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G5E8D5

- G5E8D5_MOUSE

UniProt

G5E8D5 - G5E8D5_MOUSE

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Protein
Submitted name:

Metabotropic glutamate receptor 7

Gene

Grm7

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium channel regulator activity Source: MGI
  2. group III metabotropic glutamate receptor activity Source: RefGenome

GO - Biological processi

  1. adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway Source: RefGenome
  2. adult behavior Source: MGI
  3. associative learning Source: MGI
  4. behavioral fear response Source: MGI
  5. conditioned taste aversion Source: MGI
  6. memory Source: MGI
  7. multicellular organismal response to stress Source: MGI
  8. neurological system process Source: MGI
  9. regulation of synaptic transmission, glutamatergic Source: RefGenome
  10. short-term memory Source: MGI
  11. transmission of nerve impulse Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Metabotropic glutamate receptor 7Imported
Gene namesi
Name:Grm7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 6

Organism-specific databases

MGIiMGI:1351344. Grm7.

Subcellular locationi

GO - Cellular componenti

  1. integral component of plasma membrane Source: RefGenome
  2. receptor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiG5E8D5.
ExpressionAtlasiG5E8D5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliG5E8D5.
SMRiG5E8D5. Positions 40-691, 701-855.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118884.
KOiK04608.
OMAiRTGCRSI.
OrthoDBiEOG7Z0JXG.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR001883. GPCR_3_mtglu_rcpt_7.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01057. MTABOTROPC7R.
PR00593. MTABOTROPICR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5E8D5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVQLGKLLRV LTLMKFPCCV LEVLLCVLAA AARGQEMYAP HSIRIEGDVT
60 70 80 90 100
LGGLFPVHAK GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT
110 120 130 140 150
LGARILDTCS RDTYALEQSL TFVQALIQKD TSDVRCTNGE PPVFVKPEKV
160 170 180 190 200
VGVIGASGSS VSIMVANILR LFQIPQISYA STAPELSDDR RYDFFSRVVP
210 220 230 240 250
PDSFQAQAMV DIVKALGWNY VSTLASEGSY GEKGVESFTQ ISKEAGGLCI
260 270 280 290 300
AQSVRIPQER KDRTIDFDRI IKQLLDTPNS RAVVIFANDE DIKQILAAAK
310 320 330 340 350
RADQVGHFLW VGSDSWGSKI NPLHQHEDIA EGAITIQPKR ATVEGFDAYF
360 370 380 390 400
TSRTLENNRR NVWFAEYWEE NFNCKLTISG SKKEDTDRKC TGQERIGKDS
410 420 430 440 450
NYEQEGKVQF VIDAVYAMAH ALHHMNKDLC ADYRGVCPEM EQAGGKKLLK
460 470 480 490 500
YIRNVNFNGS AGTPVMFNKN GDAPGRYDIF QYQTTNTTNP GYRLIGQWTD
510 520 530 540 550
ELQLNIEDMQ WGKGVREIPP SVCTLPCKPG QRKKTQKGTP CCWTCEPCDG
560 570 580 590 600
YQYQFDEMTC QHCPYDQRPN ENRTGCQNIP IIKLEWHSPW AVIPVFLAML
610 620 630 640 650
GIIATIFVMA TFIRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP
660 670 680 690 700
DVAVCSFRRV FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT
710 720 730 740 750
SQLAITSSLI SVQLLGVFIW FGVDPPNIII DYDEHKTMNP EQARGVLKCD
760 770 780 790 800
ITDLQIICSL GYSILLMVTC TVYAIKTRGV PENFNEAKPI GFTMYTTCIV
810 820 830 840 850
WLAFIPIFFG TAQSAEKLYI QTTTLTISMN LSASVALGML YMPKVYIIIF
860 870 880 890 900
HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNN
910 920
CIPPVRKSVQ KSVTWYTIPP TV
Length:922
Mass (Da):103,038
Last modified:December 14, 2011 - v1
Checksum:i3FDA0C7B2724716E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114643 Genomic DNA. No translation available.
AC121894 Genomic DNA. No translation available.
AC125046 Genomic DNA. No translation available.
AC132394 Genomic DNA. No translation available.
AC142264 Genomic DNA. No translation available.
AC165365 Genomic DNA. No translation available.
AC169981 Genomic DNA. No translation available.
AC169984 Genomic DNA. No translation available.
RefSeqiXP_006505360.1. XM_006505297.1.
XP_006505361.1. XM_006505298.1.
XP_006505362.1. XM_006505299.1.
UniGeneiMm.240881.

Genome annotation databases

EnsembliENSMUST00000071076; ENSMUSP00000064404; ENSMUSG00000056755.
GeneIDi108073.
KEGGimmu:108073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC114643 Genomic DNA. No translation available.
AC121894 Genomic DNA. No translation available.
AC125046 Genomic DNA. No translation available.
AC132394 Genomic DNA. No translation available.
AC142264 Genomic DNA. No translation available.
AC165365 Genomic DNA. No translation available.
AC169981 Genomic DNA. No translation available.
AC169984 Genomic DNA. No translation available.
RefSeqi XP_006505360.1. XM_006505297.1.
XP_006505361.1. XM_006505298.1.
XP_006505362.1. XM_006505299.1.
UniGenei Mm.240881.

3D structure databases

ProteinModelPortali G5E8D5.
SMRi G5E8D5. Positions 40-691, 701-855.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000071076 ; ENSMUSP00000064404 ; ENSMUSG00000056755 .
GeneIDi 108073.
KEGGi mmu:108073.

Organism-specific databases

CTDi 2917.
MGIi MGI:1351344. Grm7.

Phylogenomic databases

GeneTreei ENSGT00760000118884.
KOi K04608.
OMAi RTGCRSI.
OrthoDBi EOG7Z0JXG.

Miscellaneous databases

NextBioi 35561203.
SOURCEi Search...

Gene expression databases

Bgeei G5E8D5.
ExpressionAtlasi G5E8D5. baseline and differential.

Family and domain databases

InterProi IPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR001883. GPCR_3_mtglu_rcpt_7.
IPR028082. Peripla_BP_I.
[Graphical view ]
Pfami PF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view ]
PRINTSi PR00248. GPCRMGR.
PR01057. MTABOTROPC7R.
PR00593. MTABOTROPICR.
SUPFAMi SSF53822. SSF53822. 1 hit.
PROSITEi PS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (OCT-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG5E8D5_MOUSE
AccessioniPrimary (citable) accession number: G5E8D5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: November 26, 2014
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3