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Protein
Submitted name:

Caspase recruitment domain family, member 4, isoform CRA_c

Gene

NOD1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase recruitment domain family, member 4, isoform CRA_cImported
Submitted name:
Nucleotide-binding oligomerization domain-containing protein 1Imported
Gene namesi
Name:NOD1Imported
Synonyms:CARD4Imported
ORF Names:hCG_39138Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:16390. NOD1.

PTM / Processingi

Proteomic databases

PeptideAtlasiG3XAL1.

Expressioni

Gene expression databases

BgeeiENSG00000106100.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000222823.

Structurei

3D structure databases

SMRiG3XAL1. Positions 9-106, 193-218, 678-769.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 9278CARDInterPro annotationAdd
BLAST
Domaini196 – 531336NACHTInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains NACHT domain.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4308. Eukaryota.
ENOG410ZBX3. LUCA.
GeneTreeiENSGT00840000129782.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR001315. CARD.
IPR011029. DEATH-like_dom.
IPR032675. L_dom-like.
IPR007111. NACHT_NTPase.
[Graphical view]
PfamiPF00619. CARD. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS50837. NACHT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3XAL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEQGHSEME IIPSESHPHI QLLKSNRELL VTHIRNTQCL VDNLLKNDYF
60 70 80 90 100
SAEDAEIVCA CPTQPDKVRK ILDLVQSKGE EVSEFFLYLL QQLADAYVDL
110 120 130 140 150
RPWLLEIGFS PSLLTQSKVV VNTDPVSRYT QQLRHHLGRD SKFVLCYAQK
160 170 180 190 200
EELLLEEIYM DTIMELVGFS NESLGSLNSL ACLLDHTTGI LNEQGETIFI
210 220 230 240 250
LGDAGVGKSM LLQRLQSLWA TGRLDAGVKF FFHFRCRMFS CFKESDRLCL
260 270 280 290 300
QDLLFKHYCY PERDPEEVFA FLLRFPHVAL FTFDGLDELH SDLDLSRVPD
310 320 330 340 350
SSCPWEPAHP LVLLANLLSG KLLKGASKLL TARTGIEVPR QFLRKKVLLR
360 370 380 390 400
GFSPSHLRAY ARRMFPERAL QDRLLSQLEA NPNLCSLCSV PLFCWIIFRC
410 420 430 440 450
FQHFRAAFEG SPQLPDCTMT LTDVFLLVTE VHLNRMQPSS LVQRNTRSPV
460 470 480 490 500
ETLHAGRDTL CSLGQVAHRG MEKSLFVFTQ EEVQASGLQE RDMQLGFLRA
510 520 530 540 550
LPELGPGGDQ QSYEFFHLTL QAFFTAFFLV LDDRVGTQEL LRFFQEWMPP
560 570 580 590 600
AGAATTSCYP PFLPFQCLQG SGPAREDLFK NKDHFQFTNL FLCGLLSKAK
610 620 630 640 650
QKLLRHLVPA AALRRKRKAL WAHLFSSLRG YLKSLPRVQV ESFNQVQAMP
660 670 680 690 700
TFIWMLRCIY ETQSQKVGQL AARGICANYL KLTYCNACSA DCSALSFVLH
710 720 730 740 750
HFPKRLALDL DNNNLNDYGV RELQPCFSRL TVLRLSVNQI TDGGVKVLSE
760 770
ELTKYKIVTY LGLWKSVDTI CFKKQGLLK
Length:779
Mass (Da):88,842
Last modified:November 16, 2011 - v1
Checksum:i06801B8E4730A1D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005154 Genomic DNA. No translation available.
AC006027 Genomic DNA. No translation available.
CH471073 Genomic DNA. Translation: EAW93948.1.
RefSeqiXP_011513390.1. XM_011515088.2.
UniGeneiHs.405153.
Hs.738731.

Genome annotation databases

EnsembliENST00000434755; ENSP00000416946; ENSG00000106100.
GeneIDi10392.
UCSCiuc064cml.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005154 Genomic DNA. No translation available.
AC006027 Genomic DNA. No translation available.
CH471073 Genomic DNA. Translation: EAW93948.1.
RefSeqiXP_011513390.1. XM_011515088.2.
UniGeneiHs.405153.
Hs.738731.

3D structure databases

SMRiG3XAL1. Positions 9-106, 193-218, 678-769.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000222823.

Proteomic databases

PeptideAtlasiG3XAL1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000434755; ENSP00000416946; ENSG00000106100.
GeneIDi10392.
UCSCiuc064cml.1. human.

Organism-specific databases

CTDi10392.
HGNCiHGNC:16390. NOD1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4308. Eukaryota.
ENOG410ZBX3. LUCA.
GeneTreeiENSGT00840000129782.

Miscellaneous databases

ChiTaRSiNOD1. human.
GenomeRNAii10392.

Gene expression databases

BgeeiENSG00000106100.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
3.80.10.10. 1 hit.
InterProiIPR001315. CARD.
IPR011029. DEATH-like_dom.
IPR032675. L_dom-like.
IPR007111. NACHT_NTPase.
[Graphical view]
PfamiPF00619. CARD. 1 hit.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50209. CARD. 1 hit.
PS50837. NACHT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG3XAL1_HUMAN
AccessioniPrimary (citable) accession number: G3XAL1
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 7, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.