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G4L2G2

- G4L2G2_TETHN

UniProt

G4L2G2 - G4L2G2_TETHN

Protein

Isoprenyl transferase

Gene

uppS

Organism
Tetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172) (Pediococcus halophilus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.UniRule annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi35 – 351MagnesiumUniRule annotation
    Binding sitei40 – 401SubstrateUniRule annotation
    Binding sitei48 – 481SubstrateUniRule annotation
    Binding sitei52 – 521SubstrateUniRule annotation
    Active sitei83 – 831Proton acceptorUniRule annotation
    Binding sitei84 – 841SubstrateUniRule annotation
    Binding sitei86 – 861SubstrateUniRule annotation
    Binding sitei207 – 2071SubstrateUniRule annotation
    Metal bindingi226 – 2261MagnesiumUniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. prenyltransferase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    TransferaseUniRule annotationImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciTHAL945021:GJV6-1985-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isoprenyl transferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
    Gene namesi
    Name:uppSImported
    Ordered Locus Names:TEH_19640Imported
    OrganismiTetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172) (Pediococcus halophilus)Imported
    Taxonomic identifieri945021 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeTetragenococcus
    ProteomesiUP000002663: Chromosome

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG4L2G2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UPP synthase family.UniRule annotation

    Phylogenomic databases

    KOiK00806.
    OMAiLNRLPRH.

    Family and domain databases

    Gene3Di3.40.1180.10. 1 hit.
    HAMAPiMF_01139. ISPT.
    InterProiIPR001441. UPP_synth-like.
    IPR018520. UPP_synth-like_CS.
    [Graphical view]
    PANTHERiPTHR10291. PTHR10291. 1 hit.
    PfamiPF01255. Prenyltransf. 1 hit.
    [Graphical view]
    SUPFAMiSSF64005. SSF64005. 1 hit.
    TIGRFAMsiTIGR00055. uppS. 1 hit.
    PROSITEiPS01066. UPP_SYNTHASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G4L2G2-1 [UniParc]FASTAAdd to Basket

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    MLRFFPEKNK TFQEEQEYTF DSELPVPKHI AIIMDGNGRW AQNRRLPRVA    50
    GHKEGMETVK KITKHASYLG VKVLTLYAFS TENWRRPEEE VNFLMQLPVD 100
    FFDTFVPELM KENVRVNVMG EYDVLPAHTQ DAVNRAVKQT SENTGMILNF 150
    ALNYGSRAEM VSAVKNIATD ISAKNIEVEQ IDDDFIADYL MTGFLPKEIR 200
    DPEVLIRTSG EERISNFLLW QIAYSELLFT KELWPDYSEA SLENSIAIFQ 250
    HRNRRFGGLK NKEENK 266
    Length:266
    Mass (Da):30,879
    Last modified:December 14, 2011 - v1
    Checksum:iA89297E9ADDB925F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012046 Genomic DNA. Translation: BAK95291.1.
    RefSeqiYP_004887455.1. NC_016052.1.

    Genome annotation databases

    EnsemblBacteriaiBAK95291; BAK95291; TEH_19640.
    GeneIDi11260878.
    KEGGithl:TEH_19640.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012046 Genomic DNA. Translation: BAK95291.1 .
    RefSeqi YP_004887455.1. NC_016052.1.

    3D structure databases

    ProteinModelPortali G4L2G2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAK95291 ; BAK95291 ; TEH_19640 .
    GeneIDi 11260878.
    KEGGi thl:TEH_19640.

    Phylogenomic databases

    KOi K00806.
    OMAi LNRLPRH.

    Enzyme and pathway databases

    BioCyci THAL945021:GJV6-1985-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1180.10. 1 hit.
    HAMAPi MF_01139. ISPT.
    InterProi IPR001441. UPP_synth-like.
    IPR018520. UPP_synth-like_CS.
    [Graphical view ]
    PANTHERi PTHR10291. PTHR10291. 1 hit.
    Pfami PF01255. Prenyltransf. 1 hit.
    [Graphical view ]
    SUPFAMi SSF64005. SSF64005. 1 hit.
    TIGRFAMsi TIGR00055. uppS. 1 hit.
    PROSITEi PS01066. UPP_SYNTHASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Tetragenococcus halophilus NBRC 12172."
      Nakazawa H., Omata S., Koga C., Watanabe Y., Katano Y., Ito N., Tsukatani N., Ankai A., Oguchi A., Fukui S., Yashiro I., Kamata S., Hashimoto Y., Yamazaki J., Taguchi H., Tanaka A., Koyama T., Ichige A.
      , Hanya Y., Tanikawa S., Yamazaki S., Fujita N.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172Imported.

    Entry informationi

    Entry nameiG4L2G2_TETHN
    AccessioniPrimary (citable) accession number: G4L2G2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3