UniProtKB - G3XAL1 (G3XAL1_HUMAN)
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Protein
Submitted name:
Caspase recruitment domain family, member 4, isoform CRA_c
Gene
NOD1
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- regulation of apoptotic process Source: InterPro
Keywordsi
Ligand | ATP-bindingSAAS annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Caspase recruitment domain family, member 4, isoform CRA_cImportedSubmitted name: Nucleotide-binding oligomerization domain-containing protein 1Imported |
Gene namesi | ORF Names:hCG_39138Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000106100.10. |
HGNCi | HGNC:16390. NOD1. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 15 – 92 | CARDInterPro annotationAdd BLAST | 78 | |
Domaini | 196 – 531 | NACHTInterPro annotationAdd BLAST | 336 |
Keywords - Domaini
RepeatSAAS annotationPhylogenomic databases
eggNOGi | KOG4308. Eukaryota. ENOG410ZBX3. LUCA. |
GeneTreei | ENSGT00860000133673. |
Family and domain databases
Gene3Di | 3.80.10.10. 1 hit. |
InterProi | View protein in InterPro IPR001315. CARD. IPR011029. DEATH-like_dom_sf. IPR032675. LRR_dom_sf. IPR007111. NACHT_NTPase. |
Pfami | View protein in Pfam PF00619. CARD. 1 hit. |
SUPFAMi | SSF47986. SSF47986. 1 hit. |
PROSITEi | View protein in PROSITE PS50209. CARD. 1 hit. PS50837. NACHT. 1 hit. |
i Sequence
Sequence statusi: Complete.
G3XAL1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEEQGHSEME IIPSESHPHI QLLKSNRELL VTHIRNTQCL VDNLLKNDYF
60 70 80 90 100
SAEDAEIVCA CPTQPDKVRK ILDLVQSKGE EVSEFFLYLL QQLADAYVDL
110 120 130 140 150
RPWLLEIGFS PSLLTQSKVV VNTDPVSRYT QQLRHHLGRD SKFVLCYAQK
160 170 180 190 200
EELLLEEIYM DTIMELVGFS NESLGSLNSL ACLLDHTTGI LNEQGETIFI
210 220 230 240 250
LGDAGVGKSM LLQRLQSLWA TGRLDAGVKF FFHFRCRMFS CFKESDRLCL
260 270 280 290 300
QDLLFKHYCY PERDPEEVFA FLLRFPHVAL FTFDGLDELH SDLDLSRVPD
310 320 330 340 350
SSCPWEPAHP LVLLANLLSG KLLKGASKLL TARTGIEVPR QFLRKKVLLR
360 370 380 390 400
GFSPSHLRAY ARRMFPERAL QDRLLSQLEA NPNLCSLCSV PLFCWIIFRC
410 420 430 440 450
FQHFRAAFEG SPQLPDCTMT LTDVFLLVTE VHLNRMQPSS LVQRNTRSPV
460 470 480 490 500
ETLHAGRDTL CSLGQVAHRG MEKSLFVFTQ EEVQASGLQE RDMQLGFLRA
510 520 530 540 550
LPELGPGGDQ QSYEFFHLTL QAFFTAFFLV LDDRVGTQEL LRFFQEWMPP
560 570 580 590 600
AGAATTSCYP PFLPFQCLQG SGPAREDLFK NKDHFQFTNL FLCGLLSKAK
610 620 630 640 650
QKLLRHLVPA AALRRKRKAL WAHLFSSLRG YLKSLPRVQV ESFNQVQAMP
660 670 680 690 700
TFIWMLRCIY ETQSQKVGQL AARGICANYL KLTYCNACSA DCSALSFVLH
710 720 730 740 750
HFPKRLALDL DNNNLNDYGV RELQPCFSRL TVLRLSVNQI TDGGVKVLSE
760 770
ELTKYKIVTY LGLWKSVDTI CFKKQGLLK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005154 Genomic DNA. No translation available. AC006027 Genomic DNA. No translation available. CH471073 Genomic DNA. Translation: EAW93948.1. |
RefSeqi | XP_011513390.1. XM_011515088.2. |
UniGenei | Hs.405153. Hs.738731. |
Genome annotation databases
Ensembli | ENST00000434755; ENSP00000416946; ENSG00000106100. |
GeneIDi | 10392. |
UCSCi | uc064cml.1. human. |
Similar proteinsi
Entry informationi
Entry namei | G3XAL1_HUMAN | |
Accessioni | G3XAL1Primary (citable) accession number: G3XAL1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 16, 2011 |
Last sequence update: | November 16, 2011 | |
Last modified: | February 28, 2018 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |