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Protein
Submitted name:

Hexokinase 2

Gene

HK2

Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase 2Imported
Gene namesi
Name:HK2Imported
OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
Taxonomic identifieri9305 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
Proteomesi
  • UP000007648 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi9305.ENSSHAP00000011672

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 219Hexokinase_1InterPro annotationAdd BLAST198
Domaini225 – 459Hexokinase_2InterPro annotationAdd BLAST235
Domaini471 – 667Hexokinase_1InterPro annotationAdd BLAST197
Domaini673 – 907Hexokinase_2InterPro annotationAdd BLAST235

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili474 – 494Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1369 Eukaryota
COG5026 LUCA
GeneTreeiENSGT00390000017159
InParanoidiG3W8B7
KOiK00844
OMAiHAIAPVK
OrthoDBiEOG091G08MD
TreeFamiTF314238

Family and domain databases

InterProiView protein in InterPro
IPR001312 Hexokinase
IPR019807 Hexokinase_BS
IPR022673 Hexokinase_C
IPR022672 Hexokinase_N
PANTHERiPTHR19443 PTHR19443, 4 hits
PfamiView protein in Pfam
PF00349 Hexokinase_1, 2 hits
PF03727 Hexokinase_2, 2 hits
PROSITEiView protein in PROSITE
PS00378 HEXOKINASE_1, 2 hits
PS51748 HEXOKINASE_2, 2 hits

Sequencei

Sequence statusi: Complete.

G3W8B7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIASHLLAYF FTELNHDQVQ KVDQYLYHMR LSDETLEEVS KRFRKEMEKG
60 70 80 90 100
LGADTHPTAS VKMLPTFVRS TPDGTEDGDF LALDLGGTNF RVLRVRVTDN
110 120 130 140 150
GLQKVEMENQ IYAIPEAIMR GSGTQLFDHI AECLANFMDK LQIKNKKLPL
160 170 180 190 200
GFTFSFPCHQ TKLDESYLVS WTKGFKSSGV EGRDVVSLIR KAIQRRGDFD
210 220 230 240 250
IDIVAVVNDT VGTMMTCGYD DQNCEIGLIV GTGTNACYME EMRYIDTVEG
260 270 280 290 300
DEGRMCINME WGAFGDDGVL NDIRTEFDRE IDMGSLNPGK QLFEKMISGM
310 320 330 340 350
YMGELVRLIL VKMAKEELLF GGKLSPELLT TGRFETKDVS DIEGEKDGIK
360 370 380 390 400
KALEILTRLG LQPSQEDCVA THRICQIVST RSANLCAATL AAVLRRIKEN
410 420 430 440 450
KGEDRLRSTI GVDGSVYKKH PHFAKRLHKA VRRLVPDCDV RFLRSEDGSG
460 470 480 490 500
KGAAMVTAVA YRLADQHRAR QKTLEALNLS HDQLLEVKRR MKREIELGLG
510 520 530 540 550
KDTHAAASVK MLPTYVCATP DGTEKGDFLA LDLGGTNFRV LLVRVRNGMR
560 570 580 590 600
RGVEMHNKIY SIPQEVMHGT GDELFDHIVQ CIADFLEYMG MKGVSLPLGF
610 620 630 640 650
TFSFPCQQNR LDESILLKWT KGFKATGCEG EDVVGLLKEA IHRREEFDLD
660 670 680 690 700
VVAVVNDTVG TMMTCGYEDP QCEVGLIVGT GTNACYMEEM RNIELVEGDE
710 720 730 740 750
GRMCVNMEWG AFGDNGSLDD ILTEFDLAVD ELSLNPGKQR FEKMISGMYL
760 770 780 790 800
GEIVRNILIN FTKRGLLFRG RISERLKTRG IFETKFLSQI ESDCLALLQV
810 820 830 840 850
RTILRHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRQ
860 870 880 890 900
LDTLKITVGV DGTLYKLHPH FAKVMHATVK ELAPKCDVSF LESEDGSGKG
910
AALITAVACR IRDAGQR
Length:917
Mass (Da):102,358
Last modified:November 16, 2011 - v1
Checksum:i264587C5AAE77E39
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEFK01027480 Genomic DNA No translation available.
AEFK01027481 Genomic DNA No translation available.
AEFK01027482 Genomic DNA No translation available.
AEFK01027483 Genomic DNA No translation available.
AEFK01027484 Genomic DNA No translation available.
RefSeqiXP_003758010.1, XM_003757962.2

Genome annotation databases

EnsembliENSSHAT00000011768; ENSSHAP00000011672; ENSSHAG00000010027
GeneIDi100930478
KEGGishr:100930478

Similar proteinsi

Entry informationi

Entry nameiG3W8B7_SARHA
AccessioniPrimary (citable) accession number: G3W8B7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 25, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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