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G3XDD8

- LYG_DRONO

UniProt

G3XDD8 - LYG_DRONO

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Protein

Lysozyme G

Gene
N/A
Organism
Dromaius novaehollandiae (Emu)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Has bacteriolytic activity against M.luteus.1 Publication

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei92 – 921By similarity
Active sitei105 – 1051By similarity

GO - Molecular functioni

  1. lysozyme activity Source: UniProtKB-EC

GO - Biological processi

  1. cell wall macromolecule catabolic process Source: InterPro
  2. cytolysis Source: UniProtKB-KW
  3. defense response to bacterium Source: UniProtKB-KW
  4. peptidoglycan catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Lysozyme GImported (EC:3.2.1.17By similarity)
Alternative name(s):
1,4-beta-N-acetylmuramidaseBy similarity
OrganismiDromaius novaehollandiae (Emu)
Taxonomic identifieri8790 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesPalaeognathaeCasuariiformesDromaiidaeDromaius

Subcellular locationi

Secreted By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 204185Lysozyme GSequence AnalysisPRO_5000795990Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi23 ↔ 79By similarity
Disulfide bondi37 ↔ 48By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliG3XDD8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 23 family.Sequence Analysis

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR002152. Glyco_hydro_23.
IPR023346. Lysozyme-like_dom.
IPR008258. TGlycosylase-like_SLT.
[Graphical view]
PfamiPF01464. SLT. 1 hit.
[Graphical view]
PIRSFiPIRSF001065. Lysozyme_g. 1 hit.
PRINTSiPR00749. LYSOZYMEG.
SUPFAMiSSF53955. SSF53955. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

G3XDD8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHLMLVLLGL AALLGTSQSQ TGCYGVVNRI DTTGASCETA KPEKLNYCGV
60 70 80 90 100
AASRMIAERD LRSMDRYKTL IKKVGQKLCV DPAVIAGIIS RESHAGKALK
110 120 130 140 150
NGWGDNGNGF GLMQVDKRSH TPVGEWNGER HLTQGTEILI SMIKKIQKKF
160 170 180 190 200
PRWTKEQQLK GGISAYNAGS GNVRSYERMD IGTTHNDYAN DVVARAQYYK

QHGY
Length:204
Mass (Da):22,493
Last modified:December 14, 2011 - v1
Checksum:i4061327BB92C820C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB451700 mRNA. Translation: BAL03618.1.
AB462632 Genomic DNA. Translation: BAL03619.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB451700 mRNA. Translation: BAL03618.1 .
AB462632 Genomic DNA. Translation: BAL03619.1 .

3D structure databases

ProteinModelPortali G3XDD8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR002152. Glyco_hydro_23.
IPR023346. Lysozyme-like_dom.
IPR008258. TGlycosylase-like_SLT.
[Graphical view ]
Pfami PF01464. SLT. 1 hit.
[Graphical view ]
PIRSFi PIRSF001065. Lysozyme_g. 1 hit.
PRINTSi PR00749. LYSOZYMEG.
SUPFAMi SSF53955. SSF53955. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white."
    Maehashi K., Matano M., Irisawa T., Uchino M., Kashiwagi Y., Watanabe T.
    Gene 492:244-249(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], FUNCTION, TISSUE SPECIFICITY.
    Tissue: OvaryImported and OviductImported.

Entry informationi

Entry nameiLYG_DRONO
AccessioniPrimary (citable) accession number: G3XDD8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: December 14, 2011
Last modified: October 29, 2014
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3