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G4RKR5

- G4RKR5_THETK

UniProt

G4RKR5 - G4RKR5_THETK

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Protein
Glyceraldehyde-3-phosphate dehydrogenase
Gene
gap, TTX_1534
Organism
Thermoproteus tenax (strain ATCC 35583 / NBRC 100435 / JCM 9277 / Kra 1)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei108 – 1081NAD; via amide nitrogen By similarityUniRule annotation
Active sitei138 – 1381Nucleophile By similarityUniRule annotation
Binding sitei167 – 1671NAD By similarityUniRule annotation
Binding sitei300 – 3001NAD; via carbonyl oxygen By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 112NAD By similarityUniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. NADP binding Source: InterPro
  3. glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity Source: UniProtKB-EC
  4. glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

NADUniRule annotationSAAS annotations, NADPUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciTTEN768679:GJSY-1508-MONOMER.
UniPathwayiUPA00109; UER00184.

Names & Taxonomyi

Protein namesi
Recommended name:
Glyceraldehyde-3-phosphate dehydrogenaseUniRule annotation (EC:1.2.1.59UniRule annotation)
Short name:
GAPDHUniRule annotation
Alternative name(s):
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase
Gene namesi
Name:gapUniRule annotationImported
Ordered Locus Names:TTX_1534Imported
OrganismiThermoproteus tenax (strain ATCC 35583 / NBRC 100435 / JCM 9277 / Kra 1)Imported
Taxonomic identifieri768679 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaeThermoproteus
ProteomesiUP000002654: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni137 – 1393Glyceraldehyde 3-phosphate binding By similarityUniRule annotation
Regioni193 – 1942Glyceraldehyde 3-phosphate binding By similarityUniRule annotation

Sequence similaritiesi

Phylogenomic databases

KOiK00150.
OMAiVTVPSHH.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00559. G3P_dehdrog_arch.
InterProiIPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000149. GAP_DH. 1 hit.
SMARTiSM00846. Gp_dh_N. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01546. GAPDH-II_archae. 1 hit.
PROSITEiPS00071. GAPDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G4RKR5-1 [UniParc]FASTAAdd to Basket

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MKVAIVGYGT IGKRVADAVS RQDDMTLVGI YKVTPDYEAV AAAQKGYRVF    50
APREKADAFK KIGVEVEGDL NDLASRADVI VDATPDGVGA QNKELYVKLG 100
KNAIFQGGEE ADVAEVSFNA LGNYEKALGK RYIRVVSCNT TSITRVLSSL 150
LLNGYKIRRA RVFITRRGAD PKEHKKGPIN DVVPNPATVP SHHGPDVQTV 200
LEGIDIVTLA VAVPVTIMHM HMAYIELDEA PSKDAVMEAL ATTPRILLFE 250
TKKGYSSLAQ IIEWARDIGR PRGDVWEVSV LQDSVTVRGN ELYLMYGVHQ 300
EAVVVPENID AIRAMYRLAD KWSSIEKTDK SLGIVTHGKK YNR 343
Length:343
Mass (Da):37,680
Last modified:December 14, 2011 - v1
Checksum:iF33C598161EF9141
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN869859 Genomic DNA. Translation: CCC82160.1.
RefSeqiWP_014127414.1. NC_016070.1.
YP_004893238.1. NC_016070.1.

Genome annotation databases

EnsemblBacteriaiCCC82160; CCC82160; TTX_1534.
GeneIDi11262412.
KEGGittn:TTX_1534.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN869859 Genomic DNA. Translation: CCC82160.1 .
RefSeqi WP_014127414.1. NC_016070.1.
YP_004893238.1. NC_016070.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CCC82160 ; CCC82160 ; TTX_1534 .
GeneIDi 11262412.
KEGGi ttn:TTX_1534.

Phylogenomic databases

KOi K00150.
OMAi VTVPSHH.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00184 .
BioCyci TTEN768679:GJSY-1508-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00559. G3P_dehdrog_arch.
InterProi IPR020831. GlycerAld/Erythrose_P_DH.
IPR020830. GlycerAld_3-P_DH_AS.
IPR020829. GlycerAld_3-P_DH_cat.
IPR020828. GlycerAld_3-P_DH_NAD(P)-bd.
IPR006436. Glyceraldehyde-3-P_DH_2_arc.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF02800. Gp_dh_C. 1 hit.
PF00044. Gp_dh_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000149. GAP_DH. 1 hit.
SMARTi SM00846. Gp_dh_N. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR01546. GAPDH-II_archae. 1 hit.
PROSITEi PS00071. GAPDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35583 / NBRC 100435 / JCM 9277 / Kra 1.

Entry informationi

Entry nameiG4RKR5_THETK
AccessioniPrimary (citable) accession number: G4RKR5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: September 3, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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