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G4QJ27 (G4QJ27_GLANF) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Gamma-glutamyl phosphate reductase HAMAP-Rule MF_00412
Short name=GPR HAMAP-Rule MF_00412
EC=1.2.1.41 HAMAP-Rule MF_00412
Alternative name(s):
Glutamate-5-semialdehyde dehydrogenase HAMAP-Rule MF_00412
Glutamyl-gamma-semialdehyde dehydrogenase HAMAP-Rule MF_00412
Gene names
Name:proA HAMAP-Rule MF_00412 EMBL AEP28895.1
Synonyms:proA1
Ordered Locus Names:GNIT_0751 EMBL AEP28895.1
OrganismGlaciecola nitratireducens (strain JCM 12485 / KCTC 12276 / FR1064) [Complete proteome] [HAMAP]
Taxonomic identifier1085623 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Alteromonadaceae › Glaciecola ›

Protein attributes

Sequence length415 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate By similarity. HAMAP-Rule MF_00412 SAAS SAAS020593

Catalytic activity

L-glutamate 5-semialdehyde + phosphate + NADP+ = L-glutamyl 5-phosphate + NADPH. HAMAP-Rule MF_00412 SAAS SAAS020593

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2. HAMAP-Rule MF_00412 SAAS SAAS020593

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00412 SAAS SAAS020593.

Sequence similarities

Belongs to the gamma-glutamyl phosphate reductase family. HAMAP-Rule MF_00412

Sequences

Sequence LengthMass (Da)Tools
G4QJ27 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 76916448BB2540A5

FASTA41545,220
        10         20         30         40         50         60 
MSLIKDLSRK AAEAAQILSV LDEAEKNAVL MDMAKTLRDN ANGIIENNAK DLVNAKNNDL 

        70         80         90        100        110        120 
AASMIDRLTL NQERIEAMAE GLETVAILPD PVGVERDLGT RPNGLQIRKM RVPLGVVCMI 

       130        140        150        160        170        180 
YEARPNVTAD AAGLCFKSGN AAILRGGKEA LESSLFIANL LQDVLEKHNL PRELISVVPN 

       190        200        210        220        230        240 
ADRALMQELM EQKDYIDVII PRGGEGLINY VTENSKVPVI QHFKGVCHLY IDKEADIETA 

       250        260        270        280        290        300 
INLLVNGKTQ RTGVCNALEG LLVHEDIAEE FLSVAGPILE EHSVKVNSCE NSSKYFNNST 

       310        320        330        340        350        360 
VIKTDGFGEE YLDLEIAVRI VPTIEGAMQH IARFGSHHTE VICTKNELTA KRFQRTVDSS 

       370        380        390        400        410 
VVMVNASSRF SDGSQLGLGA EIGIATTKLH AYGPMGLESL TTEKYLVNGV GQVRA

« Hide

References

[1]"Complete genome sequence of seawater bacterium Glaciecola nitratireducens FR1064T."
Bian F., Qin Q.L., Xie B.B., Shu Y.L., Zhang X.Y., Yu Y., Chen B., Chen X.L., Zhou B.C., Zhang Y.Z.
J. Bacteriol. 193:7006-7007(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 12485 / KCTC 12276 / FR1064.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP003060 Genomic DNA. Translation: AEP28895.1.
RefSeqYP_004870888.1. NC_016041.1.

3D structure databases

ProteinModelPortalG4QJ27.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEP28895; AEP28895; GNIT_0751.
GeneID11180142.
KEGGgni:GNIT_0751.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00147.

Enzyme and pathway databases

BioCycGNIT1085623:GJU2-751-MONOMER.
UniPathwayUPA00098; UER00360.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 2 hits.
HAMAPMF_00412. ProA.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR000965. G-glutamylP_reductase.
IPR020593. G-glutamylP_reductase_CS.
IPR012134. Glu-5-SA_DH.
[Graphical view]
PANTHERPTHR11063:SF1. PTHR11063:SF1. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
PIRSFPIRSF000151. GPR. 1 hit.
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR00407. proA. 1 hit.
PROSITEPS01223. PROA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4QJ27_GLANF
AccessionPrimary (citable) accession number: G4QJ27
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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