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G3X1C7

- G3X1C7_SARHA

UniProt

G3X1C7 - G3X1C7_SARHA

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Protein
Thymidine kinase
Gene
TK1
Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC
  3. zinc ion binding Source: Ensembl

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
  2. protein homotetramerization Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:TK1Imported
OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
Taxonomic identifieri9305 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
ProteomesiUP000007648: Unplaced

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000011309.
KOiK00857.
OMAiQAICLSC.
OrthoDBiEOG7MSMPX.
TreeFamiTF314839.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3X1C7-1 [UniParc]FASTAAdd to Basket

« Hide

MSCINLPTVM PGSPSKLRGQ IQVILGPMFS GKSTELMRRV RRFQIAQYKC    50
LVIKYAKDTR YGKSFSTHDR NTMEALPACL LRDVAQDALA VTVIGIDEGQ 100
FFPDIVEFSE SMANAGKTVI VAALDGTFQR KAFGNILNLV PLAESVVKLT 150
AVCMECFREA AYTKRLGVEK EVEVIGGADK YHSVCRLCYF KKFSGQSTGQ 200
ENKENCSLNG KLEDTSSCRK LFTTQQILQC SSNN 234
Length:234
Mass (Da):25,908
Last modified:November 16, 2011 - v1
Checksum:i637C4862B959F942
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AEFK01164766 Genomic DNA. No translation available.
AEFK01164767 Genomic DNA. No translation available.
RefSeqiXP_003768701.1. XM_003768653.1.

Genome annotation databases

EnsembliENSSHAT00000021655; ENSSHAP00000021482; ENSSHAG00000018200.
GeneIDi100934882.
KEGGishr:100934882.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AEFK01164766 Genomic DNA. No translation available.
AEFK01164767 Genomic DNA. No translation available.
RefSeqi XP_003768701.1. XM_003768653.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSSHAT00000021655 ; ENSSHAP00000021482 ; ENSSHAG00000018200 .
GeneIDi 100934882.
KEGGi shr:100934882.

Organism-specific databases

CTDi 7083.

Phylogenomic databases

GeneTreei ENSGT00390000011309.
KOi K00857.
OMAi QAICLSC.
OrthoDBi EOG7MSMPX.
TreeFami TF314839.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiG3X1C7_SARHA
AccessioniPrimary (citable) accession number: G3X1C7
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 14, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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