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G5E8D5

- G5E8D5_MOUSE

UniProt

G5E8D5 - G5E8D5_MOUSE

Protein
Submitted name:

Metabotropic glutamate receptor 7

Gene

Grm7

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium channel regulator activity Source: MGI
    2. group III metabotropic glutamate receptor activity Source: RefGenome

    GO - Biological processi

    1. adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway Source: RefGenome
    2. adult behavior Source: MGI
    3. associative learning Source: MGI
    4. behavioral fear response Source: MGI
    5. conditioned taste aversion Source: MGI
    6. memory Source: MGI
    7. multicellular organismal response to stress Source: MGI
    8. neurological system process Source: MGI
    9. regulation of synaptic transmission, glutamatergic Source: RefGenome
    10. short-term memory Source: MGI
    11. transmission of nerve impulse Source: MGI

    Keywords - Molecular functioni

    G-protein coupled receptorSAAS annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Metabotropic glutamate receptor 7Imported
    Gene namesi
    Name:Grm7Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 6

    Organism-specific databases

    MGIiMGI:1351344. Grm7.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of plasma membrane Source: RefGenome
    2. receptor complex Source: MGI

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiG5E8D5.
    BgeeiG5E8D5.

    Structurei

    3D structure databases

    ProteinModelPortaliG5E8D5.
    SMRiG5E8D5. Positions 40-580.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117581.
    KOiK04608.
    OMAiRTGCRSI.
    OrthoDBiEOG7Z0JXG.

    Family and domain databases

    InterProiIPR001828. ANF_lig-bd_rcpt.
    IPR000337. GPCR_3.
    IPR011500. GPCR_3_9-Cys_dom.
    IPR017978. GPCR_3_C.
    IPR017979. GPCR_3_CS.
    IPR000162. GPCR_3_mtglu_rcpt.
    IPR001883. GPCR_3_mtglu_rcpt_7.
    IPR028082. Peripla_BP_I.
    [Graphical view]
    PfamiPF00003. 7tm_3. 1 hit.
    PF01094. ANF_receptor. 1 hit.
    PF07562. NCD3G. 1 hit.
    [Graphical view]
    PRINTSiPR00248. GPCRMGR.
    PR01057. MTABOTROPC7R.
    PR00593. MTABOTROPICR.
    SUPFAMiSSF53822. SSF53822. 1 hit.
    PROSITEiPS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
    PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
    PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
    PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G5E8D5-1 [UniParc]FASTAAdd to Basket

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    MVQLGKLLRV LTLMKFPCCV LEVLLCVLAA AARGQEMYAP HSIRIEGDVT    50
    LGGLFPVHAK GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT 100
    LGARILDTCS RDTYALEQSL TFVQALIQKD TSDVRCTNGE PPVFVKPEKV 150
    VGVIGASGSS VSIMVANILR LFQIPQISYA STAPELSDDR RYDFFSRVVP 200
    PDSFQAQAMV DIVKALGWNY VSTLASEGSY GEKGVESFTQ ISKEAGGLCI 250
    AQSVRIPQER KDRTIDFDRI IKQLLDTPNS RAVVIFANDE DIKQILAAAK 300
    RADQVGHFLW VGSDSWGSKI NPLHQHEDIA EGAITIQPKR ATVEGFDAYF 350
    TSRTLENNRR NVWFAEYWEE NFNCKLTISG SKKEDTDRKC TGQERIGKDS 400
    NYEQEGKVQF VIDAVYAMAH ALHHMNKDLC ADYRGVCPEM EQAGGKKLLK 450
    YIRNVNFNGS AGTPVMFNKN GDAPGRYDIF QYQTTNTTNP GYRLIGQWTD 500
    ELQLNIEDMQ WGKGVREIPP SVCTLPCKPG QRKKTQKGTP CCWTCEPCDG 550
    YQYQFDEMTC QHCPYDQRPN ENRTGCQNIP IIKLEWHSPW AVIPVFLAML 600
    GIIATIFVMA TFIRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP 650
    DVAVCSFRRV FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT 700
    SQLAITSSLI SVQLLGVFIW FGVDPPNIII DYDEHKTMNP EQARGVLKCD 750
    ITDLQIICSL GYSILLMVTC TVYAIKTRGV PENFNEAKPI GFTMYTTCIV 800
    WLAFIPIFFG TAQSAEKLYI QTTTLTISMN LSASVALGML YMPKVYIIIF 850
    HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNN 900
    CIPPVRKSVQ KSVTWYTIPP TV 922
    Length:922
    Mass (Da):103,038
    Last modified:December 14, 2011 - v1
    Checksum:i3FDA0C7B2724716E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC114643 Genomic DNA. No translation available.
    AC121894 Genomic DNA. No translation available.
    AC125046 Genomic DNA. No translation available.
    AC132394 Genomic DNA. No translation available.
    AC142264 Genomic DNA. No translation available.
    AC165365 Genomic DNA. No translation available.
    AC169981 Genomic DNA. No translation available.
    AC169984 Genomic DNA. No translation available.
    RefSeqiXP_006505360.1. XM_006505297.1.
    XP_006505361.1. XM_006505298.1.
    XP_006505362.1. XM_006505299.1.
    UniGeneiMm.240881.

    Genome annotation databases

    EnsembliENSMUST00000071076; ENSMUSP00000064404; ENSMUSG00000056755.
    GeneIDi108073.
    KEGGimmu:108073.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC114643 Genomic DNA. No translation available.
    AC121894 Genomic DNA. No translation available.
    AC125046 Genomic DNA. No translation available.
    AC132394 Genomic DNA. No translation available.
    AC142264 Genomic DNA. No translation available.
    AC165365 Genomic DNA. No translation available.
    AC169981 Genomic DNA. No translation available.
    AC169984 Genomic DNA. No translation available.
    RefSeqi XP_006505360.1. XM_006505297.1.
    XP_006505361.1. XM_006505298.1.
    XP_006505362.1. XM_006505299.1.
    UniGenei Mm.240881.

    3D structure databases

    ProteinModelPortali G5E8D5.
    SMRi G5E8D5. Positions 40-580.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000071076 ; ENSMUSP00000064404 ; ENSMUSG00000056755 .
    GeneIDi 108073.
    KEGGi mmu:108073.

    Organism-specific databases

    CTDi 2917.
    MGIi MGI:1351344. Grm7.

    Phylogenomic databases

    GeneTreei ENSGT00750000117581.
    KOi K04608.
    OMAi RTGCRSI.
    OrthoDBi EOG7Z0JXG.

    Miscellaneous databases

    ChiTaRSi GRM7. mouse.
    NextBioi 35561203.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi G5E8D5.
    Bgeei G5E8D5.

    Family and domain databases

    InterProi IPR001828. ANF_lig-bd_rcpt.
    IPR000337. GPCR_3.
    IPR011500. GPCR_3_9-Cys_dom.
    IPR017978. GPCR_3_C.
    IPR017979. GPCR_3_CS.
    IPR000162. GPCR_3_mtglu_rcpt.
    IPR001883. GPCR_3_mtglu_rcpt_7.
    IPR028082. Peripla_BP_I.
    [Graphical view ]
    Pfami PF00003. 7tm_3. 1 hit.
    PF01094. ANF_receptor. 1 hit.
    PF07562. NCD3G. 1 hit.
    [Graphical view ]
    PRINTSi PR00248. GPCRMGR.
    PR01057. MTABOTROPC7R.
    PR00593. MTABOTROPICR.
    SUPFAMi SSF53822. SSF53822. 1 hit.
    PROSITEi PS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
    PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
    PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
    PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (OCT-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiG5E8D5_MOUSE
    AccessioniPrimary (citable) accession number: G5E8D5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3