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G5E871

- G5E871_MOUSE

UniProt

G5E871 - G5E871_MOUSE

Protein
Submitted name:

Neuromedin U receptor 1

Gene

Nmur1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. neuromedin U receptor activity Source: Ensembl
    2. neuropeptide receptor activity Source: MGI

    GO - Biological processi

    1. activation of phospholipase C activity Source: Ensembl
    2. calcium ion transport Source: Ensembl
    3. calcium-mediated signaling Source: Ensembl
    4. chloride transport Source: Ensembl
    5. inositol phosphate-mediated signaling Source: Ensembl
    6. neuropeptide signaling pathway Source: MGI
    7. phospholipase C-activating G-protein coupled receptor signaling pathway Source: Ensembl
    8. smooth muscle contraction Source: Ensembl

    Keywords - Molecular functioni

    G-protein coupled receptorUniRule annotation, Receptor, Transducer

    Enzyme and pathway databases

    ReactomeiREACT_207651. G alpha (q) signalling events.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Neuromedin U receptor 1Imported
    Submitted name:
    Neuromedin-U receptor 1Imported
    Gene namesi
    Name:Nmur1Imported
    ORF Names:mCG_8508Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 1

    Organism-specific databases

    MGIiMGI:1341898. Nmur1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of plasma membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.UniRule annotation

    Keywords - Domaini

    TransmembraneUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00700000104070.
    OMAiLVILRHK.
    OrthoDBiEOG7T4MK9.
    TreeFamiTF318522.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR005390. NeuromedU_rcpt.
    IPR005391. NeuromedU_rcpt_1.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR01565. NEUROMEDINUR.
    PR01566. NEUROMEDNU1R.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G5E871-1 [UniParc]FASTAAdd to Basket

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    LVCNISEFKW PYQPEDLNLT DEALRLKYLG PQQMKQFVPI CVTYLLIFVV    50
    GTLGNGLTCT VILRNKTMRT PTNFYLFSLA VSDMLVLLVG LPLELYEMQQ 100
    NYPFQLGASA CYFRILLLET VCLASVLNVT ALSVERYVAV VRPLQAKSVM 150
    TRAHVRRMVG AIWVLATLFS LPNTSLHGLS QLTVPCRGPV PDSAICSLVG 200
    PMDFYKLVVL TTALLFFCLP MVTISVLYLL IGLRLRRERM LLQVEVKGRK 250
    TAATQETSHR RIQLQDRGRR QVTKMLFALV VVFGICWAPF HADRIMWSLV 300
    YGHSTEGLHL AYQCVHIASG IFFYLGSAAN PVLYSLMSTR FRETFLQALG 350
    LGTQCCHRRQ PYHGSHNHIR LTTGSTLCDV GHRNSRDEPL AVNEDPGCQQ 400
    ETDPS 405
    Length:405
    Mass (Da):45,592
    Last modified:December 14, 2011 - v1
    Checksum:iAA4B1DD2612C215A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102609 Genomic DNA. No translation available.
    CH466520 Genomic DNA. Translation: EDL40217.1.
    UniGeneiMm.389159.

    Genome annotation databases

    EnsembliENSMUST00000027440; ENSMUSP00000027440; ENSMUSG00000026237.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC102609 Genomic DNA. No translation available.
    CH466520 Genomic DNA. Translation: EDL40217.1 .
    UniGenei Mm.389159.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000027440 ; ENSMUSP00000027440 ; ENSMUSG00000026237 .

    Organism-specific databases

    MGIi MGI:1341898. Nmur1.

    Phylogenomic databases

    GeneTreei ENSGT00700000104070.
    OMAi LVILRHK.
    OrthoDBi EOG7T4MK9.
    TreeFami TF318522.

    Enzyme and pathway databases

    Reactomei REACT_207651. G alpha (q) signalling events.

    Miscellaneous databases

    NextBioi 35561194.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR005390. NeuromedU_rcpt.
    IPR005391. NeuromedU_rcpt_1.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR01565. NEUROMEDINUR.
    PR01566. NEUROMEDNU1R.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (OCT-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiG5E871_MOUSE
    AccessioniPrimary (citable) accession number: G5E871
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3