G3W5E3 (G3W5E3_SARHA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSSHAP00000010648

Gene names

Name:

TRAF3 Ensembl ENSSHAP00000010648

Organism

Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius) [Reference proteome] Ensembl ENSSHAP00000010648

Taxonomic identifier

9305 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Metatheria › Dasyuromorphia › Dasyuridae › Sarcophilus

Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 1 MATH domain. RuleBase RU004402 Contains 1 RING-type zinc finger. SAAS SAAS008974
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSSHAP00000010648

Ontologies

Keywords
Domain	Zinc-finger RuleBase RU000353 SAAS SAAS008974
Ligand	Metal-binding Zinc
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	Toll signaling pathway Inferred from electronic annotation. Source: InterPro innate immune response Inferred from electronic annotation. Source: InterPro negative regulation of NF-kappaB transcription factor activity Inferred from electronic annotation. Source: InterPro regulation of apoptotic process Inferred from electronic annotation. Source: InterPro regulation of cytokine production Inferred from electronic annotation. Source: InterPro regulation of defense response to virus Inferred from electronic annotation. Source: InterPro tumor necrosis factor-mediated signaling pathway Inferred from electronic annotation. Source: InterPro
Molecular_function	ubiquitin-protein ligase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	G3W5E3 [UniParc]. Last modified November 16, 2011. Version 1. Checksum: 5BE6B54C46B65C55	FASTA	567	64,596
	10 20 30 40 50 60 MDSSKKMDPP APLQTVQQKT NPDRGAGVSI YVPEQGGYKE KFVKPVEDKY KCEKCHLILC 70 80 90 100 110 120 NPKQTECGHR FCETCMHVLL SAPSPKCTAC QENIIKDKVF KDNCCKREIL ALQIYCRNES 130 140 150 160 170 180 RGCTEQLTLG HLLVHLKSDC QFEELPCVRA DCKEKILRKD LPGHVEKSCK YREATCQYCK 190 200 210 220 230 240 SQVPMITLQK HEDTDCPCVV VSCPHKCSVQ TLLRSELNAH LSECINAPST CSFKRYGCTF 250 260 270 280 290 300 QGTNQQIKTH EASSAVQHVN LLKEWSNSLE KKVSLLQNES VEKNKSIQSL HNQICSFEIE 310 320 330 340 350 360 IERQKEMLRN NESKILHLQR VIDSQAEKLK ELDKEIRPFR QNWEEADSMK SSVESLQNRV 370 380 390 400 410 420 TELESVDKSA GQAARNTGLL ETQLSRHDQM LSVHDIRLAD MDLRFQVLET ASYNGVLIWK 430 440 450 460 470 480 IRDYKRRKQE AVMGKTLSLY SQPFYTGYFG YKMCARVYLN GDGMGKGTHL SLFFVIMRGE 490 500 510 520 530 540 YDALLPWPFK QKVTLMLMDQ GSSRRHLGDA FKPDPNSSSF KKPTGEMNIA SGCPVFVAQT 550 560 VLENGTYIKD DTIFIKVIVD TSDLPDP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil)." Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P., Tindall E.A. , Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M., Jones M.E., Schuster S.C. Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Ensembl Submitted (SEP-2011) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AEFK01015216 Genomic DNA. No translation available. AEFK01015217 Genomic DNA. No translation available. AEFK01015218 Genomic DNA. No translation available. AEFK01015219 Genomic DNA. No translation available. AEFK01015220 Genomic DNA. No translation available. AEFK01015221 Genomic DNA. No translation available.
RefSeq	XP_003756576.1. XM_003756528.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSSHAT00000010742; ENSSHAP00000010648; ENSSHAG00000009189.
GeneID	100926344.
KEGG	shr:100926344.
Organism-specific databases
CTD	7187.
Phylogenomic databases
GeneTree	ENSGT00550000074359.
KO	K03174.
OMA	YGCTFQG.
Family and domain databases
Gene3D	3.30.40.10. 1 hit. 3.90.890.10. 1 hit.
InterPro	IPR002083. MATH. IPR013323. SIAH-type. IPR012227. TNF_rcpt--assoc_TRAF. IPR008974. TRAF-like. IPR027128. TRAF3. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR017907. Znf_RING_CS. IPR001293. Znf_TRAF. [Graphical view]
PANTHER	PTHR10131:SF45. PTHR10131:SF45. 1 hit.
Pfam	PF00917. MATH. 1 hit. [Graphical view]
PIRSF	PIRSF015614. TRAF. 1 hit.
SMART	SM00061. MATH. 1 hit. SM00184. RING. 1 hit. [Graphical view]
SUPFAM	SSF49599. Traf_like. 2 hits.
PROSITE	PS50144. MATH. 1 hit. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. PS50145. ZF_TRAF. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G3W5E3_SARHA

Accession

Primary (citable) accession number: G3W5E3

Entry history

Integrated into UniProtKB/TrEMBL:	November 16, 2011
Last sequence update:	November 16, 2011
Last modified:	May 1, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)