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Protein
Submitted name:

Serine (Or cysteine) peptidase inhibitor, clade A, member 3N, isoform CRA_a

Gene

Serpina3n

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-114608. Platelet degranulation.
R-MMU-6798695. Neutrophil degranulation.

Names & Taxonomyi

Protein namesi
Submitted name:
Serine (Or cysteine) peptidase inhibitor, clade A, member 3N, isoform CRA_aImported
Submitted name:
Serine protease inhibitor A3NImported
Gene namesi
Name:Serpina3nImported
ORF Names:mCG_3346Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:105045. Serpina3n.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501096291121 – 418Sequence analysisAdd BLAST398

Expressioni

Gene expression databases

BgeeiENSMUSG00000021091.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 417SERPINInterPro annotationAdd BLAST362

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392. Eukaryota.
COG4826. LUCA.
GeneTreeiENSGT00760000118839.
KOiK04525.
OMAiFLMIIVP.
OrthoDBiEOG091G0ION.
TreeFamiTF343201.

Family and domain databases

InterProiView protein in InterPro
IPR023795. Serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
PANTHERiPTHR11461. PTHR11461. 1 hit.
PfamiView protein in Pfam
PF00079. Serpin. 1 hit.
SMARTiView protein in SMART
SM00093. SERPIN. 1 hit.
SUPFAMiSSF56574. SSF56574. 1 hit.
PROSITEiView protein in PROSITE
PS00284. SERPIN. 1 hit.

Sequencei

Sequence statusi: Complete.

G3X8T9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFIAALGLL MAGICPAVLC FPDGTLGMDA AVQEDHDNGT QLDSLTLASI
60 70 80 90 100
NTDFAFSLYK ELVLKNPDKN IVFSPLSISA ALAVMSLGAK GNTLEEILEG
110 120 130 140 150
LKFNLTETSE ADIHQGFGHL LQRLNQPKDQ VQISTGSALF IEKRQQILTE
160 170 180 190 200
FQEKARALYQ AEAFTADFQQ PRQAKKLIND YVRKQTQGMI KELVSDLDKR
210 220 230 240 250
TLMVLVNYIY FKAKWKVPFD PLDTFKSEFY AGKRRPVIVP MMSMEDLTTP
260 270 280 290 300
YFRDEELFCT VVELKYTGNA SAMFILPDQG KMQQVEASLQ PETLRKWKNS
310 320 330 340 350
LKPRMIDELH LPKFSISTDY SLEDVLSKLG IREVFSTQAD LSAITGTKDL
360 370 380 390 400
RVSQVVHKAV LDVAETGTEA AAATGVKFVP MSAKLYPLTV YFNRPFLIMI
410
FDTETEIAPF IAKIANPK
Length:418
Mass (Da):46,766
Last modified:November 16, 2011 - v1
Checksum:iF9B291DCDDAF76F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC117194 Genomic DNA. No translation available.
CH466549 Genomic DNA. Translation: EDL18789.1.
RefSeqiNP_033278.2. NM_009252.2.
XP_011242348.1. XM_011244046.2.
UniGeneiMm.482074.

Genome annotation databases

EnsembliENSMUST00000021506; ENSMUSP00000021506; ENSMUSG00000021091.
GeneIDi20716.
KEGGimmu:20716.
UCSCiuc007oxg.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiG3X8T9_MOUSE
AccessioniPrimary (citable) accession number: G3X8T9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: September 27, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported