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Protein
Submitted name:

Prostaglandin G/H synthase 2

Gene

GW7_07100

Organism
Heterocephalus glaber (Naked mole rat)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. peroxidase activity Source: InterPro
  3. prostaglandin-endoperoxide synthase activity Source: InterPro

GO - Biological processi

  1. cyclooxygenase pathway Source: InterPro
  2. inflammatory response Source: InterPro
  3. regulation of blood pressure Source: InterPro
  4. response to oxidative stress Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Prostaglandin G/H synthase 2Imported
Gene namesi
ORF Names:GW7_07100Imported
OrganismiHeterocephalus glaber (Naked mole rat)Imported
Taxonomic identifieri10181 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricognathiBathyergidaeHeterocephalus
ProteomesiUP000006813: Unassembled WGS sequence

Family & Domainsi

Phylogenomic databases

InParanoidiG5C6B9.
KOiK11987.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
PfamiPF03098. An_peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SMARTiSM00181. EGF. 1 hit.
[Graphical view]
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5C6B9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLARALLLCA ALALCQAASP CCSNPCQNRG ECLSVGFDRY QCDCTRTGFY
60 70 80 90 100
GENCTTPEFL TRIKLLLKPT PNTVHYILTH FKGVWNIVNN IPFLRNSIMR
110 120 130 140 150
YVLTSRSHLI DSPPTYNSDY GYRSWEAFSN LSYYTRVLPP VADDCPTPMG
160 170 180 190 200
VKGKKELPDS NKVLEKVLLR RKFIPDPQGT NMMFAFFAQH FTHQFFKSDP
210 220 230 240 250
KRGPAFTTGL AHGVDLSHVY GETLDRQHKL RLFRDGKMKY QIIDGEMYPP
260 270 280 290 300
TVKDTQVQMI YPPHTPEHLR FAVGQEVFGL VPGLMMYATI WLREHNRVCD
310 320 330 340 350
VLKQEHPEWD DERLFQTSRL ILIGETIKIV IEDYVQHLSG YHFKLKFDPE
360 370 380 390 400
LLFNQQFQYQ NRIASEFNTL YHWHPLLPDT FQIHDQEYNF QQFLYNNSML
410 420 430 440 450
VEHGLTQFVE SFTKQIAGRV AGGRNVPLAV QKVAKASIDH SRNMKYQSLN
460 470 480 490 500
EYRKHFLLKP YASFEDLTGE KEMAAELEAL YGDIDAVELY PALLVEKPRP
510 520 530 540 550
DAIFGETMVE MGAPFSLKGL MGNPICSPHY WKPSTFGGEV GFKIINTASI
560 570 580 590 600
QSLICTNVRG CPFTSFSIPD PELAKTVTIN ASASHSRLED LNPTVLLKGH

SPEL
Length:604
Mass (Da):68,992
Last modified:December 14, 2011 - v1
Checksum:i1E19FC59A714ADFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JH173553 Genomic DNA. Translation: EHB17080.1.
RefSeqiXP_004862837.1. XM_004862780.1.
XP_004907169.1. XM_004907112.1.

Genome annotation databases

GeneIDi101704771.
KEGGihgl:101704771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JH173553 Genomic DNA. Translation: EHB17080.1.
RefSeqiXP_004862837.1. XM_004862780.1.
XP_004907169.1. XM_004907112.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101704771.
KEGGihgl:101704771.

Organism-specific databases

CTDi5743.

Phylogenomic databases

InParanoidiG5C6B9.
KOiK11987.

Family and domain databases

Gene3Di1.10.640.10. 1 hit.
InterProiIPR029576. COX-2.
IPR000742. EG-like_dom.
IPR010255. Haem_peroxidase.
IPR019791. Haem_peroxidase_animal.
[Graphical view]
PANTHERiPTHR11903:SF8. PTHR11903:SF8. 1 hit.
PfamiPF03098. An_peroxidase. 1 hit.
[Graphical view]
PRINTSiPR00457. ANPEROXIDASE.
SMARTiSM00181. EGF. 1 hit.
[Graphical view]
SUPFAMiSSF48113. SSF48113. 1 hit.
PROSITEiPS50026. EGF_3. 1 hit.
PS50292. PEROXIDASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiG5C6B9_HETGA
AccessioniPrimary (citable) accession number: G5C6B9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: January 7, 2015
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.