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G4V907

- G4V907_SCHMA

UniProt

G4V907 - G4V907_SCHMA

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Protein
DNA ligase
Gene
Smp_148660
Organism
Schistosoma mansoni (Blood fluke)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:Smp_148660Imported
OrganismiSchistosoma mansoni (Blood fluke)
Taxonomic identifieri6183 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
ProteomesiUP000008854: Chromosome 1

Structurei

3D structure databases

ProteinModelPortaliG4V907.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK10777.
OMAiISHFLCA.
PhylomeDBiG4V907.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G4V907-1 [UniParc]FASTAAdd to Basket

« Hide

MDVIFESSRI AKNVSFTTYC RLLEKLASSD GVKTKEKILS RFVILWETQY    50
LALDSISQYP CGGRASLYLL LRLLIPSHDR SRKAFGLRGQ TLSRLIIKAI 100
GLAPNSLAAR KLSHIHPNSI HRQTDFADVA YTVLRARCRE DSVLSVKDLN 150
THLDELSTAE SYDMRLQVLR SLLQLTTALE QKWIIRLIVK RDSGCGLSGK 200
SILRCFHPAA VSVFEVTQDL LPLCERIANI PSPNTFMLTG YANNLSKSFD 250
VTLFVPFRPM LCERANSGDM LVNSALHLYG KQNQGDTKGL KLLFETKFDG 300
ERVQLHKSSN SYRYWSRNGL EWTASYGEDG TRDFDRLSAQ LHCGFAQHVT 350
DCILDGEMMI FSKWSNSIMS KSTKFDVKRS SYQNPEIDNY QPCFIVFDIL 400
YLNSQVCLSY PYHINDFKPI PIINGIMYVS KWYTASAHQT EVARAFNHLV 450
DNHQEGLIVK IANSPSLYLP GIRTDGGWWK IKPDYIQGLL EDLDCLIVGG 500
YFHHRGDKII TRVNHFLCAV RNDESYESTS EDNFTLTRFY TFCKVKSGLT 550
VKQLKEINQL LGKHWKVYDK KHPNSSSTEW LCVNSERPDV WIAPRSSLVL 600
QLHGAELIQS DSYSCGITLR FPRVVAIRHD KNWRDSLSMS ELIKLNTETE 650
GKLATKRLSI VPTFSGLADV EHQQSFPDIS SLNSSCSSTN QSSGYHTLNE 700
TTEQQTTELF INVDEPLATS SPIKQRKIDV CHEHLNYFEN HEICLWLSND 750
IELNKKLELE AIIRRYGGVV VQNPSESTFC IVADKLTLKL STSQETEFNI 800
WLNKNYSILN TWIRQFPRIP HFIKESWLTE CIMQSSWCSE LNHLIEIN 848
Length:848
Mass (Da):96,966
Last modified:December 14, 2011 - v1
Checksum:i48EA2647122EA354
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE601624 Genomic DNA. Translation: CCD76233.1.

Genome annotation databases

EnsemblMetazoaiSmp_148660.1; Smp_148660.1:pep; Smp_148660.
KEGGismm:Smp_148660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE601624 Genomic DNA. Translation: CCD76233.1 .

3D structure databases

ProteinModelPortali G4V907.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Smp_148660.1 ; Smp_148660.1:pep ; Smp_148660 .
KEGGi smm:Smp_148660.

Phylogenomic databases

KOi K10777.
OMAi ISHFLCA.
PhylomeDBi G4V907.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 1 hit.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Puerto Rican.

Entry informationi

Entry nameiG4V907_SCHMA
AccessioniPrimary (citable) accession number: G4V907
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: September 3, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3