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G3X8W6

- G3X8W6_MOUSE

UniProt

G3X8W6 - G3X8W6_MOUSE

Protein
Submitted name:

MCG1588, isoform CRA_c

Gene

Rgs11

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 24 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. GTPase activator activity Source: RefGenome
    2. signal transducer activity Source: InterPro

    GO - Biological processi

    1. G-protein coupled receptor signaling pathway Source: MGI
    2. intracellular signal transduction Source: InterPro
    3. positive regulation of GTPase activity Source: GOC
    4. termination of G-protein coupled receptor signaling pathway Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MCG1588, isoform CRA_cImported
    Submitted name:
    Regulator of G-protein-signaling 11Imported
    Gene namesi
    Name:Rgs11Imported
    ORF Names:mCG_1588Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1354739. Rgs11.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: RefGenome
    2. dendrite terminus Source: MGI
    3. heterotrimeric G-protein complex Source: InterPro
    4. plasma membrane Source: RefGenome
    5. protein complex Source: MGI

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 RGS domain.UniRule annotation
    Contains RGS domain.SAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00700000104259.
    KOiK16449.
    OMAiMQDPDMG.
    TreeFamiTF351956.

    Family and domain databases

    Gene3Di1.10.10.10. 1 hit.
    1.10.196.10. 1 hit.
    4.10.260.10. 1 hit.
    InterProiIPR000591. DEP_dom.
    IPR015898. G-protein_gamma-like_dom.
    IPR024066. Regulat_G_prot_signal_dom1.
    IPR016137. Regulat_G_prot_signal_superfam.
    IPR000342. RGS_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00610. DEP. 1 hit.
    PF00631. G-gamma. 1 hit.
    PF00615. RGS. 1 hit.
    [Graphical view]
    PRINTSiPR01301. RGSPROTEIN.
    SMARTiSM00049. DEP. 1 hit.
    SM00224. GGL. 1 hit.
    SM00315. RGS. 1 hit.
    [Graphical view]
    SUPFAMiSSF48097. SSF48097. 1 hit.
    SSF48670. SSF48670. 1 hit.
    PROSITEiPS50186. DEP. 1 hit.
    PS50132. RGS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3X8W6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAMVTRCTPH GGCSRMQRPH LSKMERVVVS MQDPDQGVKM RSQRLLITVI    50
    PHAVAGRDLV EWLVQKFCIL EDEALHLGTL LAQHGYIYPL RESRDLTLRP 100
    DETPYRFQTP YFWTSTMWPA AELDYAIYLA KKNIQKQGAL VDYEKEHYAL 150
    LHKKINHAWD LVLMQAREQL RAAKQRRKGD RMVISCQEQT YWLVNKPPPG 200
    APNILEQGPE RGSYNPSHMQ MSSDFYKCEI ECFRKALGRN RVKSSACLEA 250
    YLKFSSQHGP HDPIMSGCLP SNPWITDDVT YWAMNAPNVA APTKLRVERW 300
    SFSFRELLDD PVGRAHFMDF LQKEFSAENL SFWEACEELR FGGQAQVPTL 350
    VDSVYQQFLA PGAARWINID SRTMERTLEG LRQPHRYVLD AAQLHIYMLM 400
    KKDSYPRFLK SDIYKGLLEE AVIPLETKRW PFPFLRKPLH SSPSPALQST 450
    PREPAATSSP EGADGE 466
    Length:466
    Mass (Da):53,643
    Last modified:November 16, 2011 - v1
    Checksum:i99675728D6EBA09C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC126438 Genomic DNA. No translation available.
    CH466606 Genomic DNA. Translation: EDL22497.1.
    RefSeqiNP_001074538.1. NM_001081069.1.
    UniGeneiMm.109840.

    Genome annotation databases

    EnsembliENSMUST00000025020; ENSMUSP00000025020; ENSMUSG00000024186.
    GeneIDi50782.
    KEGGimmu:50782.
    UCSCiuc008bdr.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC126438 Genomic DNA. No translation available.
    CH466606 Genomic DNA. Translation: EDL22497.1 .
    RefSeqi NP_001074538.1. NM_001081069.1.
    UniGenei Mm.109840.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000025020 ; ENSMUSP00000025020 ; ENSMUSG00000024186 .
    GeneIDi 50782.
    KEGGi mmu:50782.
    UCSCi uc008bdr.1. mouse.

    Organism-specific databases

    CTDi 8786.
    MGIi MGI:1354739. Rgs11.

    Phylogenomic databases

    GeneTreei ENSGT00700000104259.
    KOi K16449.
    OMAi MQDPDMG.
    TreeFami TF351956.

    Miscellaneous databases

    ChiTaRSi RGS11. mouse.
    NextBioi 307737.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 1.10.10.10. 1 hit.
    1.10.196.10. 1 hit.
    4.10.260.10. 1 hit.
    InterProi IPR000591. DEP_dom.
    IPR015898. G-protein_gamma-like_dom.
    IPR024066. Regulat_G_prot_signal_dom1.
    IPR016137. Regulat_G_prot_signal_superfam.
    IPR000342. RGS_dom.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00610. DEP. 1 hit.
    PF00631. G-gamma. 1 hit.
    PF00615. RGS. 1 hit.
    [Graphical view ]
    PRINTSi PR01301. RGSPROTEIN.
    SMARTi SM00049. DEP. 1 hit.
    SM00224. GGL. 1 hit.
    SM00315. RGS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48097. SSF48097. 1 hit.
    SSF48670. SSF48670. 1 hit.
    PROSITEi PS50186. DEP. 1 hit.
    PS50132. RGS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    4. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiG3X8W6_MOUSE
    AccessioniPrimary (citable) accession number: G3X8W6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 24 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3