Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

G3X9H5 (G3X9H5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

Huntington disease gene homolog, isoform CRA_a EMBL EDL37467.1
Gene names
Name:Htt MGI 96067 Ensembl ENSMUSP00000078945
Synonyms:Hdh EMBL EDL37467.1
ORF Names:mCG_2547 EMBL EDL37467.1
OrganismMus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000078945
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length3120 AA.
Sequence statusComplete.
Protein existencePredicted

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processER to Golgi vesicle-mediated transport

Inferred from mutant phenotype PubMed 11092755. Source: MGI

Golgi organization

Inferred from electronic annotation. Source: Ensembl

L-glutamate import

Inferred from mutant phenotype PubMed 10932179. Source: MGI

anatomical structure morphogenesis

Inferred from mutant phenotype PubMed 16109169. Source: MGI

anterior/posterior pattern specification

Inferred from mutant phenotype PubMed 16109169. Source: MGI

apoptotic process

Inferred from mutant phenotype PubMed 7550343. Source: MGI

associative learning

Inferred from mutant phenotype PubMed 17284197. Source: MGI

axon cargo transport

Inferred from mutant phenotype PubMed 15340079. Source: MGI

brain development

Inferred from mutant phenotype PubMed 16978870. Source: MGI

cell aging

Inferred from mutant phenotype PubMed 16403806. Source: MGI

cell death

Inferred from mutant phenotype PubMed 22956852. Source: MGI

central nervous system development

Inferred from mutant phenotype PubMed 9398841. Source: MGI

citrulline metabolic process

Inferred from mutant phenotype PubMed 17213233. Source: MGI

determination of adult lifespan

Inferred from mutant phenotype PubMed 11062468PubMed 11152661. Source: MGI

dopamine receptor signaling pathway

Inferred from mutant phenotype PubMed 17715336. Source: MGI

embryo development

Inferred from mutant phenotype PubMed 16978870PubMed 9398841. Source: MGI

endoplasmic reticulum organization

Inferred from mutant phenotype PubMed 16256944. Source: MGI

endosomal transport

Inferred from mutant phenotype PubMed 11092755. Source: MGI

establishment of mitotic spindle orientation

Inferred from electronic annotation. Source: Ensembl

gastrulation

Inferred from mutant phenotype PubMed 7550343PubMed 7618107PubMed 7774020. Source: MGI

grooming behavior

Inferred from mutant phenotype PubMed 10778856. Source: MGI

hormone metabolic process

Inferred from mutant phenotype PubMed 10078572PubMed 10739639. Source: MGI

insulin secretion

Inferred from mutant phenotype PubMed 10078572. Source: MGI

iron ion homeostasis

Inferred from mutant phenotype PubMed 11092755. Source: MGI

lactate biosynthetic process from pyruvate

Inferred from mutant phenotype PubMed 17708681. Source: MGI

learning

Inferred from mutant phenotype PubMed 16624677. Source: MGI

learning or memory

Inferred from mutant phenotype PubMed 16403806. Source: MGI

locomotory behavior

Inferred from mutant phenotype PubMed 10778856PubMed 11062468PubMed 11152661PubMed 11567051PubMed 12223581PubMed 12926013PubMed 16403806PubMed 17715336PubMed 7774020. Source: MGI

mitochondrial transport

Inferred from mutant phenotype PubMed 15340079. Source: MGI

mitochondrion organization

Inferred from mutant phenotype PubMed 11092755. Source: MGI

negative regulation of apoptotic process

Inferred from direct assay PubMed 15242649. Source: MGI

negative regulation of extrinsic apoptotic signaling pathway

Inferred from electronic annotation. Source: Ensembl

negative regulation of neuron apoptotic process

Inferred from mutant phenotype PubMed 11152661. Source: MGI

neural plate formation

Inferred from mutant phenotype PubMed 7774020. Source: MGI

neurogenesis

Inferred from mutant phenotype PubMed 11062468. Source: MGI

neuron apoptotic process

Inferred from mutant phenotype PubMed 10082833PubMed 10932179. Source: MGI

neuron development

Inferred from mutant phenotype PubMed 10082833PubMed 16978870PubMed 7774020. Source: MGI

olfactory lobe development

Inferred from mutant phenotype PubMed 12926013. Source: MGI

paraxial mesoderm formation

Inferred from mutant phenotype PubMed 16109169. Source: MGI

peptide hormone secretion

Inferred from mutant phenotype PubMed 10078572PubMed 12223581. Source: MGI

protein import into nucleus

Inferred from mutant phenotype PubMed 11092755. Source: MGI

quinolinate biosynthetic process

Inferred from mutant phenotype PubMed 16697652. Source: MGI

regulation of mitochondrial membrane permeability

Inferred from mutant phenotype PubMed 15935052. Source: MGI

regulation of mitochondrial membrane potential

Inferred from mutant phenotype PubMed 17708681. Source: MGI

regulation of protein export from nucleus

Inferred from electronic annotation. Source: Ensembl

regulation of protein phosphatase type 2A activity

Inferred from electronic annotation. Source: Ensembl

regulation of synaptic plasticity

Inferred from mutant phenotype PubMed 10196373PubMed 17442827. Source: MGI

response to calcium ion

Inferred from mutant phenotype PubMed 15935052. Source: MGI

retrograde vesicle-mediated transport, Golgi to ER

Inferred from electronic annotation. Source: Ensembl

social behavior

Inferred from mutant phenotype PubMed 10196365. Source: MGI

spermatogenesis

Inferred from mutant phenotype PubMed 11062468. Source: MGI

striatum development

Inferred from mutant phenotype PubMed 11030759PubMed 17715336. Source: MGI

urea cycle

Inferred from mutant phenotype PubMed 17213233. Source: MGI

vesicle transport along microtubule

Inferred from direct assay PubMed 15242649. Source: MGI

visual learning

Inferred from mutant phenotype PubMed 7774020. Source: MGI

   Cellular_componentGolgi apparatus

Inferred from electronic annotation. Source: Ensembl

autophagic vacuole

Inferred from electronic annotation. Source: Ensembl

axon

Inferred from direct assay PubMed 12115678PubMed 8757264. Source: MGI

cytoplasm

Inferred from direct assay PubMed 10699173PubMed 16403806PubMed 7647777PubMed 7662892PubMed 8757264. Source: MGI

cytoplasmic membrane-bounded vesicle

Inferred from direct assay PubMed 15242649. Source: MGI

cytoplasmic vesicle membrane

Inferred from electronic annotation. Source: Ensembl

cytosol

Inferred from electronic annotation. Source: Ensembl

dendrite

Inferred from electronic annotation. Source: Ensembl

endoplasmic reticulum

Inferred from electronic annotation. Source: Ensembl

inclusion body

Inferred from direct assay PubMed 15615787. Source: MGI

late endosome

Inferred from electronic annotation. Source: Ensembl

mitochondrion

Inferred from mutant phenotype PubMed 15935052. Source: GOC

nucleus

Inferred from Biological aspect of Ancestor. Source: RefGenome

protein complex

Inferred from electronic annotation. Source: Ensembl

   Molecular_functiondiazepam binding

Inferred from mutant phenotype PubMed 10082833. Source: MGI

transcription factor binding

Inferred from physical interaction PubMed 18595722. Source: MGI

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
G3X9H5 [UniParc].

Last modified November 16, 2011. Version 1.
Checksum: 53CCDC45D53B8BA3

FASTA3,120344,788
        10         20         30         40         50         60 
MATLEKLMKA FESLKSFQQQ QQQQPPPQAP PPPPPPPPPQ PPQPPPQGQP PPPPPPLPGP 

        70         80         90        100        110        120 
AEEPLHRPKK ELSATKKDRV NHCLTICENI VAQSLRNSPE FQKLLGIAME LFLLCSDDAE 

       130        140        150        160        170        180 
SDVRMVADEC LNKVIKALMD SNLPRLQLEL YKEIKKNGAP RSLRAALWRF AELAHLVRPQ 

       190        200        210        220        230        240 
KCRPYLVNLL PCLTRTSKRP EESVQETLAA AVPKIMASFG NFANDNEIKV LLKAFIANLK 

       250        260        270        280        290        300 
SSSPTVRRTA AGSAVSICQH SRRTQYFYNW LLNVLLGLLV PMEEEHSTLL ILGVLLTLRC 

       310        320        330        340        350        360 
LVPLLQQQVK DTSLKGSFGV TRKEMEVSPS TEQLVQVYEL TLHHTQHQDH NVVTGALELL 

       370        380        390        400        410        420 
QQLFRTPPPE LLQALTTPGG LGQLTLVQEE ARGRGRSGSI VELLAGGGSS CSPVLSRKQK 

       430        440        450        460        470        480 
GKVLLGEEEA LEDDSESRSD VSSSAFAASV KSEIGGELAA SSGVSTPGSV GHDIITEQPR 

       490        500        510        520        530        540 
SQHTLQADSV DLSGCDLTSA ATDGDEEDIL SHSSSQFSAV PSDPAMDLND GTQASSPISD 

       550        560        570        580        590        600 
SSQTTTEGPD SAVTPSDSSE IVLDGADSQY LGMQIGQPQE DDEEGAAGVL SGEVSDVFRN 

       610        620        630        640        650        660 
SSLALQQAHL LERMGHSRQP SDSSIDKYVT RDEVAEASDP ESKPCRIKGD IGQPNDDDSA 

       670        680        690        700        710        720 
PLVHCVRLLS ASFLLTGEKK ALVPDRDVRV SVKALALSCI GAAVALHPES FFSRLYKVPL 

       730        740        750        760        770        780 
NTTESTEEQY VSDILNYIDH GDPQVRGATA ILCGTLVYSI LSRSRLRVGD WLGNIRTLTG 

       790        800        810        820        830        840 
NTFSLVDCIP LLQKTLKDES SVTCKLACTA VRHCVLSLCS SSYSDLGLQL LIDMLPLKNS 

       850        860        870        880        890        900 
SYWLVRTELL DTLAEIDFRL VSFLEAKAES LHRGAHHYTG FLKLQERVLN NVVIYLLGDE 

       910        920        930        940        950        960 
DPRVRHVAAT SLTRLVPKLF YKCDQGQADP VVAVARDQSS VYLKLLMHET QPPSHFSVST 

       970        980        990       1000       1010       1020 
ITRIYRGYSL LPSITDVTME NNLSRVVAAV SHELITSTTR ALTFGCCEAL CLLSAAFPVC 

      1030       1040       1050       1060       1070       1080 
TWSLGWHCGV PPLSASDESR KSCTVGMASM ILTLLSSAWF PLDLSAHQDA LILAGNLLAA 

      1090       1100       1110       1120       1130       1140 
SAPKSLRSSW TSEEEANSAA TRQEEIWPAL GDRTLVPLVE QLFSHLLKVI NICAHVLDDV 

      1150       1160       1170       1180       1190       1200 
TPGPAIKAAL PSLTNPPSLS PIRRKGKEKE PGEQASTPMS PKKVGEASAA SRQSDTSGPV 

      1210       1220       1230       1240       1250       1260 
TASKSSSLGS FYHLPSYLKL HDVLKATHAN YKVTLDLQNS TEKFGGFLRS ALDVLSQILE 

      1270       1280       1290       1300       1310       1320 
LATLQDIGKC VEEVLGYLKS CFSREPMMAT VCVQQLLKTL FGTNLASQFD GLSSNPSKSQ 

      1330       1340       1350       1360       1370       1380 
CRAQRLGSSS VRPGLYHYCF MAPYTHFTQA LADASLRNMV QAEQERDASG WFDVLQKVSA 

      1390       1400       1410       1420       1430       1440 
QLKTNLTSVT KNRADKNAIH NHIRLFEPLV IKALKQYTTT TSVQLQKQVL DLLAQLVQLR 

      1450       1460       1470       1480       1490       1500 
VNYCLLDSDQ VFIGFVLKQF EYIEVGQFRE SEAIIPNIFF FLVLLSYERY HSKQIIGIPK 

      1510       1520       1530       1540       1550       1560 
IIQLCDGIMA SGRKAVTHAI PALQPIVHDL FVLRGTNKAD AGKELETQKE VVVSMLLRLI 

      1570       1580       1590       1600       1610       1620 
QYHQVLEMFI LVLQQCHKEN EDKWKRLSRQ VADIILPMLA KQQMHIDSHE ALGVLNTLFE 

      1630       1640       1650       1660       1670       1680 
ILAPSSLRPV DMLLRSMFIT PSTMASVSTV QLWISGILAI LRVLISQSTE DIVLCRIQEL 

      1690       1700       1710       1720       1730       1740 
SFSPHLLSCP VINRLRGGGG NVTLGECSEG KQKSLPEDTF SRFLLQLVGI LLEDIVTKQL 

      1750       1760       1770       1780       1790       1800 
KVDMSEQQHT FYCQELGTLL MCLIHIFKSG MFRRITAAAT RLFTSDGCEG SFYTLESLNA 

      1810       1820       1830       1840       1850       1860 
RVRSMVPTHP ALVLLWCQIL LLINHTDHRW WAEVQQTPKR HSLSCTKSLN PQKSGEEEDS 

      1870       1880       1890       1900       1910       1920 
GSAAQLGMCN REIVRRGALI LFCDYVCQNL HDSEHLTWLI VNHIQDLISL SHEPPVQDFI 

      1930       1940       1950       1960       1970       1980 
SAIHRNSAAS GLFIQAIQSR CENLSTPTTL KKTLQCLEGI HLSQSGAVLT LYVDRLLGTP 

      1990       2000       2010       2020       2030       2040 
FRALARMVDT LACRRVEMLL AANLQSSMAQ LPEEELNRIQ EHLQNSGLAQ RHQRLYSLLD 

      2050       2060       2070       2080       2090       2100 
RFRLSTVQDS LSPLPPVTSH PLDGDGHTSL ETVSPDKDWY LQLVRSQCWT RSDSALLEGA 

      2110       2120       2130       2140       2150       2160 
ELVNRIPAED MNDFMMSSEF NLSLLAPCLS LGMSEIANGQ KSPLFEAARG VILNRVTSVV 

      2170       2180       2190       2200       2210       2220 
QQLPAVHQVF QPFLPIEPTA YWNKLNDLLG DTTSYQSLTI LARALAQYLV VLSKVPAHLH 

      2230       2240       2250       2260       2270       2280 
LPPEKEGDTV KFVVMTVEAL SWHLIHEQIP LSLDLQAGLD CCCLALQVPG LWGVLSSPEY 

      2290       2300       2310       2320       2330       2340 
VTHACSLIHC VRFILEAIAV QPGDQLLGPE SRSHTPRAVR KEEVDSDIQN LSHVTSACEM 

      2350       2360       2370       2380       2390       2400 
VADMVESLQS VLALGHKRNS TLPSFLTAVL KNIVISLARL PLVNSYTRVP PLVWKLGWSP 

      2410       2420       2430       2440       2450       2460 
KPGGDFGTVF PEIPVEFLQE KEILKEFIYR INTLGWTNRT QFEETWATLL GVLVTQPLVM 

      2470       2480       2490       2500       2510       2520 
EQEESPPEED TERTQIHVLA VQAITSLVLS AMTVPVAGNP AVSCLEQQPR NKPLKALDTR 

      2530       2540       2550       2560       2570       2580 
FGRKLSMIRG IVEQEIQEMV SQRENTATHH SHQAWDPVPS LLPATTGALI SHDKLLLQIN 

      2590       2600       2610       2620       2630       2640 
PEREPGNMSY KLGQVSIHSV WLGNNITPLR EEEWDEEEEE ESDVPAPTSP PVSPVNSRKH 

      2650       2660       2670       2680       2690       2700 
RAGVDIHSCS QFLLELYSRW ILPSSAARRT PVILISEVVR SLLVVSDLFT ERTQFEMMYL 

      2710       2720       2730       2740       2750       2760 
TLTELRRVHP SEDEILIQYL VPATCKAAAV LGMDKTVAEP VSRLLESTLR SSHLPSQIGA 

      2770       2780       2790       2800       2810       2820 
LHGILYVLEC DLLDDTAKQL IPVVSDYLLS NLKGIAHCVN IHSQQHVLVM CATAFYLMEN 

      2830       2840       2850       2860       2870       2880 
YPLDVGPEFS ASVIQMCGVM LSGSEESTPS IIYHCALRGL ERLLLSEQLS RLDTESLVKL 

      2890       2900       2910       2920       2930       2940 
SVDRVNVQSP HRAMAALGLM LTCMYTGKEK ASPGRASDPS PATPDSESVI VAMERVSVLF 

      2950       2960       2970       2980       2990       3000 
DRIRKGFPCE ARVVARILPQ FLDDFFPPQD VMNKVIGEFL SNQQPYPQFM ATVVYKVFQT 

      3010       3020       3030       3040       3050       3060 
LHSAGQSSMV RDWVMLSLSN FTQRTPVAMA MWSLSCFLVS ASTSPWVSAI LPHVISRMGK 

      3070       3080       3090       3100       3110       3120 
LEQVDVNLFC LVATDFYRHQ IEEEFDRRAF QSVFEVVAAP GSPYHRLLAC LQNVHKVTTC 

« Hide

References

« Hide 'large scale' references
[1]"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. expand/collapse author list , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL37467.1.
[2]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL37467.1.
[3]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000078945.
[4]Ensembl
Submitted (SEP-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000078945.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC133204 Genomic DNA. No translation available.
AC151669 Genomic DNA. No translation available.
CH466524 Genomic DNA. Translation: EDL37467.1.
RefSeqNP_034544.1. NM_010414.2.
UniGeneMm.209071.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000080036; ENSMUSP00000078945; ENSMUSG00000029104.
GeneID15194.
KEGGmmu:15194.
UCSCuc008xdc.2. mouse.

Organism-specific databases

CTD3064.
MGIMGI:96067. Htt.

Phylogenomic databases

GeneTreeENSGT00390000015863.
KOK04533.
OMASDQVFIG.
OrthoDBEOG7JQBMD.
TreeFamTF323608.

Family and domain databases

Gene3D1.25.10.10. 4 hits.
InterProIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000091. Huntingtin.
IPR028426. Huntingtin_fam.
IPR024613. Huntingtin_middle-repeat.
[Graphical view]
PANTHERPTHR10170. PTHR10170. 1 hit.
PTHR10170:SF5. PTHR10170:SF5. 1 hit.
PfamPF12372. DUF3652. 2 hits.
[Graphical view]
PRINTSPR00375. HUNTINGTIN.
SUPFAMSSF48371. SSF48371. 8 hits.
ProtoNetSearch...

Other

ChiTaRSHTT. mouse.
NextBio287727.
SOURCESearch...

Entry information

Entry nameG3X9H5_MOUSE
AccessionPrimary (citable) accession number: G3X9H5
Entry history
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 16, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)