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G4QCP2

- G4QCP2_TAYAM

UniProt

G4QCP2 - G4QCP2_TAYAM

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Protein
Submitted name:

Isocitrate dehydrogenase [NADP]

Gene

TASI_0396

Organism
Taylorella asinigenitalis (strain MCE3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei144 – 1441SubstrateUniRule annotation
Sitei254 – 2541Critical for catalysisUniRule annotation
Metal bindingi347 – 3471Magnesium or manganeseUniRule annotation
Sitei417 – 4171Critical for catalysisUniRule annotation
Binding sitei544 – 5441SubstrateUniRule annotation
Metal bindingi545 – 5451Magnesium or manganeseUniRule annotation
Metal bindingi549 – 5491Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTASI1008459:GH5G-395-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP]Imported (EC:1.1.1.42Imported)
Gene namesi
Ordered Locus Names:TASI_0396Imported
OrganismiTaylorella asinigenitalis (strain MCE3)Imported
Taxonomic identifieri1008459 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesAlcaligenaceaeTaylorella
ProteomesiUP000009284: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni131 – 1388Substrate bindingUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

G4QCP2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTTTISYTFT DEAPMLATHS FLPIVKAFTS VADIKVETKD ISLAGRILAV
60 70 80 90 100
MGDYLKDDQK TADALAELGE LAGKPEANII KLPNISASIP QLNEAIAELQ
110 120 130 140 150
KQGFALPDYP AEPKNDEEKK IKSLYAKVLG SAVNPVLREG NSDRRAPKAV
160 170 180 190 200
KNYARKNPHS MGIWNADSKT KVLHMNEGDF YASEKSLTLE EPSDFAIVHV
210 220 230 240 250
AHDGTKTELR PSAKLEAGEV LDSSVMSMEA LKAFVREAKE EAAREDVLFS
260 270 280 290 300
AHLKATMMKV SDPIIFGAIV EVYFADVFEK FADVFDELGV NPNNGLGELF
310 320 330 340 350
AKIEGHAKEA VIKAAIEAAI DEGPDIAMVN SDKGITNLHV PSDVIVDASM
360 370 380 390 400
PAMIRSSGQM WNKDGKLQDT FALLPDRSYA ELYNVVIEDC KRNGAFDPTT
410 420 430 440 450
MGSVPNVGLM AKKAEEYGSH DKTFQATADG VIQAVDSSGR VLLEQEVRAG
460 470 480 490 500
DIYRMCQTKD APIKDWVKLA VNRARLSETP VVFWLDDARA HDREIIAKVR
510 520 530 540 550
KYLADHDTTG LQIEVMSPVN AMEFSLERIR KGEDTISATG NVLRDYLTDL
560 570 580 590 600
FPILELGTSA KMLSIVPLMN GGGLFETGAG GSAPKHIEQF IEEGYLRWDS
610 620 630 640 650
LGEFLALQAS LEHIANTSDN KKAQILADAL DEANAQFLDN NRSPGRKLGT
660 670 680 690 700
IDNRGSHYYL AMYWAQALAD QTEDAEIASK FSEIAAKLAS AEEQINKELI
710 720 730
GAQGSAQDIG GYYKPDPEKT TRAMRPSETL NQIIDAI
Length:737
Mass (Da):80,628
Last modified:December 14, 2011 - v1
Checksum:iCC0583048E7977CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003059 Genomic DNA. Translation: AEP36172.1.
RefSeqiWP_014111070.1. NC_016043.1.
YP_004874195.1. NC_016043.1.

Genome annotation databases

EnsemblBacteriaiAEP36172; AEP36172; TASI_0396.
GeneIDi11186860.
KEGGitas:TASI_0396.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP003059 Genomic DNA. Translation: AEP36172.1 .
RefSeqi WP_014111070.1. NC_016043.1.
YP_004874195.1. NC_016043.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEP36172 ; AEP36172 ; TASI_0396 .
GeneIDi 11186860.
KEGGi tas:TASI_0396.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci TASI1008459:GH5G-395-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Genomic characterization of the Taylorella genus."
    Hebert L., Moumen B., Pons N., Duquesne F., Breuil M.-F., Goux D., Batto J.-M., Renault P., Laugier C., Petry S.
    Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MCE3.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: MCE3Imported.

Entry informationi

Entry nameiG4QCP2_TAYAM
AccessioniPrimary (citable) accession number: G4QCP2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: November 26, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3