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G4QPV2 (G4QPV2_CORPS) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
ORF Names:CpCIP5297_0933 EMBL AEQ06472.1
OrganismCorynebacterium pseudotuberculosis CIP 52.97 EMBL AEQ06472.1
Taxonomic identifier935697 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium ›

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS000291

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS000291

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS000291

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS000291

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS000291.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047 SAAS SAAS000291

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain151 – 355205ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding178 – 23356ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3101Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3221Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3221Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3241Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
G4QPV2 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 1BD0BF1AC4AD7873

FASTA36038,980
        10         20         30         40         50         60 
MTQKPSPNPR VRVAVVYGGQ SSEHSVSCVS AGAIMSHLDP QKYEVFPVGI TRDGVWTVGE 

        70         80         90        100        110        120 
SDATKLRTVD RVMPEVEFVR EVKLSVNPRS AGELRYEDGT LYAQADVIFP ALHGRFGEDG 

       130        140        150        160        170        180 
TIQGMFELSG IPYVGTGVLS SACGMDKEYT KKLLAAEGLP VGKEVILRGD ETLTESDKQI 

       190        200        210        220        230        240 
LGLPVFVKPA RGGSSIGISR VIEWEDFDAA LTLAREHDTK VIVEAEIKGV EVECGVLERA 

       250        260        270        280        290        300 
DGSLIASVPA QLEDVDEGEE GFYGFDTKYL DNIVTATIPA PFDQQTIALI QSLSLEAFQA 

       310        320        330        340        350        360 
LNCRGLSRVD FFVTDQGPVL NEVNTMPGFT PISMYPQVFE ATGIGYAELL SHLIDQALAQ

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003061 Genomic DNA. Translation: AEQ06472.1.
RefSeqYP_005694495.1. NC_017307.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEQ06472; AEQ06472; CpCIP5297_0933.
GeneID12854131.
KEGGcoi:CpCIP5297_0933.

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycCPSE935697:GLBX-956-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4QPV2_CORPS
AccessionPrimary (citable) accession number: G4QPV2
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: May 29, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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