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G4V907

- G4V907_SCHMA

UniProt

G4V907 - G4V907_SCHMA

Protein

DNA ligase

Gene

Smp_148660

Organism
Schistosoma mansoni (Blood fluke)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:Smp_148660Imported
    OrganismiSchistosoma mansoni (Blood fluke)Imported
    Taxonomic identifieri6183 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
    ProteomesiUP000008854: Chromosome 1

    Structurei

    3D structure databases

    ProteinModelPortaliG4V907.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK10777.
    OMAiISHFLCA.
    PhylomeDBiG4V907.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SMARTiSM00292. BRCT. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G4V907-1 [UniParc]FASTAAdd to Basket

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    MDVIFESSRI AKNVSFTTYC RLLEKLASSD GVKTKEKILS RFVILWETQY    50
    LALDSISQYP CGGRASLYLL LRLLIPSHDR SRKAFGLRGQ TLSRLIIKAI 100
    GLAPNSLAAR KLSHIHPNSI HRQTDFADVA YTVLRARCRE DSVLSVKDLN 150
    THLDELSTAE SYDMRLQVLR SLLQLTTALE QKWIIRLIVK RDSGCGLSGK 200
    SILRCFHPAA VSVFEVTQDL LPLCERIANI PSPNTFMLTG YANNLSKSFD 250
    VTLFVPFRPM LCERANSGDM LVNSALHLYG KQNQGDTKGL KLLFETKFDG 300
    ERVQLHKSSN SYRYWSRNGL EWTASYGEDG TRDFDRLSAQ LHCGFAQHVT 350
    DCILDGEMMI FSKWSNSIMS KSTKFDVKRS SYQNPEIDNY QPCFIVFDIL 400
    YLNSQVCLSY PYHINDFKPI PIINGIMYVS KWYTASAHQT EVARAFNHLV 450
    DNHQEGLIVK IANSPSLYLP GIRTDGGWWK IKPDYIQGLL EDLDCLIVGG 500
    YFHHRGDKII TRVNHFLCAV RNDESYESTS EDNFTLTRFY TFCKVKSGLT 550
    VKQLKEINQL LGKHWKVYDK KHPNSSSTEW LCVNSERPDV WIAPRSSLVL 600
    QLHGAELIQS DSYSCGITLR FPRVVAIRHD KNWRDSLSMS ELIKLNTETE 650
    GKLATKRLSI VPTFSGLADV EHQQSFPDIS SLNSSCSSTN QSSGYHTLNE 700
    TTEQQTTELF INVDEPLATS SPIKQRKIDV CHEHLNYFEN HEICLWLSND 750
    IELNKKLELE AIIRRYGGVV VQNPSESTFC IVADKLTLKL STSQETEFNI 800
    WLNKNYSILN TWIRQFPRIP HFIKESWLTE CIMQSSWCSE LNHLIEIN 848
    Length:848
    Mass (Da):96,966
    Last modified:December 14, 2011 - v1
    Checksum:i48EA2647122EA354
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE601624 Genomic DNA. Translation: CCD76233.1.

    Genome annotation databases

    EnsemblMetazoaiSmp_148660.1; Smp_148660.1:pep; Smp_148660.
    KEGGismm:Smp_148660.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    HE601624 Genomic DNA. Translation: CCD76233.1 .

    3D structure databases

    ProteinModelPortali G4V907.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai Smp_148660.1 ; Smp_148660.1:pep ; Smp_148660 .
    KEGGi smm:Smp_148660.

    Phylogenomic databases

    KOi K10777.
    OMAi ISHFLCA.
    PhylomeDBi G4V907.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SMARTi SM00292. BRCT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 1 hit.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Puerto RicanImported.

    Entry informationi

    Entry nameiG4V907_SCHMA
    AccessioniPrimary (citable) accession number: G4V907
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3