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Protein

p2X purinoceptor

Gene

P2RX2

Organism
Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Protein inferred from homologyi

Functioni

Receptor for ATP that acts as a ligand-gated ion channel.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelUniRule annotation, ReceptorUniRule annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
p2X purinoceptorUniRule annotation
Gene namesi
Name:P2RX2Imported
OrganismiSarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius)Imported
Taxonomic identifieri9305 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDasyuromorphiaDasyuridaeSarcophilus
Proteomesi
  • UP000007648 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei292 – 314HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9305.ENSSHAP00000011084.

Family & Domainsi

Sequence similaritiesi

Belongs to the P2X receptor family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG410IGJK. Eukaryota.
ENOG410ZQ3M. LUCA.
GeneTreeiENSGT00390000016028.
InParanoidiG3W6M9.
OMAiDVIVHGQ.
OrthoDBiEOG091G0A2U.
TreeFamiTF328633.

Family and domain databases

Gene3Di2.60.490.10. 1 hit.
InterProiView protein in InterPro
IPR003045. P2X2_purnocptor.
IPR027309. P2X_extracellular_dom_sf.
IPR001429. P2X_purnocptor.
PANTHERiPTHR10125. PTHR10125. 1 hit.
PfamiView protein in Pfam
PF00864. P2X_receptor. 1 hit.
PIRSFiPIRSF005713. P2X_purinoceptor. 1 hit.
PRINTSiPR01309. P2X2RECEPTOR.
PR01307. P2XRECEPTOR.
TIGRFAMsiTIGR00863. P2X. 1 hit.
PROSITEiView protein in PROSITE
PS01212. P2X_RECEPTOR. 1 hit.

Sequencei

Sequence statusi: Complete.

G3W6M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ALLGRYVFII QKGYQDSETG PESSVITKVK GITKSQDKVW DVEEYVKPPE
60 70 80 90 100
GGSVFSIITR AEITPFQTLG TCPESIRIRN ATCFSDDDCI AGEMDMLGNG
110 120 130 140 150
ERTGRCVPYY FGTKKTCEVS AWCPVEDGAA VSEFLGKMAP QFTILIKNSI
160 170 180 190 200
HYPKFQFSKG NIRDYDDGYL KHCTFNADTD LYCPIFKLGF IVEQAGENFT
210 220 230 240 250
ELAQKGGVIG VIINWNCDLD LSESKCNPKY SFRRLDPKHI PASSGYNYRF
260 270 280 290 300
AKYYNINGTA SRTLIKAYGI RIDVIVHGQA GKFSLIPTII NVATALTSIG
310 320 330 340 350
VGSFLCDWIL LTFMNKNKVY SHRKFDKVQP TPPPSLSLGQ RPADSSTNQS
360 370 380 390 400
QTSKPPGDQP VLHLCPWSKQ MVDTQDPSEE QGPSSPQASS QDSMPMEPKG

LSQL
Length:404
Mass (Da):44,748
Last modified:November 16, 2011 - v1
Checksum:i94B82F4BB0D75FB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEFK01070387 Genomic DNA. No translation available.
AEFK01070388 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSSHAT00000011178; ENSSHAP00000011084; ENSSHAG00000009546.

Similar proteinsi

Entry informationi

Entry nameiG3W6M9_SARHA
AccessioniPrimary (citable) accession number: G3W6M9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: November 22, 2017
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported