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G4FFF4

- G4FFF4_THEMA

UniProt

G4FFF4 - G4FFF4_THEMA

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Protein
Submitted name:

CTP:Inositol-1-phosphate cytidylyltransferase / Phospho-di-inositol-1-phosphate synthase

Gene

THEMA_07220

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei122 – 1221Phosphate 1Imported
Metal bindingi131 – 1311SodiumImported
Binding sitei192 – 1921Phosphate 2Imported
Binding sitei193 – 1931Phosphate 3Imported
Binding sitei197 – 1971Phosphate 3Imported
Binding sitei207 – 2071Phosphate 1; via carbonyl oxygenImported
Metal bindingi210 – 2101SodiumImported
Metal bindingi211 – 2111Sodium; via carbonyl oxygenImported
Metal bindingi213 – 2131Sodium; via carbonyl oxygenImported

GO - Molecular functioni

  1. nucleotidyltransferase activity Source: UniProtKB-KW

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
CTP:Inositol-1-phosphate cytidylyltransferase / Phospho-di-inositol-1-phosphate synthaseImported (EC:2.7.8.-Imported)
Submitted name:
Nucleotidyl transferaseImported
Gene namesi
ORF Names:THEMA_07220Imported, Tmari_1425Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4JD0X-ray1.80A1-241[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni157 – 1582Phosphate 2 bindingImported

Family and domain databases

Gene3Di3.90.550.10. 1 hit.
InterProiIPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

G4FFF4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MREAIVLASG AGKRLRSVTG DVPKVFYRFD GCELVKYPMI SLMKNGVERF
60 70 80 90 100
VLVVSEGYRD LGEKVLNDLG VEGIVVENKK VELGNAYSFF LSEPYVESEK
110 120 130 140 150
FFLSCGDSLF PPEALKSAFS EDEFHIKLGV SKRSDLIDPE EASKVLVNED
160 170 180 190 200
RIVKIGKRID EYNYFDTGVF VMTKKVYSLK ESFSWTEEIS LYHVLQKAVD
210 220 230 240
TGMIVKVFDF GNALWTEIDS PEDLNEKVYE LMKKIKEGVA C
Length:241
Mass (Da):27,323
Last modified:December 14, 2011 - v1
Checksum:i8153E6A8592ECF10
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP004077 Genomic DNA. Translation: AGL50349.1.
CP007013 Genomic DNA. Translation: AHD18687.1.
RefSeqiYP_007977774.1. NC_021214.1.
YP_008991491.1. NC_023151.1.

Genome annotation databases

EnsemblBacteriaiAGL50349; AGL50349; Tmari_1425.
GeneIDi18093291.
KEGGitmi:THEMA_07220.
tmm:Tmari_1425.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP004077 Genomic DNA. Translation: AGL50349.1 .
CP007013 Genomic DNA. Translation: AHD18687.1 .
RefSeqi YP_007977774.1. NC_021214.1.
YP_008991491.1. NC_023151.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4JD0 X-ray 1.80 A 1-241 [» ]
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AGL50349 ; AGL50349 ; Tmari_1425 .
GeneIDi 18093291.
KEGGi tmi:THEMA_07220.
tmm:Tmari_1425.

Family and domain databases

Gene3Di 3.90.550.10. 1 hit.
InterProi IPR005835. NTP_transferase.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view ]
Pfami PF00483. NTP_transferase. 1 hit.
[Graphical view ]
SUPFAMi SSF53448. SSF53448. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Structure of the inositol-1-phosphate cytidylyltransferase from Thermotoga maritima."
    Kurnasov O.V., Luk H.J., Roberts M.F., Stec B.
    Acta Crystallogr. D 69:1808-1817(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
  2. "The genome organization of Thermotoga maritima reflects its lifestyle."
    Latif H., Lerman J.A., Portnoy V.A., Tarasova Y., Nagarajan H., Schrimpe-Rutledge A.C., Smith R.D., Adkins J.N., Lee D.H., Qiu Y., Zengler K.
    PLoS Genet. 9:E1003485-E1003485(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099Imported and MSB8Imported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MSB8Imported.

Entry informationi

Entry nameiG4FFF4_THEMA
AccessioniPrimary (citable) accession number: G4FFF4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: October 29, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3