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G4QCP2

- G4QCP2_TAYAM

UniProt

G4QCP2 - G4QCP2_TAYAM

Protein
Submitted name:

Isocitrate dehydrogenase [NADP]

Gene

TASI_0396

Organism
Taylorella asinigenitalis (strain MCE3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 19 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei144 – 1441SubstrateUniRule annotation
    Sitei254 – 2541Critical for catalysisUniRule annotation
    Metal bindingi347 – 3471Magnesium or manganeseUniRule annotation
    Sitei417 – 4171Critical for catalysisUniRule annotation
    Binding sitei544 – 5441SubstrateUniRule annotation
    Metal bindingi545 – 5451Magnesium or manganeseUniRule annotation
    Metal bindingi549 – 5491Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciTASI1008459:GH5G-395-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase [NADP]Imported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:TASI_0396Imported
    OrganismiTaylorella asinigenitalis (strain MCE3)Imported
    Taxonomic identifieri1008459 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeTaylorella
    ProteomesiUP000009284: Chromosome

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni131 – 1388Substrate bindingUniRule annotation

    Phylogenomic databases

    KOiK00031.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G4QCP2-1 [UniParc]FASTAAdd to Basket

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    MTTTISYTFT DEAPMLATHS FLPIVKAFTS VADIKVETKD ISLAGRILAV    50
    MGDYLKDDQK TADALAELGE LAGKPEANII KLPNISASIP QLNEAIAELQ 100
    KQGFALPDYP AEPKNDEEKK IKSLYAKVLG SAVNPVLREG NSDRRAPKAV 150
    KNYARKNPHS MGIWNADSKT KVLHMNEGDF YASEKSLTLE EPSDFAIVHV 200
    AHDGTKTELR PSAKLEAGEV LDSSVMSMEA LKAFVREAKE EAAREDVLFS 250
    AHLKATMMKV SDPIIFGAIV EVYFADVFEK FADVFDELGV NPNNGLGELF 300
    AKIEGHAKEA VIKAAIEAAI DEGPDIAMVN SDKGITNLHV PSDVIVDASM 350
    PAMIRSSGQM WNKDGKLQDT FALLPDRSYA ELYNVVIEDC KRNGAFDPTT 400
    MGSVPNVGLM AKKAEEYGSH DKTFQATADG VIQAVDSSGR VLLEQEVRAG 450
    DIYRMCQTKD APIKDWVKLA VNRARLSETP VVFWLDDARA HDREIIAKVR 500
    KYLADHDTTG LQIEVMSPVN AMEFSLERIR KGEDTISATG NVLRDYLTDL 550
    FPILELGTSA KMLSIVPLMN GGGLFETGAG GSAPKHIEQF IEEGYLRWDS 600
    LGEFLALQAS LEHIANTSDN KKAQILADAL DEANAQFLDN NRSPGRKLGT 650
    IDNRGSHYYL AMYWAQALAD QTEDAEIASK FSEIAAKLAS AEEQINKELI 700
    GAQGSAQDIG GYYKPDPEKT TRAMRPSETL NQIIDAI 737
    Length:737
    Mass (Da):80,628
    Last modified:December 14, 2011 - v1
    Checksum:iCC0583048E7977CF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003059 Genomic DNA. Translation: AEP36172.1.
    RefSeqiWP_014111070.1. NC_016043.1.
    YP_004874195.1. NC_016043.1.

    Genome annotation databases

    EnsemblBacteriaiAEP36172; AEP36172; TASI_0396.
    GeneIDi11186860.
    KEGGitas:TASI_0396.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003059 Genomic DNA. Translation: AEP36172.1 .
    RefSeqi WP_014111070.1. NC_016043.1.
    YP_004874195.1. NC_016043.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEP36172 ; AEP36172 ; TASI_0396 .
    GeneIDi 11186860.
    KEGGi tas:TASI_0396.

    Phylogenomic databases

    KOi K00031.

    Enzyme and pathway databases

    BioCyci TASI1008459:GH5G-395-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genomic characterization of the Taylorella genus."
      Hebert L., Moumen B., Pons N., Duquesne F., Breuil M.-F., Goux D., Batto J.-M., Renault P., Laugier C., Petry S.
      Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MCE3.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MCE3Imported.

    Entry informationi

    Entry nameiG4QCP2_TAYAM
    AccessioniPrimary (citable) accession number: G4QCP2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 19 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3