SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G4V7G8

- G4V7G8_SCHMA

UniProt

G4V7G8 - G4V7G8_SCHMA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Putative adenosine kinase
Gene
Smp_008360
Organism
Schistosoma mansoni (Blood fluke)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi265 – 2673AMPImported

GO - Molecular functioni

  1. adenosine kinase activity Source: UniProtKB-EC
  2. nucleotide binding Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro

GO - Biological processi

  1. purine ribonucleoside salvage Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Keywords - Ligandi

Nucleotide-bindingImported

Names & Taxonomyi

Protein namesi
Submitted name:
Putative adenosine kinaseImported (EC:2.7.1.20Imported)
Gene namesi
ORF Names:Smp_008360Imported
OrganismiSchistosoma mansoni (Blood fluke)
Taxonomic identifieri6183 [NCBI]
Taxonomic lineageiEukaryotaMetazoaPlatyhelminthesTrematodaDigeneaStrigeididaSchistosomatoideaSchistosomatidaeSchistosoma
ProteomesiUP000008854: Chromosome 1

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3UQ6X-ray2.30A/B1-352[»]
3UQ9X-ray2.34A/B1-352[»]
3VAQX-ray2.44A/B1-352[»]
3VASX-ray2.26A/B2-352[»]
4DC3X-ray2.40A/B1-352[»]
ProteinModelPortaliG4V7G8.

Family & Domainsi

Phylogenomic databases

KOiK00856.
OMAiCIANIEK.
PhylomeDBiG4V7G8.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
InterProiIPR001805. Adenokinase.
IPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
[Graphical view]
PANTHERiPTHR10584:SF24. PTHR10584:SF24. 1 hit.
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
PRINTSiPR00989. ADENOKINASE.
SUPFAMiSSF53613. SSF53613. 1 hit.
PROSITEiPS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G4V7G8-1 [UniParc]FASTAAdd to Basket

« Hide

MHDLSEGYVF GMGNPLLDII VDADDFMYRK YNLKKDNIVL AEEKHMTIYD    50
EIQKKKKLNY IAGGATLNTV KMIQWIIQKP FVCSYVGCIG ADIQGKYIKN 100
DCSALDLVTE FQIAEEPLMT GKVAVLVSEK LRSMVTYLGA ACDLSLAHIE 150
QPHVWSLVEK AQVYYIAGFV INTCYEGMLK IAKHSLENEK LFCFNLSAPF 200
LSQFNTKEVD EMISYSNIVF GNESEAEAYG EVHGLLEDTV HATARYIADL 250
PFADGKKRKR LVIITRGKNP LLYTDSSDSE IHQFMVEQFK DDQIIDTNGA 300
GDAFAAGFIA DYIRGKPMIT SLHAAVKAAA YIICRSGFSL GSRDSYSLKI 350
NK 352
Length:352
Mass (Da):39,392
Last modified:December 14, 2011 - v1
Checksum:i68B7BD774E7BBAD5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE601624 Genomic DNA. Translation: CCD75963.1.
UniGeneiSma.8196.

Genome annotation databases

EnsemblMetazoaiSmp_008360.1; Smp_008360.1:pep; Smp_008360.
KEGGismm:Smp_008360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
HE601624 Genomic DNA. Translation: CCD75963.1 .
UniGenei Sma.8196.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3UQ6 X-ray 2.30 A/B 1-352 [» ]
3UQ9 X-ray 2.34 A/B 1-352 [» ]
3VAQ X-ray 2.44 A/B 1-352 [» ]
3VAS X-ray 2.26 A/B 2-352 [» ]
4DC3 X-ray 2.40 A/B 1-352 [» ]
ProteinModelPortali G4V7G8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Smp_008360.1 ; Smp_008360.1:pep ; Smp_008360 .
KEGGi smm:Smp_008360.

Phylogenomic databases

KOi K00856.
OMAi CIANIEK.
PhylomeDBi G4V7G8.

Family and domain databases

Gene3Di 3.40.1190.20. 1 hit.
InterProi IPR001805. Adenokinase.
IPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
[Graphical view ]
PANTHERi PTHR10584:SF24. PTHR10584:SF24. 1 hit.
Pfami PF00294. PfkB. 1 hit.
[Graphical view ]
PRINTSi PR00989. ADENOKINASE.
SUPFAMi SSF53613. SSF53613. 1 hit.
PROSITEi PS00584. PFKB_KINASES_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Puerto Rican.
  2. "Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues."
    Romanello L., Bachega J.F., Cassago A., Brandao-Neto J., DeMarco R., Garratt R.C., Pereira H.D.
    Acta Crystallogr. D 69:126-136(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.26 ANGSTROMS) OF 2-352 IN COMPLEX WITH AMP.

Entry informationi

Entry nameiG4V7G8_SCHMA
AccessioniPrimary (citable) accession number: G4V7G8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: September 3, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi