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G4VFD7

- G4VFD7_SCHMA

UniProt

G4VFD7 - G4VFD7_SCHMA

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Protein
Submitted name:

Dihydroorotate dehydrogenase

Gene

Smp_078730

Organism
Schistosoma mansoni (Blood fluke)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei203 – 2031NucleophileUniRule annotation

GO - Molecular functioni

  1. dihydroorotate dehydrogenase activity Source: InterPro

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  2. UMP biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Dihydroorotate dehydrogenaseImported (EC:1.3.98.1Imported)
Gene namesi
ORF Names:Smp_078730Imported
OrganismiSchistosoma mansoni (Blood fluke)Imported
Taxonomic identifieri6183 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
ProteomesiUP000008854: Chromosome 3

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliG4VFD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

InParanoidiG4VFD7.
OMAiGECIDAF.
PhylomeDBiG4VFD7.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR012135. Dihydroorotate_DH_1_2.
IPR005719. Dihydroorotate_DH_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view]
PfamiPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFiPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsiTIGR01036. pyrD_sub2. 1 hit.
PROSITEiPS00911. DHODEHASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G4VFD7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRIRTSLEV LSLGFGLFTA EALYSGNEHF YKDWFLPTAR LLVRDGETAH
60 70 80 90 100
NLSVYLASYG FIPHKQRNSF PQLKCKVFGL EFDHPIGLAA GFDKDGKAFM
110 120 130 140 150
GLLNAGFSHI EVGTVTPNPQ LGNARPRIFR WTEKEAVVNR CGFNSDGHDA
160 170 180 190 200
VYERLKDRPW EGRGVIGVNL GCNKTSADPT ADYVAGVRKF GEVADYLVIN
210 220 230 240 250
VSSPNTPGLR SLQTKEKLRD LLSKVLAARN QLSKKTPILL KISPDENDQN
260 270 280 290 300
LKDIVEVALD SKTRIDGMII SNTTLTTYEE AVACGAAPIP GNNKQNVVYG
310 320 330 340 350
GLSGRPLFEK STDCLRKVSA LTKGAIPLIG VGGISCGEDA LSKLNAGASL
360 370
VQLYTSFVYQ GPPVAHKVAR EINKLKMTS
Length:379
Mass (Da):41,289
Last modified:December 14, 2011 - v1
Checksum:iECFD1BFB9BD01E4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601626 Genomic DNA. Translation: CCD78646.1.

Genome annotation databases

EnsemblMetazoaiSmp_078730.1; Smp_078730.1:pep; Smp_078730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HE601626 Genomic DNA. Translation: CCD78646.1 .

3D structure databases

ProteinModelPortali G4VFD7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Smp_078730.1 ; Smp_078730.1:pep ; Smp_078730 .

Phylogenomic databases

InParanoidi G4VFD7.
OMAi GECIDAF.
PhylomeDBi G4VFD7.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR012135. Dihydroorotate_DH_1_2.
IPR005719. Dihydroorotate_DH_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view ]
Pfami PF01180. DHO_dh. 1 hit.
[Graphical view ]
PIRSFi PIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsi TIGR01036. pyrD_sub2. 1 hit.
PROSITEi PS00911. DHODEHASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Puerto RicanImported.

Entry informationi

Entry nameiG4VFD7_SCHMA
AccessioniPrimary (citable) accession number: G4VFD7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: November 26, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3