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G4RFZ7

- G4RFZ7_PELHB

UniProt

G4RFZ7 - G4RFZ7_PELHB

Protein

Alanine racemase

Gene

KKY_1005

Organism
Pelagibacterium halotolerans (strain JCM 15775 / CGMCC 1.7692 / B2)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 25 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei40 – 401Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei138 – 1381SubstrateUniRule annotation
    Active sitei259 – 2591Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei312 – 3121Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPHAL1082931:GJXT-1002-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:KKY_1005Imported
    OrganismiPelagibacterium halotolerans (strain JCM 15775 / CGMCC 1.7692 / B2)Imported
    Taxonomic identifieri1082931 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesHyphomicrobiaceaePelagibacterium
    ProteomesiUP000008850: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei40 – 401N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG4RFZ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.
    OMAiTRIAIMA.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G4RFZ7-1 [UniParc]FASTAAdd to Basket

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    MTSSKSILGG GITIDLDAIV RNWKALDTVS GKSLTGAVLK ADGYGTGAKT    50
    VGRALYKAGA RFFFVATPDE GVVLREAIPN AFIFVLDGLI PRTAADYAAH 100
    GLMPVLASMS QLTEWLDFCL NRGKAAPAAL HFDTGFNRVG FRMKEAELVA 150
    RELKQSGFEP QMIMSHFACA DQPSHEMTRK QNGLFQGLLN HFPDVPASIA 200
    NSAAVMSSKD YHYHLVRPGI AMYGGRAING RPNPMAPVIS MDVPILQIKD 250
    ARIGETVGYG AAYRLRRDTR IAIMALGYAD GYFRGLSGIG GQMGGRVAVN 300
    GTIVPVLGRI SMDMTAIDIT DVQGLVQPGD PVEILGPNIS IDDVADAART 350
    IGYEVLTTLN GRFPRSYINV PDGVSLD 377
    Length:377
    Mass (Da):40,364
    Last modified:December 14, 2011 - v1
    Checksum:iEB58639950F343AA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003075 Genomic DNA. Translation: AEQ51040.1.
    RefSeqiWP_014130189.1. NC_016078.1.
    YP_004898790.1. NC_016078.1.

    Genome annotation databases

    EnsemblBacteriaiAEQ51040; AEQ51040; KKY_1005.
    GeneIDi11345225.
    KEGGiphl:KKY_1005.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003075 Genomic DNA. Translation: AEQ51040.1 .
    RefSeqi WP_014130189.1. NC_016078.1.
    YP_004898790.1. NC_016078.1.

    3D structure databases

    ProteinModelPortali G4RFZ7.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEQ51040 ; AEQ51040 ; KKY_1005 .
    GeneIDi 11345225.
    KEGGi phl:KKY_1005.

    Phylogenomic databases

    KOi K01775.
    OMAi TRIAIMA.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci PHAL1082931:GJXT-1002-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JCM 15775 / CGMCC 1.7692 / B2Imported.

    Entry informationi

    Entry nameiG4RFZ7_PELHB
    AccessioniPrimary (citable) accession number: G4RFZ7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 25 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3