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G4NS43 (G4NS43_BACPN) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferase HAMAP-Rule MF_00038
EC=2.7.8.13 HAMAP-Rule MF_00038
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferase HAMAP-Rule MF_00038
Gene names
Name:mraY HAMAP-Rule MF_00038 EMBL AEP86504.1
ORF Names:GYO_1865 EMBL AEP86504.1
OrganismBacillus subtilis subsp. spizizenii TU-B-10 EMBL AEP86504.1
Taxonomic identifier1052585 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan By similarity. HAMAP-Rule MF_00038

Catalytic activity

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP-Rule MF_00038

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00038

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00038.

Sequence similarities

Belongs to the glycosyltransferase 4 family. MraY subfamily. HAMAP-Rule MF_00038

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane5 – 2521Helical; By similarity HAMAP-Rule MF_00038
Transmembrane50 – 7021Helical; By similarity HAMAP-Rule MF_00038
Transmembrane77 – 9721Helical; By similarity HAMAP-Rule MF_00038
Transmembrane117 – 13721Helical; By similarity HAMAP-Rule MF_00038
Transmembrane147 – 16721Helical; By similarity HAMAP-Rule MF_00038
Transmembrane176 – 19621Helical; By similarity HAMAP-Rule MF_00038
Transmembrane203 – 22321Helical; By similarity HAMAP-Rule MF_00038
Transmembrane227 – 24721Helical; By similarity HAMAP-Rule MF_00038
Transmembrane250 – 27021Helical; By similarity HAMAP-Rule MF_00038
Transmembrane302 – 32221Helical; By similarity HAMAP-Rule MF_00038

Sequences

Sequence LengthMass (Da)Tools
G4NS43 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: CCA6F7048CB00DB6

FASTA32435,513
        10         20         30         40         50         60 
MLEQVILFTI LMGFLISVLL SPILIPFLRR LKFGQSIREE GPKSHQKKSG TPTMGGVMII 

        70         80         90        100        110        120 
LSIIVTTIVM TQKFSEISPE MVLLLFVTLG YGLLGFLDDY IKVVMKRNLG LTSKQKLIGQ 

       130        140        150        160        170        180 
IIIAVVFYAV YHYYNFATDI RVPGTDLSFD LGWAYFILVL FMLVGGSNAV NLTDGLDGLL 

       190        200        210        220        230        240 
SGTAAIAFGA FAILAWNQSQ YDVAIFSVAV VGAVLGFLVF NAHPAKVFMG DTGSLALGGA 

       250        260        270        280        290        300 
IVTIAILTKL EILLVIIGGV FVIETLSVIL QVISFKTTGK RIFKMSPLHH HYELVGWSEW 

       310        320 
RVVVTFWAAG LLLAVLGIYI EVWL

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References

[1]"Whole-Genome Sequences of Bacillus subtilis and Close Relatives."
Earl A.M., Eppinger M., Fricke W.F., Rosovitz M.J., Rasko D.A., Daugherty S., Losick R., Kolter R., Ravel J.
J. Bacteriol. 194:2378-2379(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: TU-B-10 EMBL AEP86504.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002905 Genomic DNA. Translation: AEP86504.1.
RefSeqYP_004877136.1. NC_016047.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEP86504; AEP86504; GYO_1865.
GeneID11239388.
KEGGbst:GYO_1865.

Phylogenomic databases

KOK01000.

Enzyme and pathway databases

BioCycBSUB1052585:GJWW-1848-MONOMER.
UniPathwayUPA00219.

Family and domain databases

HAMAPMF_00038. MraY.
InterProIPR000715. Glycosyl_transferase_4.
IPR003524. PNAcMuramoyl-5peptid_Trfase.
IPR018480. PNAcMuramoyl-5peptid_Trfase_CS.
[Graphical view]
PANTHERPTHR22926. PTHR22926. 1 hit.
PTHR22926:SF3. PTHR22926:SF3. 1 hit.
PfamPF00953. Glycos_transf_4. 1 hit.
PF10555. MraY_sig1. 1 hit.
[Graphical view]
TIGRFAMsTIGR00445. mraY. 1 hit.
PROSITEPS01347. MRAY_1. 1 hit.
PS01348. MRAY_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4NS43_BACPN
AccessionPrimary (citable) accession number: G4NS43
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 3, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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