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Protein
Submitted name:

Sphingosine-1-phosphate receptor 1

Gene

S1PR1

Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Sphingosine-1-phosphate receptor 1Imported
Gene namesi
Name:S1PR1Imported
OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
Taxonomic identifieri9305 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
Proteomesi
  • UP000007648 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei48 – 69HelicalSequence analysisAdd BLAST22
Transmembranei81 – 102HelicalSequence analysisAdd BLAST22
Transmembranei122 – 138HelicalSequence analysisAdd BLAST17
Transmembranei159 – 180HelicalSequence analysisAdd BLAST22
Transmembranei200 – 222HelicalSequence analysisAdd BLAST23
Transmembranei251 – 273HelicalSequence analysisAdd BLAST23
Transmembranei293 – 312HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9305.ENSSHAP00000014164.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 309G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST250

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IIA7. Eukaryota.
ENOG410XQD3. LUCA.
GeneTreeiENSGT00760000118804.
InParanoidiG3WFF9.
KOiK04288.
OMAiCFIACWA.
OrthoDBiEOG091G0DD4.
TreeFamiTF330052.

Family and domain databases

InterProiView protein in InterPro
IPR000987. EDG1_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR004061. S1P_rcpt.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR00642. EDG1RECEPTOR.
PR00237. GPCRRHODOPSN.
PR01523. S1PRECEPTOR.
SMARTiView protein in SMART
SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEiView protein in PROSITE
PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G3WFF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGSTSVPSVK AFPSSVSDYV NYDIIVKHYN YTGKLNPSAE GGLKVTSALF
60 70 80 90 100
ILICCFIILE NIFVLLTIWK TKKFHRPMYY FIGNLALSDL LAGVAYTANL
110 120 130 140 150
LLSGATTYKL TPAQWFLREG SMFVALSASV FSLLAIAIER YITMLKMKLH
160 170 180 190 200
NGSNSFRSFL LISACWVISL ILGGLPIMGW NCIGSLHSCS TVLPLYHKHY
210 220 230 240 250
ILFCTTVFTL LLLSIVILYC RIYSLVRTRS RRLTFRKNIS KASRSSEKSL
260 270 280 290 300
ALLKTVIIVL SAFIACWAPL FILLLLDVGC KVNTCKILYK AEYFLVLAVL
310 320 330 340 350
NSATNPIIYT LTNKEMRRAF VRIMSCCKCP SGDSGTKFKR PIIGGMEFSR
360 370 380
SKSDNSSHPQ KDDGDNPETI MSSGNVNSSS
Length:380
Mass (Da):42,267
Last modified:November 16, 2011 - v1
Checksum:i365A813B8CC03EFC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEFK01175276 Genomic DNA. No translation available.
RefSeqiXP_012404988.1. XM_012549534.1.
XP_012404989.1. XM_012549535.1.
XP_012404990.1. XM_012549536.1.

Genome annotation databases

EnsembliENSSHAT00000014281; ENSSHAP00000014164; ENSSHAG00000012106.
GeneIDi100915256.
KEGGishr:100915256.

Similar proteinsi

Entry informationi

Entry nameiG3WFF9_SARHA
AccessioniPrimary (citable) accession number: G3WFF9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: August 30, 2017
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported