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G4KXA3

- G4KXA3_OSCVS

UniProt

G4KXA3 - G4KXA3_OSCVS

Protein

Thymidine kinase

Gene

tdk

Organism
Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (14 Dec 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei83 – 831Proton acceptorUniRule annotation
    Metal bindingi140 – 1401ZincUniRule annotation
    Metal bindingi142 – 1421ZincUniRule annotation
    Metal bindingi177 – 1771ZincUniRule annotation
    Metal bindingi180 – 1801ZincUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi82 – 854ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP
    3. zinc ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

    Enzyme and pathway databases

    BioCyciOVAL693746:GJWX-3769-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotationImported
    Ordered Locus Names:OBV_37130Imported
    OrganismiOscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)Imported
    Taxonomic identifieri693746 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesOscillospiraceaeOscillibacter
    ProteomesiUP000005219: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G4KXA3-1 [UniParc]FASTAAdd to Basket

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    MAQLYFKYGA MGSSKTANAL MTRFNYEERG QQTLLVKPRL DTRDGDHMVY    50
    SRIGLKHSCI YFDEMRRINP MELQQNACII VDEAQFLTKE EVDYLVSLVD 100
    DCGIPVICYG LRADFKGDLF PGSEELLVMA DKIEEVKTIC WCGKKATFNA 150
    RFDREGHVLK EGAQVVLGAN DQYIGLCRKH WRDGNLGPDF KAVQP 195
    Length:195
    Mass (Da):22,214
    Last modified:December 14, 2011 - v1
    Checksum:i8259F50A2045F908
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012044 Genomic DNA. Translation: BAL00912.1.
    RefSeqiYP_004883417.1. NC_016048.1.

    Genome annotation databases

    EnsemblBacteriaiBAL00912; BAL00912; OBV_37130.
    GeneIDi11235341.
    KEGGiova:OBV_37130.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP012044 Genomic DNA. Translation: BAL00912.1 .
    RefSeqi YP_004883417.1. NC_016048.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAL00912 ; BAL00912 ; OBV_37130 .
    GeneIDi 11235341.
    KEGGi ova:OBV_37130.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci OVAL693746:GJWX-3769-MONOMER.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Oscillibacter valericigenes Sjm18-20."
      Katano Y., Fujinami S., Kawakoshi A., Ohji S., Nakazawa H., Ankai A., Oguchi A., Fukui S., Terui Y., Harada T., Takahashi M., Suzuki K., Fujita N.
      Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 18026 / NBRC 101213 / Sjm18-20Imported.

    Entry informationi

    Entry nameiG4KXA3_OSCVS
    AccessioniPrimary (citable) accession number: G4KXA3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 14, 2011
    Last sequence update: December 14, 2011
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3