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Protein

Amine oxidase

Gene

Maoa

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

ReactomeiR-RNO-141333. Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB.
R-RNO-181430. Norepinephrine Neurotransmitter Release Cycle.
R-RNO-379397. Enzymatic degradation of dopamine by COMT.
R-RNO-379398. Enzymatic degradation of Dopamine by monoamine oxidase.
R-RNO-380612. Metabolism of serotonin.

Names & Taxonomyi

Protein namesi
Recommended name:
Amine oxidaseUniRule annotation (EC:1.4.3.-UniRule annotation)
Gene namesi
Name:MaoaImported
ORF Names:rCG_42932Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi61898. Maoa.

Subcellular locationi

GO - Cellular componenti

Expressioni

Gene expression databases

BgeeiENSRNOG00000002848.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063784.

Structurei

3D structure databases

SMRiG3V9Z3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 460Amino_oxidaseInterPro annotationAdd BLAST438

Sequence similaritiesi

Belongs to the flavin monoamine oxidase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0029. Eukaryota.
ENOG410XSNC. LUCA.
GeneTreeiENSGT00730000110903.
KOiK00274.
OMAiDAPWEAP.
OrthoDBiEOG091G0G7P.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiView protein in InterPro
IPR002937. Amino_oxidase.
IPR023753. FAD/NAD-binding_dom.
IPR001613. Flavin_amine_oxidase.
PfamiView protein in Pfam
PF01593. Amino_oxidase. 1 hit.
PRINTSiPR00757. AMINEOXDASEF.
SUPFAMiSSF51905. SSF51905. 2 hits.

Sequencei

Sequence statusi: Complete.

G3V9Z3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDLEKPNLA GHMFDVVVIG GGISGLAAAK LLSEYKINVL VLEARDRVGG
60 70 80 90 100
RTYTVRNEHV KWVDVGGAYV GPTQNRILRL SKELGIETYK VNVNERLVQY
110 120 130 140 150
VKGKTYPFRG AFPPVWNPLA YLDYNNLWRT MDEMGKEIPV DAPWQARHAQ
160 170 180 190 200
EWDKMTMKDL IDKICWTKTA REFAYLFVNI NVTSEPHEVS ALWFLWYVRQ
210 220 230 240 250
CGGTARIFSV TNGGQERKFV GGSGQVSEQI MGLLGDKVKL SSPVTYIDQT
260 270 280 290 300
DDNIIVETLN HEHYECKYVI SAIPPILTAK IHFKPELPPE RNQLIQRLPM
310 320 330 340 350
GAVIKCMVYY KEAFWKKKDY CGCMIIEDEE APIAITLDDT KPDGSLPAIM
360 370 380 390 400
GFILARKADR LAKLHKDIRK RKICELYAKV LGSQEALYPV HYEEKNWCEE
410 420 430 440 450
QYSGGCYTAY FPPGIMTQYG RVIRQPVGRI YFAGTETATQ WSGYMEGAVE
460 470 480 490 500
AGERAAREVL NALGKVAKKD IWVEEPESKD VPAIEITHTF LERNLPSVPG
510 520
LLKITGVSTS VALLCFVLYK IKKLPC
Length:526
Mass (Da):59,521
Last modified:November 16, 2011 - v1
Checksum:iD2025A46D4CC281C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036901 Genomic DNA. No translation available.
CH474009 Genomic DNA. Translation: EDL97663.1.
RefSeqiNP_387502.1. NM_033653.1.
UniGeneiRn.224544.

Genome annotation databases

EnsembliENSRNOT00000066674; ENSRNOP00000063784; ENSRNOG00000002848.
GeneIDi29253.
KEGGirno:29253.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07036901 Genomic DNA. No translation available.
CH474009 Genomic DNA. Translation: EDL97663.1.
RefSeqiNP_387502.1. NM_033653.1.
UniGeneiRn.224544.

3D structure databases

SMRiG3V9Z3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000063784.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000066674; ENSRNOP00000063784; ENSRNOG00000002848.
GeneIDi29253.
KEGGirno:29253.

Organism-specific databases

CTDi4128.
RGDi61898. Maoa.

Phylogenomic databases

eggNOGiKOG0029. Eukaryota.
ENOG410XSNC. LUCA.
GeneTreeiENSGT00730000110903.
KOiK00274.
OMAiDAPWEAP.
OrthoDBiEOG091G0G7P.

Enzyme and pathway databases

ReactomeiR-RNO-141333. Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB.
R-RNO-181430. Norepinephrine Neurotransmitter Release Cycle.
R-RNO-379397. Enzymatic degradation of dopamine by COMT.
R-RNO-379398. Enzymatic degradation of Dopamine by monoamine oxidase.
R-RNO-380612. Metabolism of serotonin.

Gene expression databases

BgeeiENSRNOG00000002848.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiView protein in InterPro
IPR002937. Amino_oxidase.
IPR023753. FAD/NAD-binding_dom.
IPR001613. Flavin_amine_oxidase.
PfamiView protein in Pfam
PF01593. Amino_oxidase. 1 hit.
PRINTSiPR00757. AMINEOXDASEF.
SUPFAMiSSF51905. SSF51905. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiG3V9Z3_RAT
AccessioniPrimary (citable) accession number: G3V9Z3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 16, 2011
Last sequence update: November 16, 2011
Last modified: April 12, 2017
This is version 37 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.