Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Guanine nucleotide binding protein (G protein), gamma 7 subunit

Gene

Gng7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.UniRule annotation

GO - Molecular functioni

  1. signal transducer activity Source: MGI

GO - Biological processi

  1. behavioral fear response Source: MGI
  2. G-protein coupled receptor signaling pathway Source: InterPro
  3. locomotory behavior Source: MGI
  4. receptor guanylyl cyclase signaling pathway Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

TransducerUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide binding protein (G protein), gamma 7 subunitImported
Submitted name:
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7Imported
Gene namesi
Name:Gng7Imported
ORF Names:mCG_12135Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:95787. Gng7.

Subcellular locationi

Cell membrane UniRule annotation; Lipid-anchor UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

  1. extracellular vesicular exosome Source: MGI
  2. heterotrimeric G-protein complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

PTM / Processingi

Keywords - PTMi

LipoproteinUniRule annotation

Proteomic databases

PRIDEiG3X9Q2.

Expressioni

Gene expression databases

BgeeiG3X9Q2.
ExpressionAtlasiG3X9Q2. baseline and differential.

Interactioni

Subunit structurei

G proteins are composed of 3 units; alpha, beta and gamma.UniRule annotation

Structurei

3D structure databases

SMRiG3X9Q2. Positions 10-59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G protein gamma family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119218.
KOiK04543.
OMAiSELMNYC.
TreeFamiTF319909.

Family and domain databases

Gene3Di4.10.260.10. 1 hit.
InterProiIPR015898. G-protein_gamma-like_dom.
IPR001770. Gprotein-gamma.
[Graphical view]
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiPF00631. G-gamma. 1 hit.
[Graphical view]
PRINTSiPR00321. GPROTEING.
SMARTiSM00224. GGL. 1 hit.
[Graphical view]
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiPS50058. G_PROTEIN_GAMMA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3X9Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMSGTNNVAQ ARKLVEQLRI EAGIERIKVS KASSDLMGYC EQHARNDPLL
60
VGVPASENPF KDKKPCIIL
Length:69
Mass (Da):7,611
Last modified:November 15, 2011 - v1
Checksum:iC93EC667C40C2C61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152500 Genomic DNA. No translation available.
CH466553 Genomic DNA. Translation: EDL31470.1.
RefSeqiNP_001033744.1. NM_001038655.1.
NP_034449.2. NM_010319.3.
XP_006513301.1. XM_006513238.2.
UniGeneiMm.222496.

Genome annotation databases

EnsembliENSMUST00000092285; ENSMUSP00000089936; ENSMUSG00000048240.
ENSMUST00000099462; ENSMUSP00000097061; ENSMUSG00000048240.
GeneIDi14708.
KEGGimmu:14708.
UCSCiuc007gfm.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC152500 Genomic DNA. No translation available.
CH466553 Genomic DNA. Translation: EDL31470.1.
RefSeqiNP_001033744.1. NM_001038655.1.
NP_034449.2. NM_010319.3.
XP_006513301.1. XM_006513238.2.
UniGeneiMm.222496.

3D structure databases

SMRiG3X9Q2. Positions 10-59.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiG3X9Q2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000092285; ENSMUSP00000089936; ENSMUSG00000048240.
ENSMUST00000099462; ENSMUSP00000097061; ENSMUSG00000048240.
GeneIDi14708.
KEGGimmu:14708.
UCSCiuc007gfm.1. mouse.

Organism-specific databases

CTDi2788.
MGIiMGI:95787. Gng7.

Phylogenomic databases

GeneTreeiENSGT00760000119218.
KOiK04543.
OMAiSELMNYC.
TreeFamiTF319909.

Miscellaneous databases

NextBioi286695.
SOURCEiSearch...

Gene expression databases

BgeeiG3X9Q2.
ExpressionAtlasiG3X9Q2. baseline and differential.

Family and domain databases

Gene3Di4.10.260.10. 1 hit.
InterProiIPR015898. G-protein_gamma-like_dom.
IPR001770. Gprotein-gamma.
[Graphical view]
PANTHERiPTHR13809. PTHR13809. 1 hit.
PfamiPF00631. G-gamma. 1 hit.
[Graphical view]
PRINTSiPR00321. GPROTEING.
SMARTiSM00224. GGL. 1 hit.
[Graphical view]
SUPFAMiSSF48670. SSF48670. 1 hit.
PROSITEiPS50058. G_PROTEIN_GAMMA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (AUG-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (JAN-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiG3X9Q2_MOUSE
AccessioniPrimary (citable) accession number: G3X9Q2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 15, 2011
Last sequence update: November 15, 2011
Last modified: March 31, 2015
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.