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G4KXA3

- G4KXA3_OSCVS

UniProt

G4KXA3 - G4KXA3_OSCVS

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Protein

Thymidine kinase

Gene
tdk, OBV_37130
Organism
Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei83 – 831Proton acceptor By similarityUniRule annotation
Metal bindingi140 – 1401Zinc By similarityUniRule annotation
Metal bindingi142 – 1421Zinc By similarityUniRule annotation
Metal bindingi177 – 1771Zinc By similarityUniRule annotation
Metal bindingi180 – 1801Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi82 – 854ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Enzyme and pathway databases

BioCyciOVAL693746:GJWX-3769-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotationImported
Ordered Locus Names:OBV_37130Imported
OrganismiOscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)Imported
Taxonomic identifieri693746 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesOscillospiraceaeOscillibacter
ProteomesiUP000005219: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

G4KXA3-1 [UniParc]FASTAAdd to Basket

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MAQLYFKYGA MGSSKTANAL MTRFNYEERG QQTLLVKPRL DTRDGDHMVY    50
SRIGLKHSCI YFDEMRRINP MELQQNACII VDEAQFLTKE EVDYLVSLVD 100
DCGIPVICYG LRADFKGDLF PGSEELLVMA DKIEEVKTIC WCGKKATFNA 150
RFDREGHVLK EGAQVVLGAN DQYIGLCRKH WRDGNLGPDF KAVQP 195
Length:195
Mass (Da):22,214
Last modified:December 14, 2011 - v1
Checksum:i8259F50A2045F908
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012044 Genomic DNA. Translation: BAL00912.1.
RefSeqiYP_004883417.1. NC_016048.1.

Genome annotation databases

EnsemblBacteriaiBAL00912; BAL00912; OBV_37130.
GeneIDi11235341.
KEGGiova:OBV_37130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP012044 Genomic DNA. Translation: BAL00912.1 .
RefSeqi YP_004883417.1. NC_016048.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAL00912 ; BAL00912 ; OBV_37130 .
GeneIDi 11235341.
KEGGi ova:OBV_37130.

Phylogenomic databases

KOi K00857.

Enzyme and pathway databases

BioCyci OVAL693746:GJWX-3769-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Whole genome sequence of Oscillibacter valericigenes Sjm18-20."
    Katano Y., Fujinami S., Kawakoshi A., Ohji S., Nakazawa H., Ankai A., Oguchi A., Fukui S., Terui Y., Harada T., Takahashi M., Suzuki K., Fujita N.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 18026 / NBRC 101213 / Sjm18-20.

Entry informationi

Entry nameiG4KXA3_OSCVS
AccessioniPrimary (citable) accession number: G4KXA3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: June 11, 2014
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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