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G4KVB7

- G4KVB7_OSCVS

UniProt

G4KVB7 - G4KVB7_OSCVS

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Protein

Alanine racemase

Gene

alr

Organism
Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei66 – 661Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei160 – 1601SubstrateUniRule annotation
Active sitei293 – 2931Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei342 – 3421Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciOVAL693746:GJWX-967-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:OBV_09480Imported
OrganismiOscillibacter valericigenes (strain DSM 18026 / NBRC 101213 / Sjm18-20)Imported
Taxonomic identifieri693746 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesOscillospiraceaeOscillibacter
ProteomesiUP000005219: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei66 – 661N6-(pyridoxal phosphate)lysineUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG4KVB7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

KOiK18348.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

G4KVB7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFRITAPWFR SRPVLLKGRK RMPDKREPAF CRGRAWIELD QKALRHNVGV
60 70 80 90 100
LRKLLPDGCE LMPAVKTNAY GHGAVLISRE LNRLGVNAFC VATVQEGAEL
110 120 130 140 150
RNNDITGTIL VLGYTHPKDF LLLRRYHLTQ TVLDLSYAKI LDRYGKKISV
160 170 180 190 200
HVKIDTGMRR LGERSEKIEE ISKIFECRNL NIEGIFTHLC VADENSSESV
210 220 230 240 250
AFTHAQAKAF YDVVAELHQR GFICPKKHIV SSDGLLYYPE LAENYARVGI
260 270 280 290 300
ALYGVLSTRA DTERCGISLE PVLSIKARIA LVKDLFQGEA AGYGLQFVAS
310 320 330 340 350
QDSRIAVVAI GYGDGIPRSL SCGVGSVLIQ GIKAPIVGRI CMDQMLVDIS
360 370 380 390 400
NIPNVKAGDV AVIIGQSGDE KITACDLAEQ DGTISNEILS RLGERLERQF

VGKKEF
Length:406
Mass (Da):44,958
Last modified:December 14, 2011 - v1
Checksum:i385ECD3435455264
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012044 Genomic DNA. Translation: BAK98146.1.
RefSeqiWP_014116834.1. NC_016048.1.
YP_004880652.1. NC_016048.1.

Genome annotation databases

EnsemblBacteriaiBAK98146; BAK98146; OBV_09480.
GeneIDi11233629.
KEGGiova:OBV_09480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP012044 Genomic DNA. Translation: BAK98146.1 .
RefSeqi WP_014116834.1. NC_016048.1.
YP_004880652.1. NC_016048.1.

3D structure databases

ProteinModelPortali G4KVB7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAK98146 ; BAK98146 ; OBV_09480 .
GeneIDi 11233629.
KEGGi ova:OBV_09480.

Phylogenomic databases

KOi K18348.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci OVAL693746:GJWX-967-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Whole genome sequence of Oscillibacter valericigenes Sjm18-20."
    Katano Y., Fujinami S., Kawakoshi A., Ohji S., Nakazawa H., Ankai A., Oguchi A., Fukui S., Terui Y., Harada T., Takahashi M., Suzuki K., Fujita N.
    Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 18026 / NBRC 101213 / Sjm18-20Imported.

Entry informationi

Entry nameiG4KVB7_OSCVS
AccessioniPrimary (citable) accession number: G4KVB7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: November 26, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3