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Protein

Amine oxidase

Gene

Maoa

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

ReactomeiR-RNO-141333 Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB
R-RNO-181430 Norepinephrine Neurotransmitter Release Cycle
R-RNO-379397 Enzymatic degradation of dopamine by COMT
R-RNO-379398 Enzymatic degradation of Dopamine by monoamine oxidase
R-RNO-380612 Metabolism of serotonin

Names & Taxonomyi

Protein namesi
Recommended name:
Amine oxidaseUniRule annotation (EC:1.4.3.-UniRule annotation)
Gene namesi
Name:MaoaImported
ORF Names:rCG_42932Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi61898 Maoa

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiG3V9Z3

Expressioni

Gene expression databases

BgeeiENSRNOG00000002848

Structurei

3D structure databases

SMRiG3V9Z3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 460Amino_oxidaseInterPro annotationAdd BLAST438

Sequence similaritiesi

Belongs to the flavin monoamine oxidase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0029 Eukaryota
ENOG410XSNC LUCA
GeneTreeiENSGT00730000110903
KOiK00274
OMAiEWTRGAY
OrthoDBiEOG091G0G7P

Family and domain databases

Gene3Di3.50.50.60, 4 hits
InterProiView protein in InterPro
IPR002937 Amino_oxidase
IPR036188 FAD/NAD-bd_sf
IPR001613 Flavin_amine_oxidase
PfamiView protein in Pfam
PF01593 Amino_oxidase, 1 hit
PRINTSiPR00757 AMINEOXDASEF
SUPFAMiSSF51905 SSF51905, 2 hits

Sequencei

Sequence statusi: Complete.

G3V9Z3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDLEKPNLA GHMFDVVVIG GGISGLAAAK LLSEYKINVL VLEARDRVGG
60 70 80 90 100
RTYTVRNEHV KWVDVGGAYV GPTQNRILRL SKELGIETYK VNVNERLVQY
110 120 130 140 150
VKGKTYPFRG AFPPVWNPLA YLDYNNLWRT MDEMGKEIPV DAPWQARHAQ
160 170 180 190 200
EWDKMTMKDL IDKICWTKTA REFAYLFVNI NVTSEPHEVS ALWFLWYVRQ
210 220 230 240 250
CGGTARIFSV TNGGQERKFV GGSGQVSEQI MGLLGDKVKL SSPVTYIDQT
260 270 280 290 300
DDNIIVETLN HEHYECKYVI SAIPPILTAK IHFKPELPPE RNQLIQRLPM
310 320 330 340 350
GAVIKCMVYY KEAFWKKKDY CGCMIIEDEE APIAITLDDT KPDGSLPAIM
360 370 380 390 400
GFILARKADR LAKLHKDIRK RKICELYAKV LGSQEALYPV HYEEKNWCEE
410 420 430 440 450
QYSGGCYTAY FPPGIMTQYG RVIRQPVGRI YFAGTETATQ WSGYMEGAVE
460 470 480 490 500
AGERAAREVL NALGKVAKKD IWVEEPESKD VPAIEITHTF LERNLPSVPG
510 520
LLKITGVSTS VALLCFVLYK IKKLPC
Length:526
Mass (Da):59,521
Last modified:November 16, 2011 - v1
Checksum:iD2025A46D4CC281C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036901 Genomic DNA No translation available.
CH474009 Genomic DNA Translation: EDL97663.1
RefSeqiNP_387502.1, NM_033653.1
UniGeneiRn.224544

Genome annotation databases

EnsembliENSRNOT00000066674; ENSRNOP00000063784; ENSRNOG00000002848
GeneIDi29253
KEGGirno:29253

Similar proteinsi

Entry informationi

Entry nameiG3V9Z3_RAT
AccessioniPrimary (citable) accession number: G3V9Z3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: May 23, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health