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Protein

Thymidine kinase

Gene

tdk

Organism
Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei83Proton acceptorUniRule annotation1
Metal bindingi140ZincUniRule annotation1
Metal bindingi142ZincUniRule annotation1
Metal bindingi177ZincUniRule annotation1
Metal bindingi180ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi82 – 85ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:OBV_37130Imported
OrganismiOscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)Imported
Taxonomic identifieri693746 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesOscillospiraceaeOscillibacter
Proteomesi
  • UP000005219 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi693746.OBV_37130

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107SV9 Bacteria
COG1435 LUCA
KOiK00857
OMAiKEQFGWI
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

G4KXA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLYFKYGA MGSSKTANAL MTRFNYEERG QQTLLVKPRL DTRDGDHMVY
60 70 80 90 100
SRIGLKHSCI YFDEMRRINP MELQQNACII VDEAQFLTKE EVDYLVSLVD
110 120 130 140 150
DCGIPVICYG LRADFKGDLF PGSEELLVMA DKIEEVKTIC WCGKKATFNA
160 170 180 190
RFDREGHVLK EGAQVVLGAN DQYIGLCRKH WRDGNLGPDF KAVQP
Length:195
Mass (Da):22,214
Last modified:December 14, 2011 - v1
Checksum:i8259F50A2045F908
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012044 Genomic DNA Translation: BAL00912.1
RefSeqiWP_014119509.1, NC_016048.1

Genome annotation databases

EnsemblBacteriaiBAL00912; BAL00912; OBV_37130
KEGGiova:OBV_37130
PATRICifig|693746.9.peg.4019

Similar proteinsi

Entry informationi

Entry nameiG4KXA3_OSCVS
AccessioniPrimary (citable) accession number: G4KXA3
Entry historyiIntegrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: March 28, 2018
This is version 35 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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