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Protein

Thymidine kinase

Gene

TK1

Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:TK1Imported
OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
Taxonomic identifieri9305 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
ProteomesiUP000007648 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi9305.ENSSHAP00000021482.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000011309.
InParanoidiG3X1C7.
KOiK00857.
OMAiVTKVHAI.
OrthoDBiEOG7MSMPX.
TreeFamiTF314839.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3X1C7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSCINLPTVM PGSPSKLRGQ IQVILGPMFS GKSTELMRRV RRFQIAQYKC
60 70 80 90 100
LVIKYAKDTR YGKSFSTHDR NTMEALPACL LRDVAQDALA VTVIGIDEGQ
110 120 130 140 150
FFPDIVEFSE SMANAGKTVI VAALDGTFQR KAFGNILNLV PLAESVVKLT
160 170 180 190 200
AVCMECFREA AYTKRLGVEK EVEVIGGADK YHSVCRLCYF KKFSGQSTGQ
210 220 230
ENKENCSLNG KLEDTSSCRK LFTTQQILQC SSNN
Length:234
Mass (Da):25,908
Last modified:November 16, 2011 - v1
Checksum:i637C4862B959F942
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEFK01164766 Genomic DNA. No translation available.
AEFK01164767 Genomic DNA. No translation available.
RefSeqiXP_003768701.1. XM_003768653.2.

Genome annotation databases

EnsembliENSSHAT00000021655; ENSSHAP00000021482; ENSSHAG00000018200.
GeneIDi100934882.
KEGGishr:100934882.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEFK01164766 Genomic DNA. No translation available.
AEFK01164767 Genomic DNA. No translation available.
RefSeqiXP_003768701.1. XM_003768653.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9305.ENSSHAP00000021482.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSHAT00000021655; ENSSHAP00000021482; ENSSHAG00000018200.
GeneIDi100934882.
KEGGishr:100934882.

Organism-specific databases

CTDi7083.

Phylogenomic databases

GeneTreeiENSGT00390000011309.
InParanoidiG3X1C7.
KOiK00857.
OMAiVTKVHAI.
OrthoDBiEOG7MSMPX.
TreeFamiTF314839.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiG3X1C7_SARHA
AccessioniPrimary (citable) accession number: G3X1C7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: July 22, 2015
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.