Skip Header

Contribute Send feedback
Read comments (?) or add your own

G4KN08 (G4KN08_RICJY) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Leucine--tRNA ligase HAMAP-Rule MF_00049
EC=6.1.1.4 HAMAP-Rule MF_00049
Alternative name(s):
Leucyl-tRNA synthetase HAMAP-Rule MF_00049
Gene names
Name:leuS HAMAP-Rule MF_00049 EMBL BAK96666.1
Ordered Locus Names:RJP_0452 EMBL BAK96666.1
OrganismRickettsia japonica (strain ATCC VR-1363 / YH) [Complete proteome] [HAMAP]
Taxonomic identifier652620 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Rickettsiaceae › Rickettsieae › Rickettsia › spotted fever group ›

Protein attributes

Sequence length835 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu). HAMAP-Rule MF_00049

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00049.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489 HAMAP-Rule MF_00049

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif36 – 4611"HIGH" region By similarity HAMAP-Rule MF_00049
Motif602 – 6065"KMSKS" region By similarity HAMAP-Rule MF_00049

Sites

Binding site6051ATP By similarity HAMAP-Rule MF_00049

Sequences

Sequence LengthMass (Da)Tools
G4KN08 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 47AE42CBCD91B979

FASTA83596,646
        10         20         30         40         50         60 
MNQIEQKWQY IWQEEKAFEV SNASSKPKYY VLEMLPYPSG KIHVGHVRNY SIGDVIARFM 

        70         80         90        100        110        120 
TMQGFNVLHP MGWDAFGLPA ENAAIKNNSH PKKWTYSNIE NMKKQLKSMG FSYDWSREIN 

       130        140        150        160        170        180 
SCDPEYYKHE QKFFLELYER NLAYQKESFV NWDPVDNTVL ANEQVVDGRG WRSGAIVAKR 

       190        200        210        220        230        240 
YLKQWFLKIT DYAEELLNEI QNLKEWPEAV RSMQEKWIGK SIGANFHFKI KDNEETTIEV 

       250        260        270        280        290        300 
FSTKPETIFG ASFIGIAFNH PIIERLVSKT PEILAFITKC SHITRSSELE KAEKEGVFTG 

       310        320        330        340        350        360 
LFVTHPFDSN IVLPVIITNF VLMDYGTGAI FGCPAHDERD HELAVKMNLS IKQVIKADMD 

       370        380        390        400        410        420 
VQKTAYTEDG ILINSDFLNG LTSNEAKQEV IGEFEKLGIG KRSVNYRLKD WGISRQRFWG 

       430        440        450        460        470        480 
CPIPMIHCET CGIVSVPYKD LPVTLPDDVN FDGHGNPLDH HPSWKHVNCP KCDKPAVRET 

       490        500        510        520        530        540 
DTFDTFFESS WYFTRYCNSN ATEMTDKKAC DYWLPVDKYI GGIEHAVMHL LYARFFTKVM 

       550        560        570        580        590        600 
NEQNYVSVRE PFKGLFTQGM VLHATYKDEH NNWLYPEEVV KKGNEFFHKE SNNRVVQGRI 

       610        620        630        640        650        660 
EKMSKSKKNL IDLETMQEQY GADAIRLFVL SDSPPEKDLE WSTSGIEGCS RFINKLEYMF 

       670        680        690        700        710        720 
KAIDSLKDDV NSEINKELNR LVHFTIKHVA EDIKHFALNR AIARMRELSN VISAEISKDK 

       730        740        750        760        770        780 
IDVKTVRHGF NVLVQLLNPF IPHITEEIWQ KLGNKERLYN LSFPAFDESM LELDTYIIAV 

       790        800        810        820        830 
QVNGKLRDTY EFKTSVSEDE IKQVTVSLPK VQKFLEGKEP KKIILVPRKI VNILV

« Hide

References

[1]"Complete genome sequence of Rickettsia japonica YH strain."
Matsutani M., Ogawa M., Kishimoto T., Azuma Y., Hattori M., Hanaoka N., Takaoka N., Hirakawa H., Kuhara S., Shirai M.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC VR-1363 / YH.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP011533 Genomic DNA. Translation: BAK96666.1.
RefSeqYP_004884805.1. NC_016050.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK96666; BAK96666; RJP_0452.
GeneID11232190.
KEGGrja:RJP_0452.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01869.

Enzyme and pathway databases

BioCycRJAP652620:GJUC-452-MONOMER.

Family and domain databases

Gene3D3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPMF_00049_B. Leu_tRNA_synth_B.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase_bac/mito.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSPR00985. TRNASYNTHLEU.
SUPFAMSSF47323. tRNAsyn_1a_bind. 1 hit.
SSF50677. ValRS_IleRS_edit. 1 hit.
TIGRFAMsTIGR00396. leuS_bact. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4KN08_RICJY
AccessionPrimary (citable) accession number: G4KN08
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info