHAIVSVNG TTIEGHVVKC YWGKETLDMI NPVQQQNQIG YPPTYGQWGQ
310 320 330 340 350
WYGNAQQIGQ YVPNGWQVPA YGVYGQPWSQ QGFNQTQSSA PWMGPNYSVP
360 370
PPQGQNGSML PSQPAGYRVA GYETQ
Length:375
Mass (Da):41,638
Last modified:December 14, 2011 - v1
Checksum:i1811A08F4E47467D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC153374 Genomic DNA. No translation available.
CH466523 Genomic DNA. Translation: EDK99172.1.
RefSeqiXP_006505952.1. XM_006505889.2.
UniGeneiMm.333219.

Genome annotation databases

EnsembliENSMUST00000095752; ENSMUSP00000093424; ENSMUSG00000071337.
GeneIDi21841.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiG5E8L2_MOUSE
AccessioniPrimary (citable) accession number: G5E8L2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: July 5, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported