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G4L2G2

- G4L2G2_TETHN

UniProt

G4L2G2 - G4L2G2_TETHN

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Protein

Isoprenyl transferase

Gene
uppS, TEH_19640
Organism
Tetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172) (Pediococcus halophilus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids By similarity.UniRule annotation

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi35 – 351Magnesium By similarityUniRule annotation
Binding sitei40 – 401Substrate By similarityUniRule annotation
Binding sitei48 – 481Substrate By similarityUniRule annotation
Binding sitei52 – 521Substrate By similarityUniRule annotation
Active sitei83 – 831Proton acceptor By similarityUniRule annotation
Binding sitei84 – 841Substrate By similarityUniRule annotation
Binding sitei86 – 861Substrate By similarityUniRule annotation
Binding sitei207 – 2071Substrate By similarityUniRule annotation
Metal bindingi226 – 2261Magnesium By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. prenyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciTHAL945021:GJV6-1985-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isoprenyl transferaseUniRule annotation (EC:2.5.1.-UniRule annotation)
Gene namesi
Name:uppSImported
Ordered Locus Names:TEH_19640Imported
OrganismiTetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172) (Pediococcus halophilus)
Taxonomic identifieri945021 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeTetragenococcus
ProteomesiUP000002663: Chromosome

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG4L2G2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00806.
OMAiLNRLPRH.

Family and domain databases

Gene3Di3.40.1180.10. 1 hit.
HAMAPiMF_01139. ISPT.
InterProiIPR001441. UPP_synth-like.
IPR018520. UPP_synth-like_CS.
[Graphical view]
PANTHERiPTHR10291. PTHR10291. 1 hit.
PfamiPF01255. Prenyltransf. 1 hit.
[Graphical view]
SUPFAMiSSF64005. SSF64005. 1 hit.
TIGRFAMsiTIGR00055. uppS. 1 hit.
PROSITEiPS01066. UPP_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G4L2G2-1 [UniParc]FASTAAdd to Basket

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MLRFFPEKNK TFQEEQEYTF DSELPVPKHI AIIMDGNGRW AQNRRLPRVA    50
GHKEGMETVK KITKHASYLG VKVLTLYAFS TENWRRPEEE VNFLMQLPVD 100
FFDTFVPELM KENVRVNVMG EYDVLPAHTQ DAVNRAVKQT SENTGMILNF 150
ALNYGSRAEM VSAVKNIATD ISAKNIEVEQ IDDDFIADYL MTGFLPKEIR 200
DPEVLIRTSG EERISNFLLW QIAYSELLFT KELWPDYSEA SLENSIAIFQ 250
HRNRRFGGLK NKEENK 266
Length:266
Mass (Da):30,879
Last modified:December 14, 2011 - v1
Checksum:iA89297E9ADDB925F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012046 Genomic DNA. Translation: BAK95291.1.
RefSeqiYP_004887455.1. NC_016052.1.

Genome annotation databases

EnsemblBacteriaiBAK95291; BAK95291; TEH_19640.
GeneIDi11260878.
KEGGithl:TEH_19640.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012046 Genomic DNA. Translation: BAK95291.1 .
RefSeqi YP_004887455.1. NC_016052.1.

3D structure databases

ProteinModelPortali G4L2G2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAK95291 ; BAK95291 ; TEH_19640 .
GeneIDi 11260878.
KEGGi thl:TEH_19640.

Phylogenomic databases

KOi K00806.
OMAi LNRLPRH.

Enzyme and pathway databases

BioCyci THAL945021:GJV6-1985-MONOMER.

Family and domain databases

Gene3Di 3.40.1180.10. 1 hit.
HAMAPi MF_01139. ISPT.
InterProi IPR001441. UPP_synth-like.
IPR018520. UPP_synth-like_CS.
[Graphical view ]
PANTHERi PTHR10291. PTHR10291. 1 hit.
Pfami PF01255. Prenyltransf. 1 hit.
[Graphical view ]
SUPFAMi SSF64005. SSF64005. 1 hit.
TIGRFAMsi TIGR00055. uppS. 1 hit.
PROSITEi PS01066. UPP_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Whole genome sequence of Tetragenococcus halophilus NBRC 12172."
    Nakazawa H., Omata S., Koga C., Watanabe Y., Katano Y., Ito N., Tsukatani N., Ankai A., Oguchi A., Fukui S., Yashiro I., Kamata S., Hashimoto Y., Yamazaki J., Taguchi H., Tanaka A., Koyama T., Ichige A.
    , Hanya Y., Tanikawa S., Yamazaki S., Fujita N.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172.

Entry informationi

Entry nameiG4L2G2_TETHN
AccessioniPrimary (citable) accession number: G4L2G2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: June 11, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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