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G3W9J3

- G3W9J3_SARHA

UniProt

G3W9J3 - G3W9J3_SARHA

Protein
Submitted name:

Uncharacterized protein

Gene

PCSK2

Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (16 Nov 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. serine-type endopeptidase activity Source: Ensembl

    GO - Biological processi

    1. enkephalin processing Source: Ensembl
    2. insulin processing Source: Ensembl
    3. nervous system development Source: Ensembl
    4. protein autoprocessing Source: Ensembl

    Keywords - Molecular functioni

    Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:PCSK2Imported
    OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
    Taxonomic identifieri9305 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
    ProteomesiUP000007648: Unplaced

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: Ensembl
    2. membrane Source: Ensembl

    Structurei

    3D structure databases

    ProteinModelPortaliG3W9J3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S8 family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117358.
    KOiK01360.
    OMAiDVQHLTV.
    OrthoDBiEOG7BW0JD.
    TreeFamiTF314277.

    Family and domain databases

    Gene3Di2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProiIPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view]
    PANTHERiPTHR10795. PTHR10795. 1 hit.
    PfamiPF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    [Graphical view]
    PRINTSiPR00723. SUBTILISIN.
    SUPFAMiSSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G3W9J3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQGGSVSPQW KVAVVLLCIM IFASAERPIF TNQFLVELHT GGEEEARQVA    50
    AEHGFSGIRK LPFTGGLYHF YHNGLAKTKR RRSLPHKQKL ETDPRVKMAL 100
    QQEGFDRKKR GYRDINEIDI NMNDPLFTKQ WYLINTGQAD GTPGLDLNVA 150
    EAWELGYTGK GVTIGIMDDG IDYLHPDLAA NYNAEASYDF SSNDPYPYPR 200
    YTDDWFNSHG TRCAGEVSAA ANNNICGVGV AYNSKVAGIR MLDQPFMTDI 250
    IEASSISHMP QVIDIYSASW GPTDNGKTVD GPRELTLQAM ADGVNKGRGG 300
    KGSIYVWASG DGGSYDDCNC DGYASSMWTI SINSAINDGR TALYDESCSS 350
    TLASTFSNGR KRNPEAGVAT TDLYGNCTLR HSGTSAAAPE AAGVFALALE 400
    ANRELTWRDM QHLTVLTSKR NQLHDEVHQW RRNGVGLEFN HLFGYGVLDA 450
    GAMVKMAKDW KTVPERFHCV GGSVQEPEKI PSNNKLVLTL TTDACEGKDN 500
    FVRYLEHVQA VITVNATRRG DLNINMTSPM GTKSILLSRR PRDDDSKVGF 550
    DKWPFMTTHT WGEDARGTWI LEIGFVGNAP QRGVLKEWTL MLHGTQSAPY 600
    IDQVVKDYQS KLAMSKKEEL EEELDEAVER SLKSILSKN 639
    Length:639
    Mass (Da):70,745
    Last modified:November 16, 2011 - v1
    Checksum:i75277487BA05FE4D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AEFK01029592 Genomic DNA. No translation available.
    AEFK01029593 Genomic DNA. No translation available.
    AEFK01029594 Genomic DNA. No translation available.
    AEFK01029595 Genomic DNA. No translation available.
    AEFK01029596 Genomic DNA. No translation available.
    AEFK01029597 Genomic DNA. No translation available.
    AEFK01029598 Genomic DNA. No translation available.
    AEFK01029599 Genomic DNA. No translation available.
    AEFK01029600 Genomic DNA. No translation available.
    AEFK01029601 Genomic DNA. No translation available.
    AEFK01029602 Genomic DNA. No translation available.
    AEFK01029603 Genomic DNA. No translation available.
    AEFK01029604 Genomic DNA. No translation available.
    AEFK01029605 Genomic DNA. No translation available.
    AEFK01029606 Genomic DNA. No translation available.
    AEFK01029607 Genomic DNA. No translation available.
    AEFK01029608 Genomic DNA. No translation available.
    AEFK01029609 Genomic DNA. No translation available.
    AEFK01029610 Genomic DNA. No translation available.
    AEFK01029611 Genomic DNA. No translation available.
    AEFK01029612 Genomic DNA. No translation available.
    RefSeqiXP_003758218.1. XM_003758170.1.

    Genome annotation databases

    EnsembliENSSHAT00000012196; ENSSHAP00000012098; ENSSHAG00000010370.
    GeneIDi100925659.
    KEGGishr:100925659.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AEFK01029592 Genomic DNA. No translation available.
    AEFK01029593 Genomic DNA. No translation available.
    AEFK01029594 Genomic DNA. No translation available.
    AEFK01029595 Genomic DNA. No translation available.
    AEFK01029596 Genomic DNA. No translation available.
    AEFK01029597 Genomic DNA. No translation available.
    AEFK01029598 Genomic DNA. No translation available.
    AEFK01029599 Genomic DNA. No translation available.
    AEFK01029600 Genomic DNA. No translation available.
    AEFK01029601 Genomic DNA. No translation available.
    AEFK01029602 Genomic DNA. No translation available.
    AEFK01029603 Genomic DNA. No translation available.
    AEFK01029604 Genomic DNA. No translation available.
    AEFK01029605 Genomic DNA. No translation available.
    AEFK01029606 Genomic DNA. No translation available.
    AEFK01029607 Genomic DNA. No translation available.
    AEFK01029608 Genomic DNA. No translation available.
    AEFK01029609 Genomic DNA. No translation available.
    AEFK01029610 Genomic DNA. No translation available.
    AEFK01029611 Genomic DNA. No translation available.
    AEFK01029612 Genomic DNA. No translation available.
    RefSeqi XP_003758218.1. XM_003758170.1.

    3D structure databases

    ProteinModelPortali G3W9J3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSSHAT00000012196 ; ENSSHAP00000012098 ; ENSSHAG00000010370 .
    GeneIDi 100925659.
    KEGGi shr:100925659.

    Organism-specific databases

    CTDi 5126.

    Phylogenomic databases

    GeneTreei ENSGT00750000117358.
    KOi K01360.
    OMAi DVQHLTV.
    OrthoDBi EOG7BW0JD.
    TreeFami TF314277.

    Family and domain databases

    Gene3Di 2.60.120.260. 1 hit.
    3.40.50.200. 1 hit.
    InterProi IPR008979. Galactose-bd-like.
    IPR000209. Peptidase_S8/S53_dom.
    IPR023827. Peptidase_S8_Asp-AS.
    IPR022398. Peptidase_S8_His-AS.
    IPR023828. Peptidase_S8_Ser-AS.
    IPR015500. Peptidase_S8_subtilisin-rel.
    IPR009020. Prot_inh_propept.
    IPR002884. PrprotnconvertsP.
    [Graphical view ]
    PANTHERi PTHR10795. PTHR10795. 1 hit.
    Pfami PF01483. P_proprotein. 1 hit.
    PF00082. Peptidase_S8. 1 hit.
    [Graphical view ]
    PRINTSi PR00723. SUBTILISIN.
    SUPFAMi SSF49785. SSF49785. 1 hit.
    SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    PROSITEi PS00136. SUBTILASE_ASP. 1 hit.
    PS00137. SUBTILASE_HIS. 1 hit.
    PS00138. SUBTILASE_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Ensembl
      Submitted (SEP-2011) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiG3W9J3_SARHA
    AccessioniPrimary (citable) accession number: G3W9J3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 16, 2011
    Last sequence update: November 16, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3