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G4V7G8 (G4V7G8_SCHMA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=2.7.1.20 EMBL CCD75963.1
Gene names
ORF Names:Smp_008360 EMBL CCD75963.1
OrganismSchistosoma mansoni (Blood fluke) [Reference proteome]
Taxonomic identifier6183 [NCBI]
Taxonomic lineageEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding265 – 2673AMP

Sites

Binding site141Chloride; via amide nitrogen PDB 3UQ6 PDB 4DC3 PDB 3UQ9 PDB 3VAQ PDB 3VAS
Binding site661Chloride PDB 3UQ6 PDB 4DC3 PDB 3UQ9 PDB 3VAQ PDB 3VAS

Sequences

Sequence LengthMass (Da)Tools
G4V7G8 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 68B7BD774E7BBAD5

FASTA35239,392
        10         20         30         40         50         60 
MHDLSEGYVF GMGNPLLDII VDADDFMYRK YNLKKDNIVL AEEKHMTIYD EIQKKKKLNY 

        70         80         90        100        110        120 
IAGGATLNTV KMIQWIIQKP FVCSYVGCIG ADIQGKYIKN DCSALDLVTE FQIAEEPLMT 

       130        140        150        160        170        180 
GKVAVLVSEK LRSMVTYLGA ACDLSLAHIE QPHVWSLVEK AQVYYIAGFV INTCYEGMLK 

       190        200        210        220        230        240 
IAKHSLENEK LFCFNLSAPF LSQFNTKEVD EMISYSNIVF GNESEAEAYG EVHGLLEDTV 

       250        260        270        280        290        300 
HATARYIADL PFADGKKRKR LVIITRGKNP LLYTDSSDSE IHQFMVEQFK DDQIIDTNGA 

       310        320        330        340        350 
GDAFAAGFIA DYIRGKPMIT SLHAAVKAAA YIICRSGFSL GSRDSYSLKI NK 

« Hide

References

« Hide 'large scale' references
[1]"A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni."
Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A., De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C., Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J., Oliveira G., Otto T.D. expand/collapse author list , Parker-Manuel S.J., Quail M.A., Wilson R.A., Zerlotini A., Dunne D.W., Berriman M.
PLoS Negl. Trop. Dis. 6:E1455-E1455(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Puerto Rican.
[2]"Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues."
Romanello L., Bachega J.F., Cassago A., Brandao-Neto J., DeMarco R., Garratt R.C., Pereira H.D.
Acta Crystallogr. D 69:126-136(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.26 ANGSTROMS) OF 2-352 IN COMPLEX WITH AMP AND CHLORIDE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
HE601624 Genomic DNA. Translation: CCD75963.1.
UniGeneSma.8196.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3UQ6X-ray2.30A/B1-352[»]
3UQ9X-ray2.34A/B1-352[»]
3VAQX-ray2.44A/B1-352[»]
3VASX-ray2.26A/B2-352[»]
4DC3X-ray2.40A/B1-352[»]
ProteinModelPortalG4V7G8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaSmp_008360.1; Smp_008360.1:pep; Smp_008360.
KEGGsmm:Smp_008360.

Organism-specific databases

CTD8350698.

Phylogenomic databases

KOK00856.
OMACIANIEK.
PhylomeDBG4V7G8.

Family and domain databases

Gene3D3.40.1190.20. 1 hit.
InterProIPR001805. Adenokinase.
IPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
[Graphical view]
PANTHERPTHR10584:SF24. PTHR10584:SF24. 1 hit.
PfamPF00294. PfkB. 1 hit.
[Graphical view]
PRINTSPR00989. ADENOKINASE.
SUPFAMSSF53613. SSF53613. 1 hit.
PROSITEPS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4V7G8_SCHMA
AccessionPrimary (citable) accession number: G4V7G8
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: July 9, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)