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G5E8D5

- G5E8D5_MOUSE

UniProt

G5E8D5 - G5E8D5_MOUSE

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Protein
Submitted name:

Metabotropic glutamate receptor 7

Gene
Grm7
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. calcium channel regulator activity Source: MGI
  2. group III metabotropic glutamate receptor activity Source: RefGenome

GO - Biological processi

  1. adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway Source: RefGenome
  2. adult behavior Source: MGI
  3. associative learning Source: MGI
  4. behavioral fear response Source: MGI
  5. conditioned taste aversion Source: MGI
  6. memory Source: MGI
  7. multicellular organismal response to stress Source: MGI
  8. neurological system process Source: MGI
  9. regulation of synaptic transmission, glutamatergic Source: RefGenome
  10. short-term memory Source: MGI
  11. transmission of nerve impulse Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotations, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Metabotropic glutamate receptor 7Imported
Gene namesi
Name:Grm7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 6

Organism-specific databases

MGIiMGI:1351344. Grm7.

Subcellular locationi

GO - Cellular componenti

  1. integral component of plasma membrane Source: RefGenome
  2. receptor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotations, Membrane

Expressioni

Gene expression databases

ArrayExpressiG5E8D5.
BgeeiG5E8D5.

Structurei

3D structure databases

ProteinModelPortaliG5E8D5.
SMRiG5E8D5. Positions 40-856.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00750000117581.
KOiK04608.
OMAiRTGCRSI.
OrthoDBiEOG7Z0JXG.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR001883. GPCR_3_mtglu_rcpt_7.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01057. MTABOTROPC7R.
PR00593. MTABOTROPICR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5E8D5-1 [UniParc]FASTAAdd to Basket

« Hide

MVQLGKLLRV LTLMKFPCCV LEVLLCVLAA AARGQEMYAP HSIRIEGDVT    50
LGGLFPVHAK GPSGVPCGDI KRENGIHRLE AMLYALDQIN SDPNLLPNVT 100
LGARILDTCS RDTYALEQSL TFVQALIQKD TSDVRCTNGE PPVFVKPEKV 150
VGVIGASGSS VSIMVANILR LFQIPQISYA STAPELSDDR RYDFFSRVVP 200
PDSFQAQAMV DIVKALGWNY VSTLASEGSY GEKGVESFTQ ISKEAGGLCI 250
AQSVRIPQER KDRTIDFDRI IKQLLDTPNS RAVVIFANDE DIKQILAAAK 300
RADQVGHFLW VGSDSWGSKI NPLHQHEDIA EGAITIQPKR ATVEGFDAYF 350
TSRTLENNRR NVWFAEYWEE NFNCKLTISG SKKEDTDRKC TGQERIGKDS 400
NYEQEGKVQF VIDAVYAMAH ALHHMNKDLC ADYRGVCPEM EQAGGKKLLK 450
YIRNVNFNGS AGTPVMFNKN GDAPGRYDIF QYQTTNTTNP GYRLIGQWTD 500
ELQLNIEDMQ WGKGVREIPP SVCTLPCKPG QRKKTQKGTP CCWTCEPCDG 550
YQYQFDEMTC QHCPYDQRPN ENRTGCQNIP IIKLEWHSPW AVIPVFLAML 600
GIIATIFVMA TFIRYNDTPI VRASGRELSY VLLTGIFLCY IITFLMIAKP 650
DVAVCSFRRV FLGLGMCISY AALLTKTNRI YRIFEQGKKS VTAPRLISPT 700
SQLAITSSLI SVQLLGVFIW FGVDPPNIII DYDEHKTMNP EQARGVLKCD 750
ITDLQIICSL GYSILLMVTC TVYAIKTRGV PENFNEAKPI GFTMYTTCIV 800
WLAFIPIFFG TAQSAEKLYI QTTTLTISMN LSASVALGML YMPKVYIIIF 850
HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNN 900
CIPPVRKSVQ KSVTWYTIPP TV 922
Length:922
Mass (Da):103,038
Last modified:December 14, 2011 - v1
Checksum:i3FDA0C7B2724716E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC114643 Genomic DNA. No translation available.
AC121894 Genomic DNA. No translation available.
AC125046 Genomic DNA. No translation available.
AC132394 Genomic DNA. No translation available.
AC142264 Genomic DNA. No translation available.
AC165365 Genomic DNA. No translation available.
AC169981 Genomic DNA. No translation available.
AC169984 Genomic DNA. No translation available.
RefSeqiXP_006505360.1. XM_006505297.1.
XP_006505361.1. XM_006505298.1.
XP_006505362.1. XM_006505299.1.
UniGeneiMm.240881.

Genome annotation databases

EnsembliENSMUST00000071076; ENSMUSP00000064404; ENSMUSG00000056755.
GeneIDi108073.
KEGGimmu:108073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC114643 Genomic DNA. No translation available.
AC121894 Genomic DNA. No translation available.
AC125046 Genomic DNA. No translation available.
AC132394 Genomic DNA. No translation available.
AC142264 Genomic DNA. No translation available.
AC165365 Genomic DNA. No translation available.
AC169981 Genomic DNA. No translation available.
AC169984 Genomic DNA. No translation available.
RefSeqi XP_006505360.1. XM_006505297.1.
XP_006505361.1. XM_006505298.1.
XP_006505362.1. XM_006505299.1.
UniGenei Mm.240881.

3D structure databases

ProteinModelPortali G5E8D5.
SMRi G5E8D5. Positions 40-856.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000071076 ; ENSMUSP00000064404 ; ENSMUSG00000056755 .
GeneIDi 108073.
KEGGi mmu:108073.

Organism-specific databases

CTDi 2917.
MGIi MGI:1351344. Grm7.

Phylogenomic databases

GeneTreei ENSGT00750000117581.
KOi K04608.
OMAi RTGCRSI.
OrthoDBi EOG7Z0JXG.

Miscellaneous databases

ChiTaRSi GRM7. mouse.
NextBioi 35561203.
SOURCEi Search...

Gene expression databases

ArrayExpressi G5E8D5.
Bgeei G5E8D5.

Family and domain databases

InterProi IPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR001883. GPCR_3_mtglu_rcpt_7.
IPR028082. Peripla_BP_I.
[Graphical view ]
Pfami PF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view ]
PRINTSi PR00248. GPCRMGR.
PR01057. MTABOTROPC7R.
PR00593. MTABOTROPICR.
SUPFAMi SSF53822. SSF53822. 1 hit.
PROSITEi PS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (OCT-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG5E8D5_MOUSE
AccessioniPrimary (citable) accession number: G5E8D5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: July 9, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi