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G4PUJ3

- G4PUJ3_ECOLX

UniProt

G4PUJ3 - G4PUJ3_ECOLX

Protein

Thymidine kinase

Gene

tdk

Organism
Escherichia coli O7:K1 str. CE10
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 14 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciECOL1072459:GLD5-1416-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkImported
    ORF Names:CE10_1416Imported
    OrganismiEscherichia coli O7:K1 str. CE10Imported
    Taxonomic identifieri1072459 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000002657: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G4PUJ3-1 [UniParc]FASTAAdd to Basket

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    MRTVVYTAEI DDRFGAGKVS SRIGLSSPAK LFNQNSSLFD EIRAEHEQQA    50
    IHCVLVDECQ FLTRQQVYEL SEVVDQLDIP VLCYGLRTDF RGELFIGSQY 100
    LLAWSDKLVE LKTICFCGRK ASMVLRLDQA GRPYNEGEQV VIGGNERYVS 150
    VCRKHYKEAL EVGSLTAIQE RHRHD 175
    Length:175
    Mass (Da):19,961
    Last modified:December 14, 2011 - v1
    Checksum:i25E4636632F73BCF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003034 Genomic DNA. Translation: AEQ12227.1.
    RefSeqiYP_006143511.1. NC_017646.1.

    Genome annotation databases

    EnsemblBacteriaiAEQ12227; AEQ12227; CE10_1416.
    GeneIDi12674221.
    KEGGieoc:CE10_1416.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP003034 Genomic DNA. Translation: AEQ12227.1 .
    RefSeqi YP_006143511.1. NC_017646.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEQ12227 ; AEQ12227 ; CE10_1416 .
    GeneIDi 12674221.
    KEGGi eoc:CE10_1416.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci ECOL1072459:GLD5-1416-MONOMER.

    Family and domain databases

    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of the Neonatal-Meningitis-Associated Escherichia coli Strain CE10."
      Lu S., Zhang X., Zhu Y., Kim K.S., Yang J., Jin Q.
      J. Bacteriol. 193:7005-7005(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CE10Imported.

    Entry informationi

    Entry nameiG4PUJ3_ECOLX
    AccessioniPrimary (citable) accession number: G4PUJ3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 14 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3