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G5B1T1

- G5B1T1_HETGA

UniProt

G5B1T1 - G5B1T1_HETGA

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Protein
Submitted name:

Lactase-phlorizin hydrolase

Gene

GW7_18616

Organism
Heterocephalus glaber (Naked mole rat)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Names & Taxonomyi

Protein namesi
Submitted name:
Lactase-phlorizin hydrolaseImported
Gene namesi
ORF Names:GW7_18616Imported
OrganismiHeterocephalus glaber (Naked mole rat)Imported
Taxonomic identifieri10181 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaHystricognathiBathyergidaeHeterocephalus
ProteomesiUP000006813: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliG5B1T1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 1 family.UniRule annotation

Phylogenomic databases

InParanoidiG5B1T1.
KOiK01229.

Family and domain databases

Gene3Di3.20.20.80. 4 hits.
InterProiIPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10353. PTHR10353. 1 hit.
PfamiPF00232. Glyco_hydro_1. 4 hits.
[Graphical view]
PRINTSiPR00131. GLHYDRLASE1.
SUPFAMiSSF51445. SSF51445. 4 hits.
PROSITEiPS00572. GLYCOSYL_HYDROL_F1_1. 2 hits.
PS00653. GLYCOSYL_HYDROL_F1_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G5B1T1-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MEPSWKVALI ILLSFSCQGS DWESDRNFIS AAGPLTSDLL HNLSHLLGNQ
60 70 80 90 100
SSHFVAGYKD IYTCHQPLPS FIPEYFKSLH NSKITHYKVF LSWAQLLPSG
110 120 130 140 150
SSRNPDGKTL QCYRQLLEAL KTAQLQPMVI LHHQTLPTST LQRSRVFADL
160 170 180 190 200
FADYATFAFH SFGDLVGIWF TFSDLKGTMM GLSHKESRAS HLQTLTDAHR
210 220 230 240 250
KVYEIYHAKY ASQGGKLSVV LPSDDLLEAL LEPSVSALAK DSVDFLSLDL
260 270 280 290 300
SYECQSEASL PEKLNKLQSI EPKVKVFIFT LKLQDCPSTK KNPARMLFSL
310 320 330 340 350
FEAINKDHVC TIGFDVNEFL SCSSSKKSMS CSLTDSLALQ SDQQQDRDTA
360 370 380 390 400
GGPLSPDSAY WRVWEAFANQ SRTERDAFLQ DVFPEDFLWG VSTGAFNVEG
410 420 430 440 450
GWAEGGRGAS IWDQYGLNGT RGQATPEVAS DSYHKSASDV ALLRGLRAQV
460 470 480 490 500
YKFSISWSRI FPTGHRSSPN LQGVTYYNKL IDTLLGSHIK PMVTLFHWDL
510 520 530 540 550
PQALQDLGGW QNENVVDAFL DYAAFCFSTF GDRVKLWVTF HEPWVVSYAG
560 570 580 590 600
YGTGQHAPGI SDPGVASFKV AHLILKAHAR TWHHYNSHHR AQQQGSVGIV
610 620 630 640 650
LNSDWAEPLS PEQPEDLTAS ERFLHFMLGW FAHPIFVDGG YPPTMKAQIQ
660 670 680 690 700
QLNKQCSGPV AQLPEFTRAE KQLIKGSADF LGLSHYTSRL IRKGQQDTCV
710 720 730 740 750
PSYENIGGFS QHVDPAWPQT ASPWIRVVPW GIRRLLQFVS MEYTRGKVPI
760 770 780 790 800
YLAGNGMPIG ENNSLFDDSS RVAYFNQYIN EVLKAVKEDS VDVRSYIARS
810 820 830 840 850
LIDGFEGPSG YSQRFGLHHV NFSDSSKPRT PRKSACFFTT IIEKNGFTTK
860 870 880 890 900
VVKRSLPSKV AEFPSKIRTF NFPSEVPSKA KVVWEKFSNQ PKFERDFFYH
910 920 930 940 950
GTFRDDFLWG VSSSAYQIEG AWDAEGKGPS IWDNFTHTPG NAVKDNATGD
960 970 980 990 1000
IACDSYNNLD ADLNILRALK VKAYRFSMAW SRIFPDGTNS FINRAGVEYY
1010 1020 1030 1040 1050
NRLISGLVAS NILPMVTLFH WDLPQALQDI GGWENPSLIE LFDSYADFCF
1060 1070 1080 1090 1100
QTFGDRVKFW MTFNEPAIQA WNGYGLGNFP PNVKDPGWGP YRIGHAVIKA
1110 1120 1130 1140 1150
HARVYHTYDE KYRQQQQGVI SLSLSTHWAE PKSPGVPRDV EAADRMLQFS
1160 1170 1180 1190 1200
LGWFAHPIFR NGDYPDVMKW KVGNRSELQH LATSRLPSFT EEEKRYIRGT
1210 1220 1230 1240 1250
ADVFCFNTYS SRLVQHTTPP LNPPSYQYDQ EITEEEDPSW VATAINRAAP
1260 1270 1280 1290 1300
WGIRRLLNWI KEEYGDVPIY ITENGVGLTS GALQDTDRIF YHKTYINEAL
1310 1320 1330 1340 1350
KAYRLDGIDL RGYSAWSLMD NFEWLEGYTV KFGLYHVDFE DVNRPRTARA
1360 1370 1380 1390 1400
SASYYTEVIT NNGMPMPKED EFLYGEFPKG FIWSAASAAY QIEGAWRTDG
1410 1420 1430 1440 1450
KGLSIWDMYS HTPLRIENDD TGDVACDSYH KIAEDVVVLQ NLGVSHYRFS
1460 1470 1480 1490 1500
ISWTRILPDG TTKYINEMGL NYYVRLIDAL LAANIEPQVT LYHWDLPQAL
1510 1520 1530 1540 1550
QDVGGWENET IVQRFKEYAD VLFRRLGDKV KFWITLNEPF VIACHGYGTG
1560 1570 1580 1590 1600
VSAPGISSRP GTAPYTAGHN LIKAHAEAWH LYNDVYRASQ GGMISITISS
1610 1620 1630 1640 1650
DWAEPRDPSN QEDVEAARRY VQFMGGWFAH PIFKNGDYPD VMKTRIRDRS
1660 1670 1680 1690 1700
LAAGLNKSRL PEFTQSEKRR INGTYDYFGF NHYTTVLAYN LNYASVYSSF
1710 1720 1730 1740 1750
DADRGVMSIA DQSWPVSGSF WLKMTPFGFR RILNWLKEEY NNPPIYVTEN
1760 1770 1780 1790 1800
GVSQRGEVDL NDTARIYYLR SYINEALKAV QDKVDLRGYT VWTVMDNFEW
1810 1820 1830 1840 1850
ATGFTERFGL HYVNRTDPSL PRIPKESAKF YASVVRCNGF PDPAAGPHPC
1860 1870 1880 1890 1900
LQQPEDAEPT TIPVREEVPF LGLKLGITEA QTALYVLFSL MLLGVCVLAF
1910 1920
LSYKYCKFSK KEKTQPSQQE LSRISSF
Length:1,927
Mass (Da):218,273
Last modified:December 14, 2011 - v1
Checksum:i2026D7B78DC4749C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JH168039 Genomic DNA. Translation: EHB03242.1.
RefSeqiXP_004885152.1. XM_004885095.1.

Genome annotation databases

GeneIDi101697396.
KEGGihgl:101697396.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
JH168039 Genomic DNA. Translation: EHB03242.1 .
RefSeqi XP_004885152.1. XM_004885095.1.

3D structure databases

ProteinModelPortali G5B1T1.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 101697396.
KEGGi hgl:101697396.

Organism-specific databases

CTDi 3938.

Phylogenomic databases

InParanoidi G5B1T1.
KOi K01229.

Family and domain databases

Gene3Di 3.20.20.80. 4 hits.
InterProi IPR001360. Glyco_hydro_1.
IPR018120. Glyco_hydro_1_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
PANTHERi PTHR10353. PTHR10353. 1 hit.
Pfami PF00232. Glyco_hydro_1. 4 hits.
[Graphical view ]
PRINTSi PR00131. GLHYDRLASE1.
SUPFAMi SSF51445. SSF51445. 4 hits.
PROSITEi PS00572. GLYCOSYL_HYDROL_F1_1. 2 hits.
PS00653. GLYCOSYL_HYDROL_F1_2. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiG5B1T1_HETGA
AccessioniPrimary (citable) accession number: G5B1T1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: October 29, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3