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G3WHI2

- G3WHI2_SARHA

UniProt

G3WHI2 - G3WHI2_SARHA

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Protein
Submitted name:

Uncharacterized protein

Gene
SETDB1
Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].UniRule annotationSAAS annotations

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone-lysine N-methyltransferase activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotations, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SETDB1Imported
OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
Taxonomic identifieri9305 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
ProteomesiUP000007648: Unplaced

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. chromosome Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotations, NucleusUniRule annotationSAAS annotations

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation
Contains 1 pre-SET domain.
Contains SET domain.SAAS annotations
Contains pre-SET domain.SAAS annotations

Phylogenomic databases

GeneTreeiENSGT00750000117355.
KOiK11421.

Family and domain databases

InterProiIPR016177. DNA-bd_dom.
IPR025796. Hist-Lys_N-MeTrfase_SETDB1.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
IPR002999. Tudor.
[Graphical view]
PfamiPF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00391. MBD. 1 hit.
SM00508. PostSET. 1 hit.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
SM00333. TUDOR. 2 hits.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS51573. SAM_MT43_SUVAR39_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3WHI2-1 [UniParc]FASTAAdd to Basket

« Hide

MTSFPGCFGL GAAAAGMEPQ EIAELQQAVV EELGISMEEL RQFIDEELEK     50
MDCVKQRKRQ LAELESWVVQ KETEVAHVDE LFDEASRAVT NCETLVKDFY 100
SKLGLQYRES SSEDEASKPT EVIEIPDEDD DVLSVDSGDA GSRTPKDQKL 150
REAMAALRKS AQDVQKFMDA VNKKTSSQDL NKGALGQVPV ELSKDGDLVV 200
SMRILGKKRT KTWHKGTLIA IQTVGAGRKF KVKFDNKGKS LLSGNHIAYD 250
YHPPADKLYV GSRVVAKYKD GNQVWLYAGI VAETPNVKNK LRFLIFFDDG 300
YASYVTQSEL YPICRPLKKT WEDIEDISCR DFIEEYITAY PNRPMVLLKS 350
GQLIKTEWEG TWWKSRVEEV DGSLVKILFL DDKRCEWIYR GSTRLEPMFS 400
MKTSTASTLE KKQGGQLRTR PNMGAVRSKG PVVQYTQDLT GTGTQFKPLE 450
PPRTPSLPAP TLSPQVADLE SLESQLAQAR KQVAKKSTSF RLGSVGSGHS 500
SPTSPGLNEA VPGGKSAVGQ TVRLTPGSAT PGPTFPAFHG MLERAPAEPS 550
YRAPMEKLFY LPHACSHTCL TRVRPVSNAQ YRGKNPLLVP LLYDFRRMTA 600
RRRVNRKMGF HVIYKTPCGL CLRTMNEIER YLFETSCDFL FLEMFCLDPY 650
VLVDRKFQPY KPFYYILDIT HGQEDVPLSC VNEIDTTPPP QVAYSKERIP 700
GKGVFINTGW EFLVGCDCKD GCRDKSKCAC HQLTIQATAC TPGGQINPNS 750
GYQHKRLDEC LPTGVYECNK RCKCNINMCT NRLVQHGLQV RLQLFKTQNK 800
GWGIRCLDDI ARGSFVCIYA GKILTDDFAD KEGLEMGDEY FANLDHIESV 850
ENFKEGYESD APCSSDSSGV DLKDQEDGNS GTEDPEESND DSSDDNFCKD 900
EDFSTSSVWR SYATRRQTRG QKENGTSETA SKDSRPTDSG TPHLSAPQTS 950
MGGCKPPSSE DTPKNKVATW LSCNNVSDSS FADSDSRSSF RTSEGGDGRA 1000
GVGRGDGEKP SVSGLGVKEE GDIKAPKKEE SDEQSKIVLS SEGSRTFGYN 1050
PSPLKTEGIK GPPSKTNIHQ ARRLVAPAQA NPDDVLTLSS STESEGESGT 1100
SRKPVAGQAP ATAADSDDIQ TISSGSDGED YEDKKNLSGP IKRQVAVKST 1150
RGFALKSTHG IAIKSTNMAS ADKGESVPVR KNTRQFYDGE ESCYIIDAKL 1200
EGNLGRYLNH SCSPNLFVQN VFVDTHDLRF PWVAFFASKR IRAGTELTWD 1250
YNYEVGSVEG KELLCCCGAI ECRGRLL 1277
Length:1,277
Mass (Da):141,281
Last modified:November 16, 2011 - v1
Checksum:i151246E30F22C589
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AEFK01176895 Genomic DNA. No translation available.
AEFK01176896 Genomic DNA. No translation available.
RefSeqiXP_003770007.1. XM_003769959.1.

Genome annotation databases

EnsembliENSSHAT00000015012; ENSSHAP00000014887; ENSSHAG00000012701.
GeneIDi100928904.
KEGGishr:100928904.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AEFK01176895 Genomic DNA. No translation available.
AEFK01176896 Genomic DNA. No translation available.
RefSeqi XP_003770007.1. XM_003769959.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSSHAT00000015012 ; ENSSHAP00000014887 ; ENSSHAG00000012701 .
GeneIDi 100928904.
KEGGi shr:100928904.

Organism-specific databases

CTDi 9869.

Phylogenomic databases

GeneTreei ENSGT00750000117355.
KOi K11421.

Family and domain databases

InterProi IPR016177. DNA-bd_dom.
IPR025796. Hist-Lys_N-MeTrfase_SETDB1.
IPR001739. Methyl_CpG_DNA-bd.
IPR003616. Post-SET_dom.
IPR007728. Pre-SET_dom.
IPR003606. Pre-SET_Zn-bd_sub.
IPR001214. SET_dom.
IPR002999. Tudor.
[Graphical view ]
Pfami PF01429. MBD. 1 hit.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00391. MBD. 1 hit.
SM00508. PostSET. 1 hit.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
SM00333. TUDOR. 2 hits.
[Graphical view ]
SUPFAMi SSF54171. SSF54171. 1 hit.
PROSITEi PS50982. MBD. 1 hit.
PS50868. POST_SET. 1 hit.
PS50867. PRE_SET. 1 hit.
PS51573. SAM_MT43_SUVAR39_1. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiG3WHI2_SARHA
AccessioniPrimary (citable) accession number: G3WHI2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 16, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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