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G4NZV6 (G4NZV6_BACPN) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2-succinylbenzoate--CoA ligase HAMAP-Rule MF_00731

EC=6.2.1.26 HAMAP-Rule MF_00731
Alternative name(s):
OSB-CoA synthetase HAMAP-Rule MF_00731
o-succinylbenzoyl-CoA synthetase HAMAP-Rule MF_00731
Gene names
Name:menE HAMAP-Rule MF_00731 EMBL AEP87935.1
ORF Names:GYO_3333 EMBL AEP87935.1
OrganismBacillus subtilis subsp. spizizenii TU-B-10 EMBL AEP87935.1
Taxonomic identifier1052585 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length486 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA) By similarity. HAMAP-Rule MF_00731

Catalytic activity

ATP + 2-succinylbenzoate + CoA = AMP + diphosphate + 2-succinylbenzoyl-CoA. HAMAP-Rule MF_00731

Pathway

Cofactor biosynthesis; menaquinone biosynthesis; menaquinone-2 from chorismate: step 5/8. HAMAP-Rule MF_00731

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. HAMAP-Rule MF_00731

Sequences

Sequence LengthMass (Da)Tools
G4NZV6 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 1B09EF822651C462

FASTA48653,980
        10         20         30         40         50         60 
MLTEQPNWLM QRAQLTPERI ALIYGDQTVT FAELFAASKR MAAQLGAHSV RKGDTAAILL 

        70         80         90        100        110        120 
QNRAEMVYAV HACFLLGVKA VLLNTKLSTH ERLFQLKDSG ARFLLTDSNF DQQDYEHTVQ 

       130        140        150        160        170        180 
TIDVDELMKE AAKEIEIQAY MQLDETATLM YTSGTTGKPK GVQQTFGNHY FSAVSSALNL 

       190        200        210        220        230        240 
GITEQDRWLI ALPLFHISGL SALFKSVIYG MTVVLHQRFS VSDVLDSISR HQVTMISAVQ 

       250        260        270        280        290        300 
TMLASLLEET SRCPESIRCI LLGGGPAPLP LLEECREKGF PVFQSYGMTE TCSQIVTLSP 

       310        320        330        340        350        360 
EFSMEKLGSA GKPLFSCEIK IERDGQACEP FEHGEILVKG PNVMKSYFNR ESANESSFQN 

       370        380        390        400        410        420 
GWLKTGDLGY LDSEGFLYVL DRRSDLIISG GENIYPAEVE SVLLSHPAVA EAGVSGAEDK 

       430        440        450        460        470        480 
KWGKVPHAYL VLHKPVSAEE LTAYCKERLA KYKIPAKFFV LDSLPRNASN KLMRNQLKDA 


RKGELL 

« Hide

References

[1]"Whole-Genome Sequences of Bacillus subtilis and Close Relatives."
Earl A.M., Eppinger M., Fricke W.F., Rosovitz M.J., Rasko D.A., Daugherty S., Losick R., Kolter R., Ravel J.
J. Bacteriol. 194:2378-2379(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: TU-B-10 EMBL AEP87935.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002905 Genomic DNA. Translation: AEP87935.1.
RefSeqYP_004878567.1. NC_016047.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEP87935; AEP87935; GYO_3333.
GeneID11240664.
KEGGbst:GYO_3333.

Phylogenomic databases

KOK01911.

Enzyme and pathway databases

BioCycBSUB1052585:GJWW-3300-MONOMER.
UniPathwayUPA00079; UER00166.

Family and domain databases

HAMAPMF_00731. MenE.
InterProIPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
IPR025110. DUF4009.
IPR010192. MenE.
IPR023015. SB_CoA_ligase_firmicutes.
[Graphical view]
PfamPF00501. AMP-binding. 1 hit.
PF13193. DUF4009. 1 hit.
[Graphical view]
TIGRFAMsTIGR01923. menE. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4NZV6_BACPN
AccessionPrimary (citable) accession number: G4NZV6
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 3, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)