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Protein

Guanine nucleotide-binding protein subunit gamma

Gene

Gng7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducerUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Guanine nucleotide-binding protein subunit gammaUniRule annotation
Gene namesi
Name:Gng7Imported
ORF Names:mCG_12135Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:95787 Gng7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Keywords - PTMi

LipoproteinUniRule annotation

Proteomic databases

MaxQBiG3X9Q2
PeptideAtlasiG3X9Q2

Expressioni

Gene expression databases

BgeeiENSMUSG00000048240

Interactioni

Subunit structurei

G proteins are composed of 3 units; alpha, beta and gamma.UniRule annotation

Structurei

3D structure databases

SMRiG3X9Q2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 69G protein gammaInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the G protein gamma family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4119 Eukaryota
ENOG41122JF LUCA
GeneTreeiENSGT00760000119218
KOiK04543
OMAiSELMNYC
OrthoDBiEOG091G17J0
TreeFamiTF319909

Family and domain databases

CDDicd00068 GGL, 1 hit
Gene3Di4.10.260.10, 1 hit
InterProiView protein in InterPro
IPR015898 G-protein_gamma-like_dom
IPR036284 GGL_sf
IPR001770 Gprotein-gamma
PANTHERiPTHR13809 PTHR13809, 1 hit
PfamiView protein in Pfam
PF00631 G-gamma, 1 hit
PRINTSiPR00321 GPROTEING
SMARTiView protein in SMART
SM00224 GGL, 1 hit
SUPFAMiSSF48670 SSF48670, 1 hit
PROSITEiView protein in PROSITE
PS50058 G_PROTEIN_GAMMA, 1 hit

Sequencei

Sequence statusi: Complete.

G3X9Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSGTNNVAQ ARKLVEQLRI EAGIERIKVS KASSDLMGYC EQHARNDPLL
60
VGVPASENPF KDKKPCIIL
Length:69
Mass (Da):7,611
Last modified:November 16, 2011 - v1
Checksum:iC93EC667C40C2C61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152500 Genomic DNA No translation available.
CH466553 Genomic DNA Translation: EDL31470.1
RefSeqiNP_001033744.1, NM_001038655.1
NP_034449.2, NM_010319.3
UniGeneiMm.222496

Genome annotation databases

EnsembliENSMUST00000092285; ENSMUSP00000089936; ENSMUSG00000048240
ENSMUST00000099462; ENSMUSP00000097061; ENSMUSG00000048240
GeneIDi14708
KEGGimmu:14708
UCSCiuc007gfm.1 mouse

Similar proteinsi

Entry informationi

Entry nameiG3X9Q2_MOUSE
AccessioniPrimary (citable) accession number: G3X9Q2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 25, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health