SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G3WHI2

- G3WHI2_SARHA

UniProt

G3WHI2 - G3WHI2_SARHA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Uncharacterized protein
Gene
SETDB1
Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotations, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionineSAAS annotations

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:SETDB1Imported
    OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
    Taxonomic identifieri9305 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
    ProteomesiUP000007648: Unplaced

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. chromosome Source: UniProtKB-KW
    2. nucleus Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    ChromosomeSAAS annotations, NucleusUniRule annotationSAAS annotations

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SET domain.UniRule annotation
    Contains 1 post-SET domain.UniRule annotation
    Contains 1 pre-SET domain.
    Contains SET domain.SAAS annotations
    Contains pre-SET domain.SAAS annotations

    Phylogenomic databases

    GeneTreeiENSGT00750000117355.
    KOiK11421.

    Family and domain databases

    InterProiIPR016177. DNA-bd_dom.
    IPR025796. Hist-Lys_N-MeTrfase_SETDB1.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR003606. Pre-SET_Zn-bd_sub.
    IPR001214. SET_dom.
    IPR002999. Tudor.
    [Graphical view]
    PfamiPF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00391. MBD. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00468. PreSET. 1 hit.
    SM00317. SET. 1 hit.
    SM00333. TUDOR. 2 hits.
    [Graphical view]
    SUPFAMiSSF54171. SSF54171. 1 hit.
    PROSITEiPS50982. MBD. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS51573. SAM_MT43_SUVAR39_1. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3WHI2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTSFPGCFGL GAAAAGMEPQ EIAELQQAVV EELGISMEEL RQFIDEELEK     50
    MDCVKQRKRQ LAELESWVVQ KETEVAHVDE LFDEASRAVT NCETLVKDFY 100
    SKLGLQYRES SSEDEASKPT EVIEIPDEDD DVLSVDSGDA GSRTPKDQKL 150
    REAMAALRKS AQDVQKFMDA VNKKTSSQDL NKGALGQVPV ELSKDGDLVV 200
    SMRILGKKRT KTWHKGTLIA IQTVGAGRKF KVKFDNKGKS LLSGNHIAYD 250
    YHPPADKLYV GSRVVAKYKD GNQVWLYAGI VAETPNVKNK LRFLIFFDDG 300
    YASYVTQSEL YPICRPLKKT WEDIEDISCR DFIEEYITAY PNRPMVLLKS 350
    GQLIKTEWEG TWWKSRVEEV DGSLVKILFL DDKRCEWIYR GSTRLEPMFS 400
    MKTSTASTLE KKQGGQLRTR PNMGAVRSKG PVVQYTQDLT GTGTQFKPLE 450
    PPRTPSLPAP TLSPQVADLE SLESQLAQAR KQVAKKSTSF RLGSVGSGHS 500
    SPTSPGLNEA VPGGKSAVGQ TVRLTPGSAT PGPTFPAFHG MLERAPAEPS 550
    YRAPMEKLFY LPHACSHTCL TRVRPVSNAQ YRGKNPLLVP LLYDFRRMTA 600
    RRRVNRKMGF HVIYKTPCGL CLRTMNEIER YLFETSCDFL FLEMFCLDPY 650
    VLVDRKFQPY KPFYYILDIT HGQEDVPLSC VNEIDTTPPP QVAYSKERIP 700
    GKGVFINTGW EFLVGCDCKD GCRDKSKCAC HQLTIQATAC TPGGQINPNS 750
    GYQHKRLDEC LPTGVYECNK RCKCNINMCT NRLVQHGLQV RLQLFKTQNK 800
    GWGIRCLDDI ARGSFVCIYA GKILTDDFAD KEGLEMGDEY FANLDHIESV 850
    ENFKEGYESD APCSSDSSGV DLKDQEDGNS GTEDPEESND DSSDDNFCKD 900
    EDFSTSSVWR SYATRRQTRG QKENGTSETA SKDSRPTDSG TPHLSAPQTS 950
    MGGCKPPSSE DTPKNKVATW LSCNNVSDSS FADSDSRSSF RTSEGGDGRA 1000
    GVGRGDGEKP SVSGLGVKEE GDIKAPKKEE SDEQSKIVLS SEGSRTFGYN 1050
    PSPLKTEGIK GPPSKTNIHQ ARRLVAPAQA NPDDVLTLSS STESEGESGT 1100
    SRKPVAGQAP ATAADSDDIQ TISSGSDGED YEDKKNLSGP IKRQVAVKST 1150
    RGFALKSTHG IAIKSTNMAS ADKGESVPVR KNTRQFYDGE ESCYIIDAKL 1200
    EGNLGRYLNH SCSPNLFVQN VFVDTHDLRF PWVAFFASKR IRAGTELTWD 1250
    YNYEVGSVEG KELLCCCGAI ECRGRLL 1277
    Length:1,277
    Mass (Da):141,281
    Last modified:November 16, 2011 - v1
    Checksum:i151246E30F22C589
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AEFK01176895 Genomic DNA. No translation available.
    AEFK01176896 Genomic DNA. No translation available.
    RefSeqiXP_003770007.1. XM_003769959.1.

    Genome annotation databases

    EnsembliENSSHAT00000015012; ENSSHAP00000014887; ENSSHAG00000012701.
    GeneIDi100928904.
    KEGGishr:100928904.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AEFK01176895 Genomic DNA. No translation available.
    AEFK01176896 Genomic DNA. No translation available.
    RefSeqi XP_003770007.1. XM_003769959.1.

    3D structure databases

    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSSHAT00000015012 ; ENSSHAP00000014887 ; ENSSHAG00000012701 .
    GeneIDi 100928904.
    KEGGi shr:100928904.

    Organism-specific databases

    CTDi 9869.

    Phylogenomic databases

    GeneTreei ENSGT00750000117355.
    KOi K11421.

    Family and domain databases

    InterProi IPR016177. DNA-bd_dom.
    IPR025796. Hist-Lys_N-MeTrfase_SETDB1.
    IPR001739. Methyl_CpG_DNA-bd.
    IPR003616. Post-SET_dom.
    IPR007728. Pre-SET_dom.
    IPR003606. Pre-SET_Zn-bd_sub.
    IPR001214. SET_dom.
    IPR002999. Tudor.
    [Graphical view ]
    Pfami PF01429. MBD. 1 hit.
    PF05033. Pre-SET. 1 hit.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00391. MBD. 1 hit.
    SM00508. PostSET. 1 hit.
    SM00468. PreSET. 1 hit.
    SM00317. SET. 1 hit.
    SM00333. TUDOR. 2 hits.
    [Graphical view ]
    SUPFAMi SSF54171. SSF54171. 1 hit.
    PROSITEi PS50982. MBD. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50867. PRE_SET. 1 hit.
    PS51573. SAM_MT43_SUVAR39_1. 1 hit.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiG3WHI2_SARHA
    AccessioniPrimary (citable) accession number: G3WHI2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: April 16, 2014
    This is version 17 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

    Similar proteinsi