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Protein
Submitted name:

Uncharacterized protein

Gene

PCSK2

Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PCSK2Imported
OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
Taxonomic identifieri9305 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
ProteomesiUP000007648 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi9305.ENSSHAP00000012098.

Structurei

3D structure databases

ProteinModelPortaliG3W9J3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation
Contains peptidase S8 domain.SAAS annotation
Contains peptidase Sdomain.SAAS annotation

Phylogenomic databases

GeneTreeiENSGT00750000117358.
InParanoidiG3W9J3.
KOiK01360.
OMAiYHCEAGE.
OrthoDBiEOG7BW0JD.
TreeFamiTF314277.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G3W9J3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQGGSVSPQW KVAVVLLCIM IFASAERPIF TNQFLVELHT GGEEEARQVA
60 70 80 90 100
AEHGFSGIRK LPFTGGLYHF YHNGLAKTKR RRSLPHKQKL ETDPRVKMAL
110 120 130 140 150
QQEGFDRKKR GYRDINEIDI NMNDPLFTKQ WYLINTGQAD GTPGLDLNVA
160 170 180 190 200
EAWELGYTGK GVTIGIMDDG IDYLHPDLAA NYNAEASYDF SSNDPYPYPR
210 220 230 240 250
YTDDWFNSHG TRCAGEVSAA ANNNICGVGV AYNSKVAGIR MLDQPFMTDI
260 270 280 290 300
IEASSISHMP QVIDIYSASW GPTDNGKTVD GPRELTLQAM ADGVNKGRGG
310 320 330 340 350
KGSIYVWASG DGGSYDDCNC DGYASSMWTI SINSAINDGR TALYDESCSS
360 370 380 390 400
TLASTFSNGR KRNPEAGVAT TDLYGNCTLR HSGTSAAAPE AAGVFALALE
410 420 430 440 450
ANRELTWRDM QHLTVLTSKR NQLHDEVHQW RRNGVGLEFN HLFGYGVLDA
460 470 480 490 500
GAMVKMAKDW KTVPERFHCV GGSVQEPEKI PSNNKLVLTL TTDACEGKDN
510 520 530 540 550
FVRYLEHVQA VITVNATRRG DLNINMTSPM GTKSILLSRR PRDDDSKVGF
560 570 580 590 600
DKWPFMTTHT WGEDARGTWI LEIGFVGNAP QRGVLKEWTL MLHGTQSAPY
610 620 630
IDQVVKDYQS KLAMSKKEEL EEELDEAVER SLKSILSKN
Length:639
Mass (Da):70,745
Last modified:November 16, 2011 - v1
Checksum:i75277487BA05FE4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEFK01029592 Genomic DNA. No translation available.
AEFK01029593 Genomic DNA. No translation available.
AEFK01029594 Genomic DNA. No translation available.
AEFK01029595 Genomic DNA. No translation available.
AEFK01029596 Genomic DNA. No translation available.
AEFK01029597 Genomic DNA. No translation available.
AEFK01029598 Genomic DNA. No translation available.
AEFK01029599 Genomic DNA. No translation available.
AEFK01029600 Genomic DNA. No translation available.
AEFK01029601 Genomic DNA. No translation available.
AEFK01029602 Genomic DNA. No translation available.
AEFK01029603 Genomic DNA. No translation available.
AEFK01029604 Genomic DNA. No translation available.
AEFK01029605 Genomic DNA. No translation available.
AEFK01029606 Genomic DNA. No translation available.
AEFK01029607 Genomic DNA. No translation available.
AEFK01029608 Genomic DNA. No translation available.
AEFK01029609 Genomic DNA. No translation available.
AEFK01029610 Genomic DNA. No translation available.
AEFK01029611 Genomic DNA. No translation available.
AEFK01029612 Genomic DNA. No translation available.
RefSeqiXP_003758218.1. XM_003758170.1.

Genome annotation databases

EnsembliENSSHAT00000012196; ENSSHAP00000012098; ENSSHAG00000010370.
GeneIDi100925659.
KEGGishr:100925659.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEFK01029592 Genomic DNA. No translation available.
AEFK01029593 Genomic DNA. No translation available.
AEFK01029594 Genomic DNA. No translation available.
AEFK01029595 Genomic DNA. No translation available.
AEFK01029596 Genomic DNA. No translation available.
AEFK01029597 Genomic DNA. No translation available.
AEFK01029598 Genomic DNA. No translation available.
AEFK01029599 Genomic DNA. No translation available.
AEFK01029600 Genomic DNA. No translation available.
AEFK01029601 Genomic DNA. No translation available.
AEFK01029602 Genomic DNA. No translation available.
AEFK01029603 Genomic DNA. No translation available.
AEFK01029604 Genomic DNA. No translation available.
AEFK01029605 Genomic DNA. No translation available.
AEFK01029606 Genomic DNA. No translation available.
AEFK01029607 Genomic DNA. No translation available.
AEFK01029608 Genomic DNA. No translation available.
AEFK01029609 Genomic DNA. No translation available.
AEFK01029610 Genomic DNA. No translation available.
AEFK01029611 Genomic DNA. No translation available.
AEFK01029612 Genomic DNA. No translation available.
RefSeqiXP_003758218.1. XM_003758170.1.

3D structure databases

ProteinModelPortaliG3W9J3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9305.ENSSHAP00000012098.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSHAT00000012196; ENSSHAP00000012098; ENSSHAG00000010370.
GeneIDi100925659.
KEGGishr:100925659.

Organism-specific databases

CTDi5126.

Phylogenomic databases

GeneTreeiENSGT00750000117358.
InParanoidiG3W9J3.
KOiK01360.
OMAiYHCEAGE.
OrthoDBiEOG7BW0JD.
TreeFamiTF314277.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Prot_inh_propept.
IPR002884. PrprotnconvertsP.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF01483. P_proprotein. 1 hit.
PF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiG3W9J3_SARHA
AccessioniPrimary (citable) accession number: G3W9J3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: June 24, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.