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G4QWE5

- G4QWE5_CORPS

UniProt

G4QWE5 - G4QWE5_CORPS

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Protein
Submitted name: Isocitrate dehydrogenase [NADP]
Gene
icd, Cp4202_0451
Organism
Corynebacterium pseudotuberculosis 42/02-A
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei143 – 1431Substrate By similarityUniRule annotation
Sitei252 – 2521Critical for catalysis By similarityUniRule annotation
Metal bindingi345 – 3451Magnesium or manganese By similarityUniRule annotation
Sitei415 – 4151Critical for catalysis By similarity
Binding sitei542 – 5421Substrate By similarityUniRule annotation
Metal bindingi543 – 5431Magnesium or manganese By similarityUniRule annotation
Metal bindingi547 – 5471Magnesium or manganese By similarityUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciCPSE1087453:GLBV-467-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP]Imported
Gene namesi
Name:icdImported
ORF Names:Cp4202_0451Imported
OrganismiCorynebacterium pseudotuberculosis 42/02-AImported
Taxonomic identifieri1087453 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000002656: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni130 – 1378Substrate binding By similarityUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

G4QWE5-1 [UniParc]FASTAAdd to Basket

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MAKIIYTRTD EAPLLATYSL KPVVEAFAST AGIEVETRDI SLAGRILSQF    50
PEFLTEDQKV DDALAELGEL AKTPEANIIK LPNISASVPQ LKAAVTELQS 100
QGYKLPNYPD SPSTEEEKDI RARYDAVKGS AVNPVLREGN SDRRAPIAVK 150
NFAKKHPHRM GAWSADSKTN VVTMESNDFR HNEKSVIMPD NDTLTIKLVT 200
DNGEKVLKDG LKVLKGEVVD GTFISARALD EFLADQVKRA KDEGVLFSAH 250
LKATMMKVSD PIIFGHVVRA YFADVFAKYG EQLEAAGLNG ENGLAAIYSG 300
LESLPNGAEI KAAFDEALES GADIAMVNSA KGITNLHVPS DVIIDASMPA 350
MIRTSGHMWN KNDEEQDTLA VIPDSSYAGV YQTVIADCKK NGAFDPTTMG 400
TVPNVGLMAQ KAEEYGSHDK TFKIEANGTV QVVSSAGEVL IEHNVEAGDI 450
WRACQAKDAP IQDWVKLAVT RSRLSGMPAV FWLDPERAHD RNLAALVEKY 500
LADHDTEGLD IHIMSPVEAT QFSIDRIRRG EDTISVTGNV LRDYNTDLFP 550
ILELGTSAKM LSVVPLMAGG GLFETGAGGS APKHVQQLVK ENHLRWDSLG 600
EFLALAESLR HFANTEGNTK AGILADTLDR ATETLLNEGY SPSRKAGEID 650
NRGSHFFLTK FWAKELSIQS EDADLAATFT PVAEALETHS EDIADALLAV 700
QGAPADLGGY YHPDDAKTTA VMRPVASYND IISSIK 736
Length:736
Mass (Da):79,815
Last modified:December 14, 2011 - v1
Checksum:i3797F15423600831
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003062 Genomic DNA. Translation: AEP69717.1.
RefSeqiWP_014522796.1. NC_017306.1.
YP_005691979.1. NC_017306.1.

Genome annotation databases

EnsemblBacteriaiAEP69717; AEP69717; Cp4202_0451.
GeneIDi12851657.
KEGGicos:Cp4202_0451.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP003062 Genomic DNA. Translation: AEP69717.1 .
RefSeqi WP_014522796.1. NC_017306.1.
YP_005691979.1. NC_017306.1.

3D structure databases

ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEP69717 ; AEP69717 ; Cp4202_0451 .
GeneIDi 12851657.
KEGGi cos:Cp4202_0451.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci CPSE1087453:GLBV-467-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 42/02-AImported.

Entry informationi

Entry nameiG4QWE5_CORPS
AccessioniPrimary (citable) accession number: G4QWE5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: September 3, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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