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G4VEG6

- G4VEG6_SCHMA

UniProt

G4VEG6 - G4VEG6_SCHMA

Protein

Mitogen-activated protein kinase

Gene

Smp_140700

Organism
Schistosoma mansoni (Blood fluke)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotation

    Enzyme regulationi

    Activated by threonine and tyrosine phosphorylation.UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. MAP kinase activity Source: InterPro

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mitogen-activated protein kinaseUniRule annotation (EC:2.7.11.24UniRule annotation)
    Gene namesi
    ORF Names:Smp_140700Imported
    OrganismiSchistosoma mansoni (Blood fluke)Imported
    Taxonomic identifieri6183 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
    ProteomesiUP000008854: Chromosome 2

    Structurei

    3D structure databases

    ProteinModelPortaliG4VEG6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.UniRule annotation
    Contains 1 protein kinase domain.UniRule annotation
    Contains protein kinase domain.SAAS annotation

    Phylogenomic databases

    KOiK04468.
    OMAiHRSHANI.
    PhylomeDBiG4VEG6.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G4VEG6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLVPINFPYS AETYQKQFLN PSTPLPGSLS VFPNVLHYSE KVAAMFNGLQ    50
    IGPSLRCANL IPQKGPQHII GGPVLAVVKS TFSPVGYGNS QRLENGFTFQ 100
    PSLTQKVYMP EKSLGFGAFG VVWLVVDPRT GDQVALKRIP NIFESIVSAK 150
    RAYRELKLLF SLRHSNIVRL IDVVKVSSSS LFSEVSVLCE YMDTDLHKII 200
    VSTQYLSLEH VKLFVYQILR GLKYLHSAGV IHRDLKPGNL LVNSDCLLKI 250
    CDFGLARSVP SFDVESPSNP LTLEVVTQFY RPPELLLGSN FYTAAVDQWS 300
    VGCILGELLC RQILFQSSSS FRQLDMIFNL LGSPNAMELI DLVGFPSSSI 350
    DFIRNCPVRP FNHAAVSRIL VPANTQYFQS STENPPDPDL VNLFTGLLSF 400
    SSSKRLTAEQ ALDSPFLIGG RARFHTCLCS CCPPRNQNSI INDSSSHWRN 450
    VTNQVNRHHL VAVGSVGTLS SSGGTPPSSL HSSMLSQSRD ITLRIPLFLS 500
    PHLMVPTSLI RYRRINLEPT FQDIHEYTYI NTEIQMNNLF EAKQILWNLI 550
    QQYFQRDPNR TRVVINNSSP NFQSFIK 577
    Length:577
    Mass (Da):64,576
    Last modified:December 14, 2011 - v1
    Checksum:iCE5D690895F93156
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE601625 Genomic DNA. Translation: CCD77182.1.
    UniGeneiSma.4729.

    Genome annotation databases

    EnsemblMetazoaiSmp_140700.1; Smp_140700.1:pep; Smp_140700.
    KEGGismm:Smp_140700.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE601625 Genomic DNA. Translation: CCD77182.1 .
    UniGenei Sma.4729.

    3D structure databases

    ProteinModelPortali G4VEG6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai Smp_140700.1 ; Smp_140700.1:pep ; Smp_140700 .
    KEGGi smm:Smp_140700.

    Phylogenomic databases

    KOi K04468.
    OMAi HRSHANI.
    PhylomeDBi G4VEG6.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Puerto RicanImported.

    Entry informationi

    Entry nameiG4VEG6_SCHMA
    AccessioniPrimary (citable) accession number: G4VEG6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3