G4VJ01 (G4VJ01_SCHMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative histone-lysine n-methyltransferase, setb1 EMBL CCD79402.1

Gene names

ORF Names:

Smp_150850.2 EMBL CCD79402.1

Organism

Schistosoma mansoni (Blood fluke) [Reference proteome]

Taxonomic identifier

6183 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Platyhelminthes › Trematoda › Digenea › Strigeidida › Schistosomatoidea › Schistosomatidae › Schistosoma

Protein attributes

Sequence length	1032 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine. RuleBase RU004542
Subcellular location	Nucleus By similarity RuleBase RU004542.
Sequence similarities	Contains 1 SET domain. SAAS SAAS007728 RuleBase RU004538 Contains 1 pre-SET domain. SAAS SAAS007728 RuleBase RU004542

Ontologies

Keywords
Cellular component	Chromosome SAAS SAAS007728 Nucleus SAAS SAAS007728 RuleBase RU004542
Molecular function	Methyltransferase SAAS SAAS007728 RuleBase RU004542 EMBL CCD79402.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	chromosome Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G4VJ01 [UniParc]. Last modified December 14, 2011. Version 1. Checksum: 5E28402369A697ED	FASTA	1,032	118,377
	10 20 30 40 50 60 MNVLKHEHRV LIDELTESIY DALDSDDIFD VIFAFVESKY QAELKDVNNP KLRLHIIQQR 70 80 90 100 110 120 FSLALEECGL IDEIIESFPE LNLNARLDKL KKEQSTLQSN ILELNGKIDT IVDEMTRLQI 130 140 150 160 170 180 NSFGRVLRLF DNRVIDLAKD EEEIVVIERP NNRIPESTIN HSTAPVWRTL QPAELLLGLQ 190 200 210 220 230 240 LTPSQPVLYR KTQHTWFPGR VLSCHLPNSD PSTPKSDKDR AKENENAQYT IALDTSSKSK 250 260 270 280 290 300 SEICFAVTSS LALAFSASEL RQKYPVGARV VSIYRDDTGG IGYYSGLIAE PPSERNNQRY 310 320 330 340 350 360 LLFFDDGYTQ YSPPNEVYRI CHQSKENWKE ATESSQEFIK RYLAQYPQRP MVRLKPGQTV 370 380 390 400 410 420 ETELDGDWMK ATVEKVDASL ALMKFSRTHS EWIYRGSTRL EPLFSDLLSS QSKSVPTHNQ 430 440 450 460 470 480 RVEVEYSSVD VPLDSSAKRR KARKSATGNQ NTAMSVRALS SGDSHKISNS IHQTNKSLSN 490 500 510 520 530 540 YNNEALKTTS KKGSEKNINE QCLSIDPITN LSELESTGTK TSYLDNLFKE FDYKPFESHK 550 560 570 580 590 600 CGHYCLKSYR KPSSALSPIL CSENPVDYKG LNPLEIPFHC GWLRYLAKYD PPVNNKCNII 610 620 630 640 650 660 YTAPCGRSLR SMHEVERFLD KTNSQLTADL FSFDSTLIIN QEFRAEKTLT NIVDLSYGKE 670 680 690 700 710 720 NVPIPCVNSV DNEVPGYIDY TPQRQPIGNV PLLKDSKFLV CCDCTDNCRD RTKCACQQLT 730 740 750 760 770 780 VEASSLTNPN GLVDSQAGYR YRRLSQFTVG GVYECNSNCQ CDRRCSNRVV QQGLWVRLQV 790 800 810 820 830 840 FKTARKGWGI RALNAIPKGT FICTYAGAIY DEAMAVQEGF DCGDEYQAEL DYIETVEKDK 850 860 870 880 890 900 EGYESTVEDL NEILNETTVA LIQRSASLEP EIKDRKPLER SKSHRKDSEK QHRRQHHHHH 910 920 930 940 950 960 HHHRNHRQQQ LQQLSQSHQQ NQQQTKRMYP VAQKDWLRAR TYFNDINPYI MDAKKMGNLG 970 980 990 1000 1010 1020 RYFNHSCNPN VFVQNVFIDT HDPRFPEVAF FAKRNIDVGE EMTWDYGYTV DAVPFKVLYC 1030 YCGEPNCRIR LL

References

[1]

"A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni." Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A., De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C., Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J., Oliveira G., Otto T.D. , Parker-Manuel S.J., Quail M.A., Wilson R.A., Zerlotini A., Dunne D.W., Berriman M. PLoS Negl. Trop. Dis. 6:E1455-E1455(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Puerto Rican.

Cross-references

Sequence databases
EMBL GenBank DDBJ	HE601627 Genomic DNA. Translation: CCD79402.1.
RefSeq	XP_002576654.1. XM_002576608.1.
UniGene	Sma.10940.
3D structure databases
ProteinModelPortal	G4VJ01.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8344287.
KEGG	smm:Smp_150850.2.
Organism-specific databases
CTD	8344287.
Phylogenomic databases
KO	K11421.
OMA	QCWQLTI.
PhylomeDB	G4VJ01.
Family and domain databases
Gene3D	3.30.890.10. 1 hit.
InterPro	IPR016177. DNA-bd_integrase-typ. IPR001739. Methyl_CpG_DNA-bd. IPR007728. Pre-SET_dom. IPR001214. SET_dom. [Graphical view]
Pfam	PF01429. MBD. 1 hit. PF05033. Pre-SET. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF54171. DNA-binding_integrase-type. 1 hit.
PROSITE	PS50982. MBD. 1 hit. PS50867. PRE_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G4VJ01_SCHMA

Accession

Primary (citable) accession number: G4VJ01

Entry history

Integrated into UniProtKB/TrEMBL:	December 14, 2011
Last sequence update:	December 14, 2011
Last modified:	March 6, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)