G3WHI2 (G3WHI2_SARHA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSSHAP00000014887

Gene names

Name:

SETDB1 Ensembl ENSSHAP00000014887

Organism

Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius) [Reference proteome] Ensembl ENSSHAP00000014887

Taxonomic identifier

9305 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Metatheria › Dasyuromorphia › Dasyuridae › Sarcophilus

Protein attributes

Sequence length	1277 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS007728 S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N(6)-methyl-L-lysine. RuleBase RU004542
Subcellular location	Nucleus By similarity RuleBase RU004542.
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS007728 Contains 1 post-SET domain. Contains 1 pre-SET domain. RuleBase RU004542
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSSHAP00000014887

Ontologies

Keywords
Cellular component	Chromosome SAAS SAAS007728 Nucleus SAAS SAAS007728 RuleBase RU004542
Molecular function	Methyltransferase RuleBase RU004541 SAAS SAAS007728 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	chromosome Inferred from electronic annotation. Source: UniProtKB-KW nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G3WHI2 [UniParc]. Last modified November 16, 2011. Version 1. Checksum: 151246E30F22C589	FASTA	1,277	141,281
	10 20 30 40 50 60 MTSFPGCFGL GAAAAGMEPQ EIAELQQAVV EELGISMEEL RQFIDEELEK MDCVKQRKRQ 70 80 90 100 110 120 LAELESWVVQ KETEVAHVDE LFDEASRAVT NCETLVKDFY SKLGLQYRES SSEDEASKPT 130 140 150 160 170 180 EVIEIPDEDD DVLSVDSGDA GSRTPKDQKL REAMAALRKS AQDVQKFMDA VNKKTSSQDL 190 200 210 220 230 240 NKGALGQVPV ELSKDGDLVV SMRILGKKRT KTWHKGTLIA IQTVGAGRKF KVKFDNKGKS 250 260 270 280 290 300 LLSGNHIAYD YHPPADKLYV GSRVVAKYKD GNQVWLYAGI VAETPNVKNK LRFLIFFDDG 310 320 330 340 350 360 YASYVTQSEL YPICRPLKKT WEDIEDISCR DFIEEYITAY PNRPMVLLKS GQLIKTEWEG 370 380 390 400 410 420 TWWKSRVEEV DGSLVKILFL DDKRCEWIYR GSTRLEPMFS MKTSTASTLE KKQGGQLRTR 430 440 450 460 470 480 PNMGAVRSKG PVVQYTQDLT GTGTQFKPLE PPRTPSLPAP TLSPQVADLE SLESQLAQAR 490 500 510 520 530 540 KQVAKKSTSF RLGSVGSGHS SPTSPGLNEA VPGGKSAVGQ TVRLTPGSAT PGPTFPAFHG 550 560 570 580 590 600 MLERAPAEPS YRAPMEKLFY LPHACSHTCL TRVRPVSNAQ YRGKNPLLVP LLYDFRRMTA 610 620 630 640 650 660 RRRVNRKMGF HVIYKTPCGL CLRTMNEIER YLFETSCDFL FLEMFCLDPY VLVDRKFQPY 670 680 690 700 710 720 KPFYYILDIT HGQEDVPLSC VNEIDTTPPP QVAYSKERIP GKGVFINTGW EFLVGCDCKD 730 740 750 760 770 780 GCRDKSKCAC HQLTIQATAC TPGGQINPNS GYQHKRLDEC LPTGVYECNK RCKCNINMCT 790 800 810 820 830 840 NRLVQHGLQV RLQLFKTQNK GWGIRCLDDI ARGSFVCIYA GKILTDDFAD KEGLEMGDEY 850 860 870 880 890 900 FANLDHIESV ENFKEGYESD APCSSDSSGV DLKDQEDGNS GTEDPEESND DSSDDNFCKD 910 920 930 940 950 960 EDFSTSSVWR SYATRRQTRG QKENGTSETA SKDSRPTDSG TPHLSAPQTS MGGCKPPSSE 970 980 990 1000 1010 1020 DTPKNKVATW LSCNNVSDSS FADSDSRSSF RTSEGGDGRA GVGRGDGEKP SVSGLGVKEE 1030 1040 1050 1060 1070 1080 GDIKAPKKEE SDEQSKIVLS SEGSRTFGYN PSPLKTEGIK GPPSKTNIHQ ARRLVAPAQA 1090 1100 1110 1120 1130 1140 NPDDVLTLSS STESEGESGT SRKPVAGQAP ATAADSDDIQ TISSGSDGED YEDKKNLSGP 1150 1160 1170 1180 1190 1200 IKRQVAVKST RGFALKSTHG IAIKSTNMAS ADKGESVPVR KNTRQFYDGE ESCYIIDAKL 1210 1220 1230 1240 1250 1260 EGNLGRYLNH SCSPNLFVQN VFVDTHDLRF PWVAFFASKR IRAGTELTWD YNYEVGSVEG 1270 KELLCCCGAI ECRGRLL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil)." Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P., Tindall E.A. , Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M., Jones M.E., Schuster S.C. Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (SEP-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AEFK01176895 Genomic DNA. No translation available. AEFK01176896 Genomic DNA. No translation available.
RefSeq	XP_003770007.1. XM_003769959.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSSHAT00000015012; ENSSHAP00000014887; ENSSHAG00000012701.
GeneID	100928904.
KEGG	shr:100928904.
Organism-specific databases
CTD	9869.
Phylogenomic databases
GeneTree	ENSGT00690000101898.
KO	K11421.
Family and domain databases
InterPro	IPR016177. DNA-bd_integrase-typ. IPR025796. Hist-Lys_N-MeTrfase_SETDB1. IPR001739. Methyl_CpG_DNA-bd. IPR003616. Post-SET_dom. IPR007728. Pre-SET_dom. IPR003606. Pre-SET_Zn-bd_sub. IPR001214. SET_dom. IPR002999. Tudor. [Graphical view]
Pfam	PF01429. MBD. 1 hit. PF05033. Pre-SET. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00391. MBD. 1 hit. SM00508. PostSET. 1 hit. SM00468. PreSET. 1 hit. SM00317. SET. 1 hit. SM00333. TUDOR. 2 hits. [Graphical view]
SUPFAM	SSF54171. DNA-binding_integrase-type. 1 hit.
PROSITE	PS50982. MBD. 1 hit. PS50868. POST_SET. 1 hit. PS50867. PRE_SET. 1 hit. PS51573. SAM_MT43_SUVAR39_1. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G3WHI2_SARHA

Accession

Primary (citable) accession number: G3WHI2

Entry history

Integrated into UniProtKB/TrEMBL:	November 16, 2011
Last sequence update:	November 16, 2011
Last modified:	February 6, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)