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G4QMD9 (G4QMD9_GLANF) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:GNIT_2694 EMBL AEP30791.1
OrganismGlaciecola nitratireducens (strain JCM 12485 / KCTC 12276 / FR1064) [Complete proteome] [HAMAP] EMBL AEP30791.1
Taxonomic identifier1085623 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceaeGlaciecola

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain123 – 325203ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding156 – 21156ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2791Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2921Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2921Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2941Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
G4QMD9 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 72B63D74DD68C85C

FASTA32935,056
        10         20         30         40         50         60 
MNQRVNSVNE KSATDIGAIS KDVFGKVAVL FGGNSAERKV SLASGTAVLN ALQAAGVDAH 

        70         80         90        100        110        120 
KFDPAENPIG DLIALGFDRA FIILHGRGGE DGSMQGALQL LGIPYTGTGV LGSALAMDKV 

       130        140        150        160        170        180 
YSKQVWSTLA LPTAPYKVLT KDQVNAALKP DYAALLAKLS GVAMVKPARE GSSIGMAKVS 

       190        200        210        220        230        240 
QPDELESAVK QALEYDDDVL IEQYINGPEY TVTILNGVAL PSIRMATPHV FYDYDAKYND 

       250        260        270        280        290        300 
KTTEYHCPSG LDDTTEKQVG QLALSAFQGL SGRGWGRVDL MRNEHGEFML LESNTVPGMT 

       310        320 
ETSLVPKAAK QAGLSFEQLV LQVLTSSLE 

« Hide

References

[1]"Complete Genome Sequence of Seawater Bacterium Glaciecola nitratireducens FR1064T."
Bian F., Qin Q.L., Xie B.B., Shu Y.L., Zhang X.Y., Yu Y., Chen B., Chen X.L., Zhou B.C., Zhang Y.Z.
J. Bacteriol. 193:7006-7007(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 12485 / KCTC 12276 / FR1064.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP003060 Genomic DNA. Translation: AEP30791.1.
RefSeqYP_004872784.1. NC_016041.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEP30791; AEP30791; GNIT_2694.
GeneID11182161.
KEGGgni:GNIT_2694.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycGNIT1085623:GJU2-2694-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4QMD9_GLANF
AccessionPrimary (citable) accession number: G4QMD9
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: February 19, 2014
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)