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Protein
Submitted name:

Ubiquitin conjugation factor E4 A

Gene

Ube4a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin conjugation factor E4 AImported
Submitted name:
Ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)Imported
Gene namesi
Name:Ube4aImported
ORF Names:mCG_50277Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2154580. Ube4a.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PeptideAtlasiG3X9Y5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1006 – 108075U-boxInterPro annotationAdd
BLAST

Phylogenomic databases

GeneTreeiENSGT00390000009300.
OMAiHFEDVTE.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR019474. Ub_conjug_fac_E4_core.
IPR003613. Ubox_domain.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF04564. U-box. 1 hit.
PF10408. Ufd2P_core. 1 hit.
[Graphical view]
SMARTiSM00504. Ubox. 1 hit.
[Graphical view]
PROSITEiPS51698. U_BOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3X9Y5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDQENNNNI SSNPFAALFG SLADAKQFAA IQKEQLKQQS GSVFGSEEEA
60 70 80 90 100
LCNSLHVPAD ELPASPDDSD NSVSESLDEF DYSVSEISRS FRTHQEMCEQ
110 120 130 140 150
LNINHMIQRI FLITLDNSDP SLKSGNGIPS RCVYLEEMAV ELEDQDWLDM
160 170 180 190 200
SNVEQAIFAR LLLQDPGNHL ISMTSSTTLN LSADRDAGER HIFCYLYSCF
210 220 230 240 250
QRAKEEITKV PENLLPFAVQ CRNLTVSNTR TVLLTPEIYV DQNIHEQLVD
260 270 280 290 300
LMLEAIQGAH FEDVTEFLEE VIEALLLDEE VRTFPEVMIP VFDILLSRIK
310 320 330 340 350
DLELCQILLY AYLDILLYFT RQKDMAKVFL EYIQPKDPSN GQMYQKTLLG
360 370 380 390 400
VILNISCLLK TPGVVENHGF FLNPSRSSPQ EIKVQEANIH QFMAQFHEKI
410 420 430 440 450
YQMLKNLLQL SPETKHCILF WLGNCLHANA GRTKIWANQM PEIFFQMYAS
460 470 480 490 500
DAFFLNLGAA LLKLCQPFCK PRSSRLLTFN PTYCVLKDLN DEERKIKSVH
510 520 530 540 550
MRGLDKETCL IPAVQEPTFP QSYNLVTENL ALTEYTLYLG FHRLHDQMVK
560 570 580 590 600
INQNLHRLQV AWRDAQQSSS PAADNLREQF ERLMTIYLST KTAMTEPQML
610 620 630 640 650
QNCLNLQVSM AVLLVQLAIG NEGSQPIELS FPLPDGYSSL AYVPEFFADN
660 670 680 690 700
LGDFLIFLRR FAEDILETSA DSLEHVLHFI TIFTGSIERM KNPHLRAKLA
710 720 730 740 750
EVLEAVMPHL DQTPSPLVSS VFHRKRVFCN FPYAPQLAEA LIKVFVDIEF
760 770 780 790 800
TGDPHQFEQK FNYRRPMYPI LRYMWGTDCY RESIKDLADY ASKNLEAMNP
810 820 830 840 850
PLFLRFLNLL MNDAIFLLDE AIQYLSKIKI QQIEKDRGEW ESLTPEARRE
860 870 880 890 900
KEAGLQMFGQ LARFHNIMSN ETIGTLSFLT SEIKSLFVHP FLAERIISML
910 920 930 940 950
NYFLQHLVGP KMGALKVKDF SEFDFKPQQL VSDICTIYLN LGDEENFCAT
960 970 980 990 1000
VPKDGRSYSP TLFAQTVRVL KKINKPGNMI VAFSNLAERI KSLADLQQQE
1010 1020 1030 1040 1050
EETYADACDE FLDPIMSTLM SDPVVLPSSR VTVDRSTIAR HLLSDQTDPF
1060 1070 1080
NRSPLTMDQI RPNTELKEKI QRWLAERKQQ KEQPE
Length:1,085
Mass (Da):124,463
Last modified:November 16, 2011 - v1
Checksum:i8AE9161CB7B6E388
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC061963 Genomic DNA. No translation available.
CH466522 Genomic DNA. Translation: EDL25625.1.
RefSeqiXP_006510064.1. XM_006510001.2.
XP_006510065.1. XM_006510002.2.
XP_011240696.1. XM_011242394.1.
XP_011240697.1. XM_011242395.1.
UniGeneiMm.215069.
Mm.421524.

Genome annotation databases

EnsembliENSMUST00000117549; ENSMUSP00000112632; ENSMUSG00000059890.
GeneIDi140630.
UCSCiuc009pev.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC061963 Genomic DNA. No translation available.
CH466522 Genomic DNA. Translation: EDL25625.1.
RefSeqiXP_006510064.1. XM_006510001.2.
XP_006510065.1. XM_006510002.2.
XP_011240696.1. XM_011242394.1.
XP_011240697.1. XM_011242395.1.
UniGeneiMm.215069.
Mm.421524.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiG3X9Y5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000117549; ENSMUSP00000112632; ENSMUSG00000059890.
GeneIDi140630.
UCSCiuc009pev.2. mouse.

Organism-specific databases

CTDi9354.
MGIiMGI:2154580. Ube4a.

Phylogenomic databases

GeneTreeiENSGT00390000009300.
OMAiHFEDVTE.

Miscellaneous databases

ChiTaRSiUbe4a. mouse.
SOURCEiSearch...

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR019474. Ub_conjug_fac_E4_core.
IPR003613. Ubox_domain.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF04564. U-box. 1 hit.
PF10408. Ufd2P_core. 1 hit.
[Graphical view]
SMARTiSM00504. Ubox. 1 hit.
[Graphical view]
PROSITEiPS51698. U_BOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3X9Y5_MOUSE
AccessioniPrimary (citable) accession number: G3X9Y5
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: July 6, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.