G4V7G8 (G4V7G8_SCHMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative adenosine kinase EMBL CCD75963.1
EC=2.7.1.20 EMBL CCD75963.1

Gene names

ORF Names:

Smp_008360 EMBL CCD75963.1

Organism

Schistosoma mansoni (Blood fluke) [Reference proteome]

Taxonomic identifier

6183 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Platyhelminthes › Trematoda › Digenea › Strigeidida › Schistosomatoidea › Schistosomatidae › Schistosoma

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Kinase EMBL CCD75963.1 Transferase
Technical term	3D-structure PDB 3UQ6 PDB 4DC3 PDB 3UQ9 PDB 3VAQ PDB 3VAS Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	AMP biosynthetic process Inferred from electronic annotation. Source: GOC purine ribonucleoside salvage Inferred from electronic annotation. Source: InterPro
Molecular_function	adenosine kinase activity Inferred from electronic annotation. Source: EC phosphotransferase activity, alcohol group as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G4V7G8 [UniParc]. Last modified December 14, 2011. Version 1. Checksum: 68B7BD774E7BBAD5	FASTA	352	39,392
	10 20 30 40 50 60 MHDLSEGYVF GMGNPLLDII VDADDFMYRK YNLKKDNIVL AEEKHMTIYD EIQKKKKLNY 70 80 90 100 110 120 IAGGATLNTV KMIQWIIQKP FVCSYVGCIG ADIQGKYIKN DCSALDLVTE FQIAEEPLMT 130 140 150 160 170 180 GKVAVLVSEK LRSMVTYLGA ACDLSLAHIE QPHVWSLVEK AQVYYIAGFV INTCYEGMLK 190 200 210 220 230 240 IAKHSLENEK LFCFNLSAPF LSQFNTKEVD EMISYSNIVF GNESEAEAYG EVHGLLEDTV 250 260 270 280 290 300 HATARYIADL PFADGKKRKR LVIITRGKNP LLYTDSSDSE IHQFMVEQFK DDQIIDTNGA 310 320 330 340 350 GDAFAAGFIA DYIRGKPMIT SLHAAVKAAA YIICRSGFSL GSRDSYSLKI NK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni." Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A., De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C., Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J., Oliveira G., Otto T.D. , Parker-Manuel S.J., Quail M.A., Wilson R.A., Zerlotini A., Dunne D.W., Berriman M. PLoS Negl. Trop. Dis. 6:E1455-E1455(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Puerto Rican.
[2]	"Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues." Romanello L., Bachega J.F., Cassago A., Brandao-Neto J., DeMarco R., Garratt R.C., Pereira H.D. Acta Crystallogr. D 69:126-136(2013) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.26 ANGSTROMS) OF 2-352.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

HE601624 Genomic DNA. Translation: CCD75963.1.

RefSeq

XP_002572312.1. XM_002572266.1.

UniGene

Sma.8196.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3UQ6	X-ray	2.30	A/B	1-352	[»]
3UQ9	X-ray	2.34	A/B	1-352	[»]
3VAQ	X-ray	2.44	A/B	3-352	[»]
3VAS	X-ray	2.26	A/B	2-352	[»]
4DC3	X-ray	2.40	A/B	3-352	[»]

ProteinModelPortal

G4V7G8.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

8350698.

KEGG

smm:Smp_008360.

Organism-specific databases

CTD

8350698.

Phylogenomic databases

KO

K00856.

OMA

FFKDNLM.

PhylomeDB

G4V7G8.

Family and domain databases

InterPro

IPR001805. Adenokinase.
IPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
[Graphical view]

PANTHER

PTHR10584:SF24. PTHR10584:SF24. 1 hit.

Pfam

PF00294. PfkB. 1 hit.
[Graphical view]

PRINTS

PR00989. ADENOKINASE.

PROSITE

PS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

G4V7G8_SCHMA

Accession

Primary (citable) accession number: G4V7G8

Entry history

Integrated into UniProtKB/TrEMBL:	December 14, 2011
Last sequence update:	December 14, 2011
Last modified:	May 1, 2013
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)