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G4FEQ0 (G4FEQ0_THEMA) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ornithine carbamoyltransferase HAMAP-Rule MF_01109

Short name=OTCase HAMAP-Rule MF_01109
EC=2.1.3.3 HAMAP-Rule MF_01109
Gene names
Name:argF HAMAP-Rule MF_01109
ORF Names:ThemaDRAFT_0214 EMBL EHA60971.1
OrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) EMBL EHA60971.1
Taxonomic identifier243274 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length313 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. HAMAP-Rule MF_01109 SAAS SAAS002292

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3. HAMAP-Rule MF_01109

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01109 SAAS SAAS002292.

Sequence similarities

Belongs to the ATCase/OTCase family. HAMAP-Rule MF_01109 RuleBase RU003634

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EHA60971.1

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region57 – 615Carbamoyl phosphate binding By similarity HAMAP-Rule MF_01109
Region271 – 2744Ornithine binding By similarity HAMAP-Rule MF_01109

Sites

Binding site1081Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
Binding site1351Carbamoyl phosphate By similarity HAMAP-Rule MF_01109
Site321Important for structural integrity By similarity HAMAP-Rule MF_01109
Site1481Important for structural integrity By similarity HAMAP-Rule MF_01109

Sequences

Sequence LengthMass (Da)Tools
G4FEQ0 [UniParc].

Last modified December 14, 2011. Version 1.
Checksum: 0C813CAC3B8C6F8D

FASTA31335,362
        10         20         30         40         50         60 
MSVNLKGRSL LTLLDFSPEE IRYLLDISKQ VKMENRSKLR TERFKGMTLA MIFEKRSTRT 

        70         80         90        100        110        120 
RLAFETAFAE EGGHPIFLSP NDIHLGAKES LEDTARVLGR MVDAIMFRGY KQETVEKLAE 

       130        140        150        160        170        180 
YSGVPVYNGL TDEFHPTQAL ADLMTIEENF GRLKGVKVVF MGDTRNNVAT SLMIACAKMG 

       190        200        210        220        230        240 
MNFVACGPEE LKPRSDVFKR CQEIVKETDG SVSFTSNLEE ALAGADVVYT DVWASMGEED 

       250        260        270        280        290        300 
KEKERMALLK PYQVNERVME MTGKSETIFM HCLPAVKGQE VTYEVIEGKQ SRVWDEAENR 

       310 
KHTIKAVMIA TLL 

« Hide

References

[1]"The draft genome of Thermotoga maritima MSB8."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Land M.L., Hauser L., Boucher N., Noll K., Woyke T.
Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MSB8 EMBL EHA60971.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AGIJ01000001 Genomic DNA. Translation: EHA60971.1.
RefSeqNP_228903.1. NC_000853.1.

3D structure databases

ProteinModelPortalG4FEQ0.
SMRG4FEQ0. Positions 1-313.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEHA60971; EHA60971; ThemaDRAFT_0214.
GeneID898668.
KEGGtma:TM1097.

Phylogenomic databases

KOK00611.
OMAFMTIKEH.

Enzyme and pathway databases

UniPathwayUPA00068; UER00112.

Family and domain databases

HAMAPMF_01109. OTCase.
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. Orn_carbamltrans.
[Graphical view]
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMSSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMsTIGR00658. orni_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG4FEQ0_THEMA
AccessionPrimary (citable) accession number: G4FEQ0
Entry history
Integrated into UniProtKB/TrEMBL: December 14, 2011
Last sequence update: December 14, 2011
Last modified: April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)