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G4R3K6 (G4R3K6_STRPY) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu HAMAP-Rule MF_00118

Short name=EF-Tu HAMAP-Rule MF_00118
Gene names
Name:tuf HAMAP-Rule MF_00118 EMBL AEQ24143.1
ORF Names:SPYALAB49_000539 EMBL AEQ24143.1
OrganismStreptococcus pyogenes Alab49 [Complete proteome] EMBL AEQ24143.1
Taxonomic identifier487215 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118 RuleBase RU000325

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. HAMAP-Rule MF_00118 RuleBase RU000325

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding19 – 268GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding84 – 885GTP By similarity HAMAP-Rule MF_00118
Nucleotide binding139 – 1424GTP By similarity HAMAP-Rule MF_00118

Sequences

Sequence LengthMass (Da)Tools
G4R3K6 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 95FCB3D69013C6FA

FASTA39843,826
        10         20         30         40         50         60 
MAKEKYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLARRL PSSVNQPKDY ASIDAAPEER 

        70         80         90        100        110        120 
ERGITINTAH VEYETATRHY AHIDAPGHAD YVKNMITGAA QMDGAILVVA STDGPMPQTR 

       130        140        150        160        170        180 
EHILLSRQVG VKHLIVFMNK VDLVDDEELL ELVEMEIRDL LSEYDFPGDD LPVIQGSALK 

       190        200        210        220        230        240 
ALEGDTKFED IIMELMDTVD SYIPEPERDT DKPLLLPVED VFSITGRGTV ASGRIDRGTV 

       250        260        270        280        290        300 
RVNDEIEIVG IKEETKKAVV TGVEMFRKQL DEGLAGDNVG ILLRGVQRDE IERGQVIAKP 

       310        320        330        340        350        360 
GSINPHTKFK GEVYILSKDE GGRHTPFFNN YRPQFYFRTT DVTGSIELPA GTEMVMPGDN 

       370        380        390 
VTINVELIHP IAVEQGTTFS IREGGRTVGS GIVSEIEA 

« Hide

References

[1]"Whole Genome Association Study on Tissue Tropism Phenotypes in Group A Streptococcus."
Bessen D.E., Kumar N., Hall G.S., Riley D.R., Luo F., Lizano S., Ford C.N., McShan W.M., Nguyen S.V., Dunning Hotopp J.C., Tettelin H.
J. Bacteriol. 193:6651-6663(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Alab49 EMBL AEQ24143.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003068 Genomic DNA. Translation: AEQ24143.1.
RefSeqYP_006071697.1. NC_017596.1.

3D structure databases

ProteinModelPortalG4R3K6.
SMRG4R3K6. Positions 2-396.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEG4R3K6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEQ24143; AEQ24143; SPYALAB49_000539.
GeneID12655730.
KEGGstz:SPYALAB49_000539.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK02358.

Enzyme and pathway databases

BioCycSPYO487215:GLLD-544-MONOMER.

Family and domain databases

HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4R3K6_STRPY
AccessionPrimary (citable) accession number: G4R3K6
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: February 19, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)