G4RM28 (G4RM28_THETK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aspartate-semialdehyde dehydrogenase EMBL CCC82623.1
EC=1.2.1.11 EMBL CCC82623.1

Gene names

Name:	asd EMBL CCC82623.1
Ordered Locus Names:	TTX_2009 EMBL CCC82623.1

Organism

Thermoproteus tenax (strain ATCC 35583 / NBRC 100435 / JCM 9277 / Kra 1) [Complete proteome] [HAMAP] EMBL CCC82623.1

Taxonomic identifier

768679 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Thermoproteus › Thermoproteus tenax

Protein attributes

Sequence length	354 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aspartate-semialdehyde dehydrogenase family. RuleBase RU004041

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CCC82623.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	aspartate metabolic process Inferred from electronic annotation. Source: InterPro isoleucine biosynthetic process Inferred from electronic annotation. Source: InterPro lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: InterPro methionine biosynthetic process Inferred from electronic annotation. Source: InterPro threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	N-acetyl-gamma-glutamyl-phosphate reductase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro NADP binding Inferred from electronic annotation. Source: InterPro aspartate-semialdehyde dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	163	1	Acyl-thioester intermediate By similarity PIRSR PIRSR000148-1
	Active site	247	1	Proton acceptor By similarity PIRSR PIRSR000148-1

Sequences

	Sequence		Length	Mass (Da)
	G4RM28 [UniParc]. Last modified December 14, 2011. Version 1. Checksum: D848FCB94F25D3A6	FASTA	354	39,010
	10 20 30 40 50 60 MGPRPLRQAL LREARMDKLR AYVIGATGLV GQRYVQLLAE HPWFELVGVA ASERSAGKRY 70 80 90 100 110 120 GDINWVLETP LPEKAAELKI DKLDVDSVPK VDVVFSALPS EVAAKVEPEL ARRGYLVVSN 130 140 150 160 170 180 SSNMRLEPDI PLVIPEVNPR DLELLREQRK RGWSGGIIKK PNCSTTILDL PLKPILDEFG 190 200 210 220 230 240 IVRLHVVTMQ AVSGAGFSGV ASMAILDNLI PYIRGEEEKI VNETKKIFRR DLEIYATTTR 250 260 270 280 290 300 VPVVDGHTEV VYVDTERDFD IEGVLELLAK FRGLPQELGL PTAPEAPIIV TKNPDRPQPR 310 320 330 340 350 LDRMAGNGMS VVVGRARKLG ARKLAFVVLG HNTIRGAAGN AVLATELLIK LGLY

References

[1]

"The Complete Genome Sequence of Thermoproteus tenax: A Physiologically Versatile Member of the Crenarchaeota." Siebers B., Zaparty M., Raddatz G., Tjaden B., Albers S.V., Bell S.D., Blombach F., Kletzin A., Kyrpides N., Lanz C., Plagens A., Rampp M., Rosinus A., von Jan M., Makarova K.S., Klenk H.P., Schuster S.C., Hensel R. PLoS ONE 6:e24222-e24222(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35583 / NBRC 100435 / JCM 9277 / Kra 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN869859 Genomic DNA. Translation: CCC82623.1.
RefSeq	YP_004893701.1. NC_016070.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CCC82623; CCC82623; TTX_2009.
GeneID	11262898.
KEGG	ttn:TTX_2009.
Organism-specific databases
CMR	Search...
Phylogenomic databases
KO	K00133.
Enzyme and pathway databases
BioCyc	TTEN768679:GJSY-1994-MONOMER.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR005676. Asp_semi-ald_DH_pep-lack. IPR012080. Asp_semialdehyde_DH. IPR016040. NAD(P)-bd_dom. IPR000534. Semialdehyde_DH_NAD-bd. IPR012280. Semialdhyde_DH_dimer_dom. [Graphical view]
Pfam	PF01118. Semialdhyde_dh. 1 hit. PF02774. Semialdhyde_dhC. 1 hit. [Graphical view]
PIRSF	PIRSF000148. ASA_dh. 1 hit.
SMART	SM00859. Semialdhyde_dh. 1 hit. [Graphical view]
TIGRFAMs	TIGR00978. asd_EA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G4RM28_THETK

Accession

Primary (citable) accession number: G4RM28

Entry history

Integrated into UniProtKB/TrEMBL:	December 14, 2011
Last sequence update:	December 14, 2011
Last modified:	May 29, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)