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Protein
Submitted name:

SEC24 related gene family, member C (S. cerevisiae), isoform CRA_a

Gene

Sec24c

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cargo loading into COPII-coated vesicle Source: Ensembl
  • intracellular protein transport Source: InterPro
  • in utero embryonic development Source: MGI

Keywordsi

Biological processProtein transportSAAS annotation, Transport

Enzyme and pathway databases

ReactomeiR-MMU-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-MMU-2132295. MHC class II antigen presentation.
R-MMU-5694530. Cargo concentration in the ER.
R-MMU-983170. Antigen Presentation: Folding, assembly and peptide loading of class I MHC.

Names & Taxonomyi

Protein namesi
Submitted name:
SEC24 related gene family, member C (S. cerevisiae), isoform CRA_aImported
Submitted name:
Sec24-related gene family, member C (S. cerevisiae)Imported
Gene namesi
Name:Sec24cImported
ORF Names:mCG_121333Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1919746. Sec24c.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000039367.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiG3X972. 59 interactors.
STRINGi10090.ENSMUSP00000045955.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini424 – 462zf-Sec23_Sec24InterPro annotationAdd BLAST39
Domaini501 – 745Sec23_trunkInterPro annotationAdd BLAST245
Domaini750 – 833Sec23_BSInterPro annotationAdd BLAST84
Domaini846 – 945Sec23_helicalInterPro annotationAdd BLAST100
Domaini965 – 1036Gelsolin-likeInterPro annotationAdd BLAST72

Phylogenomic databases

eggNOGiKOG1985. Eukaryota.
COG5028. LUCA.
GeneTreeiENSGT00590000082962.
OMAiLYCIPNT.
OrthoDBiEOG091G0288.
TreeFamiTF300464.

Family and domain databases

Gene3Di3.40.20.10. 1 hit.
3.40.50.410. 1 hit.
InterProiView protein in InterPro
IPR029006. ADF-H/Gelsolin-like_dom.
IPR007123. Gelsolin-like_dom.
IPR006900. Sec23/24_helical_dom.
IPR006896. Sec23/24_trunk_dom.
IPR012990. Sec23_24_beta_S.
IPR002035. VWF_A.
IPR006895. Znf_Sec23_Sec24.
PfamiView protein in Pfam
PF00626. Gelsolin. 1 hit.
PF08033. Sec23_BS. 1 hit.
PF04815. Sec23_helical. 1 hit.
PF04811. Sec23_trunk. 1 hit.
PF04810. zf-Sec23_Sec24. 1 hit.
SUPFAMiSSF53300. SSF53300. 1 hit.
SSF81811. SSF81811. 1 hit.
SSF82754. SSF82754. 1 hit.
SSF82919. SSF82919. 1 hit.

Sequencei

Sequence statusi: Complete.

G3X972-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVNQSAPPV PPYGQNQPIY PGYHQSSYGG QPGPAAPATP YGAYNGPVPG
60 70 80 90 100
YQQAPPQGVP RAPPSSGAPP ASAAQVPCGQ TTYGQFGQGD IQNGPSSTAQ
110 120 130 140 150
MQRVPGSQQF GPPLAPVVSQ PAVLQPYGPP PTSTQVTAQL AGMQISGAVA
160 170 180 190 200
QAPPPSGLGY GPPTSLASAS GNFPNSGPYG SYPQSQAPPL SQAQGHPGVQ
210 220 230 240 250
PPLRSAPPLA SSFTSPASGG PQMPSMTGLL PPGQGFGSLP VNQANHVSSP
260 270 280 290 300
PAPALPPGTQ MTGPPVPPPP PMHSPQQPGY QLQQNGSFGP ARGPQPNYES
310 320 330 340 350
PYPGAPTFGS QPGPPQPLPP KRLDPDAIPS PIQVIEDDRN NRGSEPFVTG
360 370 380 390 400
VRGQVPPLVT TNFLVKDQGN ASPRYIRCTS YNIPCTSDMA KQAQVPLAAV
410 420 430 440 450
IKPLARLPPE EASPYVVDHG ESGPLRCNRC KAYMCPLMTF IEGGRRFQCS
460 470 480 490 500
FCSCVNDVPP QYFQHLDHTG KRVDAYDRPE LSLGSYEFLA TVDYCKNNKF
510 520 530 540 550
PSPPAFIFMI DVSYNAIRTG LVRLLCEELK SLLDYLPREG GAEESAIRVG
560 570 580 590 600
FVTYNKVLHF YNVKSSLAQP QMMVVSDVAD MFVPLLDGFL VNVSESRAVI
610 620 630 640 650
TSLLDQIPEM FADTRETETV FAPVIQAGME ALKAAECAGK LFLFHTSLPI
660 670 680 690 700
AEAPGKLKNR DDRKLINTDK EKTLFQPQTG TYQTLAKECV AQGCCVDLFL
710 720 730 740 750
FPNQYVDVAT LSVVPQLTGG SVYKYACFQV ENDQERFLSD LRRDVQKVVG
760 770 780 790 800
FDAVMRVRTS TGIRAVDFFG AFYMSNTTDV ELAGLDGDKT VTVEFKHDDR
810 820 830 840 850
LNEENGALLQ CALLYTSCAG QRRLRIHNLA LNCCTQLADL YRNCETDTLI
860 870 880 890 900
NYMAKFAYRA VLNSPVKTVR DTLITQCAQI LACYRKNCAS PSSAGQLILP
910 920 930 940 950
ECMKLLPVYL NCVLKSDVLQ PGAEVTTDDR AYVRQLVSSM DVAETNVFFY
960 970 980 990 1000
PRLLPLTKSP LDSTAEPPAV RASEERLSSG DIYLLENGLN LFVWVGASVQ
1010 1020 1030 1040 1050
QGVVQSLFNV SSFSQITSGL SVLPVLDNPL SKKVRGLIDS LRAQRMRYMK
1060 1070 1080 1090
LIVVKQEDKL EMLFKHFLVE DKSLSGGASY VDFLCHMHKE IRQLLS
Length:1,096
Mass (Da):118,581
Last modified:November 16, 2011 - v1
Checksum:iC614860FB9EDE158
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC121599 Genomic DNA. No translation available.
CH466613 Genomic DNA. Translation: EDL01498.1.
RefSeqiNP_766184.2. NM_172596.2.
UniGeneiMm.173119.

Genome annotation databases

EnsembliENSMUST00000048657; ENSMUSP00000045955; ENSMUSG00000039367.
GeneIDi218811.
UCSCiuc007skg.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiG3X972_MOUSE
AccessioniPrimary (citable) accession number: G3X972
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 27, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported